Zobrazeno 1 - 10
of 190
pro vyhledávání: '"MASASHI NAGATA"'
Autor:
Shunsuke Gohara, Kosuke Shinohara, Ryoji Yoshida, Ryusho Kariya, Hiroshi Tazawa, Masashi Hashimoto, Junki Inoue, Ryuta Kubo, Hikaru Nakashima, Hidetaka Arita, Sho Kawaguchi, Keisuke Yamana, Yuka Nagao, Asuka Iwamoto, Junki Sakata, Yuichiro Matsuoka, Hisashi Takeshita, Masatoshi Hirayama, Kenta Kawahara, Masashi Nagata, Akiyuki Hirosue, Yoshikazu Kuwahara, Manabu Fukumoto, Seiji Okada, Yasuo Urata, Toshiyoshi Fujiwara, Hideki Nakayama
Publikováno v:
Molecular Therapy: Oncolytics, Vol 27, Iss , Pp 141-156 (2022)
We evaluated the usefulness of an oncolytic virus (Suratadenoturev; OBP-301) against radioresistant oral squamous cell carcinoma. We confirmed the expression of human telomerase reverse transcriptase and the coxsackievirus and adenovirus receptor in
Externí odkaz:
https://doaj.org/article/d144859a11544e3599362d9d41188672
Autor:
Kenta Kawahara, Masashi Nagata, Ryoji Yoshida, Akiyuki Hirosue, Takuya Tanaka, Yuichiro Matsuoka, Hidetaka Arita, Hikaru Nakashima, Junki Sakata, Keisuke Yamana, Sho Kawaguchi, Shunsuke Gohara, Yuka Nagao, Masatoshi Hirayama, Nozomu Takahashi, Mayumi Hirayama, Hideki Nakayama
Publikováno v:
Biochemistry and Biophysics Reports, Vol 28, Iss , Pp 101114- (2021)
We aimed to determine the functional role of the miRNA, which affects drug sensitivity to 5-FU in oral squamous cell carcinoma (OSCC), using two types of 5-FU-resistant and parental OSCC cell lines. MiRNA microarray data showed that miR-30a was signi
Externí odkaz:
https://doaj.org/article/c4cd0de1a81d41e3abda7092abd3378d
Autor:
Keisuke Yamana, Junki Inoue, Ryoji Yoshida, Junki Sakata, Hikaru Nakashima, Hidetaka Arita, Sho Kawaguchi, Shunsuke Gohara, Yuka Nagao, Hisashi Takeshita, Manabu Maeshiro, Rin Liu, Yuichiro Matsuoka, Masatoshi Hirayama, Kenta Kawahara, Masashi Nagata, Akiyuki Hirosue, Ryo Toya, Ryuji Murakami, Yoshikazu Kuwahara, Manabu Fukumoto, Hideki Nakayama
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 14, Pp n/a-n/a (2021)
Abstract Despite advancements in treatments, oral squamous cell carcinoma (OSCC) has not significantly improved in prognosis or survival rate primarily due to the presence of treatment‐resistant OSCC. The intercellular communication between tumour
Externí odkaz:
https://doaj.org/article/8eaae5927b594480ad24b281659d792d
Autor:
Masatoshi Takagi, Chitose Ogawa, Yuki Aoki-Nogami, Tomoko Iehara, Eri Ishibashi, Minoru Imai, Tetsuro Kihara, Kiyoshi Nobori, Kazuhisa Hasebe, Shuki Mizutani, Toshimi Kimura, Masashi Nagata, Masato Yasuhara, Kenichi Yoshimura, Pariko Yorozu, Hajime Hosoi, Ryuji Koike
Publikováno v:
BMC Pediatrics, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background There is no established standard chemotherapy for recurrent pediatric solid tumors such as neuroblastoma and sarcoma. Since some of these tumor cells show dysfunctions in homologous recombination repair, the goal is to conduct a p
Externí odkaz:
https://doaj.org/article/5df289b40d374be6af959ad58201d71e
Autor:
Ryoji Yoshida, Shunsuke Gohara, Junki Sakata, Yuichiro Matsuoka, Akiyuki Hirosue, Kenta Kawahara, Sho Kawaguchi, Yuka Nagao, Keisuke Yamana, Masashi Nagata, Daiki Fukuma, Ryo Toya, Ryuji Murakami, Akimitsu Hiraki, Masanori Shinohara, Hideki Nakayama
Publikováno v:
Translational Oncology, Vol 13, Iss 12, Pp 100850- (2020)
