Zobrazeno 1 - 10
of 235
pro vyhledávání: '"MASAYA IMOTO"'
Autor:
Tetsushi Kataura, Lucia Sedlackova, Congxin Sun, Gamze Kocak, Niall Wilson, Peter Banks, Faisal Hayat, Sergey Trushin, Eugenia Trushina, Oliver D. K. Maddocks, John E. Oblong, Satomi Miwa, Masaya Imoto, Shinji Saiki, Daniel Erskine, Marie E. Migaud, Sovan Sarkar, Viktor I. Korolchuk
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-13 (2024)
Abstract Impairment of autophagy leads to an accumulation of misfolded proteins and damaged organelles and has been implicated in plethora of human diseases. Loss of autophagy in actively respiring cells has also been shown to trigger metabolic colla
Externí odkaz:
https://doaj.org/article/5f963d5a91c847e89f73c916ea6f3cee
Autor:
Yuki Date, Yukiko Sasazawa, Mitsuhiro Kitagawa, Kentaro Gejima, Ayami Suzuki, Hideyuki Saya, Yasuyuki Kida, Masaya Imoto, Eisuke Itakura, Nobutaka Hattori, Shinji Saiki
Publikováno v:
eLife, Vol 13 (2024)
The autophagy-lysosome pathway plays an indispensable role in the protein quality control by degrading abnormal organelles and proteins including α-synuclein (αSyn) associated with the pathogenesis of Parkinson’s disease (PD). However, the activa
Externí odkaz:
https://doaj.org/article/8470589af0444bb5ad7fc67f5fcc1f2a
Autor:
Thanet Sophonnithiprasert, Ornjira Aruksakunwong, Etsu Tashiro, Yasumitsu Kondoh, Makoto Muroi, Hiroyuki Osada, Masaya Imoto, Ramida Watanapokasin
Publikováno v:
Heliyon, Vol 7, Iss 2, Pp e05907- (2021)
Externí odkaz:
https://doaj.org/article/70b295ae3c164c9e88a1b20f39d24a1f
Publikováno v:
Scientia Pharmaceutica, Vol 90, Iss 2, p 30 (2022)
Cinnamomum bejolghota, used in Thai traditional medicine remedies, has several biological activities including antimicrobial, antifungal, and anticancer. In colorectal cancer, epithelial-mesenchymal transition (EMT) is an initial step of cancer metas
Externí odkaz:
https://doaj.org/article/18ecb67e5ca94376a38889a0d0c53f99
Autor:
Thanet Sophonnithiprasert, Ornjira Aruksakunwong, Etsu Tashiro, Yasumitsu Kondoh, Makoto Muroi, Hiroyuki Osada, Masaya Imoto, Ramida Watanapokasin
Publikováno v:
Heliyon, Vol 6, Iss 10, Pp e05200- (2020)
Endoplasmic reticulum stress is one of the pathways involved in cell cytotoxicity. In this study, goniothalamin, one of styryllactone compounds found in plant Goniothalamus spp., was observed to trigger ER stress in HeLa cell line. In addition, we de
Externí odkaz:
https://doaj.org/article/f2df342ce57e4ce8ab1edd7a70cdc96b
Autor:
Tomoya Yamasaki, Takashi Yoshioka, Masaya Imoto, Hiroshi Aoki, Kei Fujio, Shinya Uehara, Hideo Otsuki
Publikováno v:
Case Reports in Urology, Vol 2018 (2018)
We present a case of a 45-year-old female who experienced rupture of a right calyceal diverticulum caused by ureteroscopy. Fifteen hours after the operation, she had severe right flank pain and a high fever (38.9°C). Computed tomography revealed per
Externí odkaz:
https://doaj.org/article/68345361e93a4b179c8407328de46cf6
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96776 (2014)
To explore the diversity and consistency of the signaling pathways that regulate tumor cell migration, we chose three human tumor cell lines that migrated after treatment with EGF. We then quantified the effect of fifteen inhibitors on the levels of
Externí odkaz:
https://doaj.org/article/74cfe664c4034a4a8dbd28a051610b53
Autor:
Takahiro Fujimaki, Shinji Saiki, Etsu Tashiro, Daisuke Yamada, Mitsuhiro Kitagawa, Nobutaka Hattori, Masaya Imoto
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100395 (2014)
In the course of screening for the anti-Parkinsonian drugs from a library of traditional herbal medicines, we found that the extracts of choi-joki-to and daio-kanzo-to protected cells from MPP+-induced cell death. Because choi-joki-to and daio-kanzo-
Externí odkaz:
https://doaj.org/article/8e68ff495bf54f92957609b5e5b86996
Autor:
Nobuyoshi Nagamine, Takayuki Shirakawa, Yusuke Minato, Kentaro Torii, Hiroki Kobayashi, Masaya Imoto, Yasubumi Sakakibara
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 6, p e1000397 (2009)
Predictions of interactions between target proteins and potential leads are of great benefit in the drug discovery process. We present a comprehensively applicable statistical prediction method for interactions between any proteins and chemical compo
Externí odkaz:
https://doaj.org/article/78f7a1b063ba44d6929cb4c88c1d4b95
Publikováno v:
Oncology Research; 2024, Vol. 32 Issue 1, p139-150, 12p