Výsledky vyhledávání - "MASAO SUGAMATA"

Akademický článek

Nrf2 Lowers the Risk of Lung Injury via Modulating the Airway Innate Immune Response Induced by Diesel Exhaust in Mice

Autor: Ying-Ji Li, Takako Shimizu, Yusuke Shinkai, Tomomi Ihara, Masao Sugamata, Katsuhito Kato, Maiko Kobayashi, Yukiyo Hirata, Hirofumi Inagaki, Makoto Uzuki, Toshio Akimoto, Masakazu Umezawa, Ken Takeda, Arata Azuma, Masayuki Yamamoto, Tomoyuki Kawada

Publikováno v: Biomedicines, Vol 8, Iss 10, p 443 (2020)

In the present study, we investigated the role of Nrf2 in airway immune responses induced by diesel exhaust (DE) inhalation in mice. C57BL/6J Nrf2+/+ and Nrf2−/− mice were exposed to DE or clean air for 8 h/day and 6 days/week for 4 weeks. After

Externí odkaz: https://doaj.org/article/682c858f519a442ea950725793e6f5d3

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Akademický článek

Effects of maternal exposure to ultrafine carbon black on brain perivascular macrophages and surrounding astrocytes in offspring mice.

Autor: Atsuto Onoda, Masakazu Umezawa, Ken Takeda, Tomomi Ihara, Masao Sugamata

Publikováno v: PLoS ONE, Vol 9, Iss 4, p e94336 (2014)

Perivascular macrophages (PVMs) constitute a subpopulation of resident macrophages in the central nervous system (CNS). They are located at the blood-brain barrier and can contribute to maintenance of brain functions in both health and disease condit

Externí odkaz: https://doaj.org/article/a1d566096700402cb317c71bf3e0c0e3

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Relationship Between Leukotriene Receptor Antagonists on Cancer Development in Patients With Bronchial Asthma: A Retrospective Analysis

Autor: AYAKO MAEDA-MINAMI, MAIKO HOSOKAWA, YUMI ISHIKURA, ATSUTO ONODA, YOHEI KAWANO, KENICHI NEGISHI, SHUJI SHIMADA, TOMOMI IHARA, MASAO SUGAMATA, KEN TAKEDA, YASUNARI MANO

Publikováno v: Anticancer Research. 42:3717-3724

An association between leukotriene receptor antagonists (LTRA) and cancer has been previously reported, but the relationship between LTRA use and cancer prevention remains controversial. This study aimed to clarify the cancer-preventive effect of LTR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e682caa840a39d68897708ec81cd6f
https://doi.org/10.21873/anticanres.15861

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Leukotriene Receptor Antagonist Use and Dementia Risk in Patients With Asthma: A Retrospective Cohort Study

Autor: Yohei Kawano, Ayako Maeda-Minami, Masao Sugamata, Tomomi Ihara, Atsuto Onoda, Yumi Ishikura, Yasunari Mano, Maiko Hosokawa, Ken Takeda

Publikováno v: In Vivo

Background/aim Recent experimental studies have reported that leukotriene receptor antagonists (LTRAs) might protect against dementia. However, few clinical studies have examined this in humans. This study assessed whether the use of LTRAs can preven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a24c6d4bcdb6547a10d56876cb59d7e
https://doi.org/10.21873/invivo.12625

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Overview of a New Therapy for Human Endometriosis: The Therapeutic Value of Leukotriene Receptor Antagonist for Endometriosis

Autor: Masao Sugamata, Tomomi Ihara, Ichiro Uchiide

Some drugs that regulate estrogen are currently used as therapy for endometriosis. Endometriosis is a disease characterized by the ectopic presence of endometrial tissue. However, these medical treatments have significant side effects and patients wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0003acdfac3a8a2e0acbc7bc1a5b96ec
https://doi.org/10.9734/bpi/ctmmr/v13/6646d

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A Critical Discussion: Possibility of the Strategic Treatment for Various Tumors Using the Leukotriene Receptor Antagonist Based on the Common Pathologic Findings that Mast Cells and Leukotrienes are Involved in the Development and Proliferation of Tumors

Autor: Masao Sugamata

The leukotriene receptor antagonist is indicated with a therapeutic drug of asthma and is one of the antiallergic agents. We found that mast cells and a leukotriene receptor commonly emerged for various malignant and benign tumors and proved that the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7f36abcd693b1f6a43b948fa405f0a01
https://doi.org/10.9734/bpi/ctmmr/v13/6645d

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Documenting Mast Cell Infiltration and Leukotriene Receptor Expression in Various Tumors: Possible Clinical Application of Common Pathological Findings Concerned with Tumor Development

Autor: Miho Sugamata, Masao Sugamata, Tomomi Ihara

Since the mechanisms of the developmental processes of tumors remain unclear, early detection and early treatment of the tumors is necessary to save patients with malignant tumors. Therapies currently available to patients are surgery, chemotherapy,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1953029ddd02953234367c0f3c2ad4a8
https://doi.org/10.9734/bpi/ctmmr/v13/6647d

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