Pretreatment nutritional and immunological status is useful for predicting survival outcomes for various types of malignant tumors. Our objective was to determine the impact of the pretreatment Onodera's prognostic nutritional index (OPNI) on outcome
Externí odkaz:
https://doaj.org/article/d3e350404d284662807e35921ff335e6
Autor:
Ryoji Yoshida, Masashi Nagata, Akiyuki Hirosue, Kenta Kawahara, Masafumi Nakamoto, Masatoshi Hirayama, Nozomu Takahashi, Yuichiro Matsuoka, Junki Sakata, Hikaru Nakashima, Hidetaka Arita, Akimitsu Hiraki, Masanori Shinohara, Ken Kikuchi, Hideki Nakayama
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231656 (2020)
It has been reported that 20% of early-stage oral squamous cell carcinoma (OSCC) patients treated with surgery alone (SA) may exhibit postoperative relapse within 2-3 years and have poor prognoses. We aimed to determine the safety of S-1 adjuvant che
Externí odkaz:
https://doaj.org/article/ae9b149e37c148ca8844fd4c794bccd9
Autor:
Junki Sakata, Ryoji Yoshida, Yuichiro Matsuoka, Masashi Nagata, Akiyuki Hirosue, Kenta Kawahara, Takuya Nakamura, Masafumi Nakamoto, Masatoshi Hirayama, Nozomu Takahashi, Hikaru Nakashima, Hidetaka Arita, Hidenao Ogi, Akimitsu Hiraki, Masanori Shinohara, Hideki Nakayama
Publikováno v:
Cancer Medicine, Vol 6, Iss 4, Pp 730-738 (2017)
Abstract Oral leukoplakia (OL) is a common, potentially malignant disorder of the oral cavity. SMAD4 was initially identified as a tumor suppressor and central mediator of transforming growth factor (TGF)‐β signaling. In this study, we aimed to de
Externí odkaz:
https://doaj.org/article/ae84eb7dd6ba4c0c9d435baab5344692
Autor:
Hidetaka Arita, Masashi Nagata, Ryoji Yoshida, Yuichiro Matsuoka, Akiyuki Hirosue, Kenta Kawahara, Junki Sakata, Hikaru Nakashima, Taku Kojima, Ryo Toya, Ryuji Murakami, Akimitsu Hiraki, Masanori Shinohara, Hideki Nakayama
Publikováno v:
Tumor Biology, Vol 39 (2017)
FBXW7 (F-box and WD repeat domain containing-7) is a tumor suppressor protein that regulates the degradation of various oncoproteins in several malignancies. However, limited information is available regarding FBXW7 expression in oral squamous cell c
Externí odkaz:
https://doaj.org/article/418e602d49e24abbaa3eb5b4c512b1a1
Autor:
Shizue Masuki, Kensei Nishida, Shigenari Hashimoto, Mayuko Morikawa, Satoshi Takasugi, Masashi Nagata, Shun'ichiro Taniguchi, Kazuhito Rokutan, Hiroshi Nose
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176757 (2017)
Muscle atrophy with aging is closely associated with chronic systemic inflammation and lifestyle-related diseases. In the present study, we assessed whether post-exercise milk product intake during 5-month interval walking training (IWT) enhanced the
Externí odkaz:
https://doaj.org/article/86abefd2a75f495188c864f4cee03531
Autor:
Junki Sakata, Akiyuki Hirosue, Ryoji Yoshida, Kenta Kawahara, Yuichiro Matsuoka, Tatsuro Yamamoto, Masafumi Nakamoto, Masatoshi Hirayama, Nozomu Takahashi, Takuya Nakamura, Hidetaka Arita, Hikaru Nakashima, Masashi Nagata, Akimitsu Hiraki, Masanori Shinohara, Hideki Nakayama
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 10, p 2473 (2019)
The highly malignant phenotype of oral squamous cell carcinoma (OSCC), including the presence of nodal and distant metastasis, reduces patient survival. High-mobility group A protein 2 (HMGA2) is a non-histone chromatin factor that is involved in adv
Externí odkaz:
https://doaj.org/article/83f499fddb5f4ff1a3878bf683fa6475