Zobrazeno 1 - 10
of 158
pro vyhledávání: '"MASANORI OSHI"'
Autor:
Jeffrey C. Martin, Tatiane da Silva Fernandes, Kanita A. Chaudhry, Masanori Oshi, Scott I. Abrams, Kazuaki Takabe, Spencer R. Rosario, Anna Bianchi-Smiraglia
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Triple-negative breast cancer (TNBC) is one of the most aggressive types of cancer. Despite decades of intense investigation, treatment options remain limited, and rapid recurrence with distant metastases remains a significant challenge. Can
Externí odkaz:
https://doaj.org/article/a7c14905d0a540b290c52c0f37711b58
Autor:
Masanori Oshi, Shipra Gandhi, Rongrong Wu, Mariko Asaoka, Li Yan, Akimitsu Yamada, Shinya Yamamoto, Kazutaka Narui, Takashi Chishima, Takashi Ishikawa, Itaru Endo, Kazuaki Takabe
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-11 (2022)
Abstract Background BRCAness is a characteristic feature of homologous recombination deficiency (HRD) mimicking BRCA gene mutation in breast cancer. We hypothesized that a measure to quantify BRCAness that causes synthetic lethality in BRCA mutated t
Externí odkaz:
https://doaj.org/article/5017b9300635441caab79d7ab54c3fe7
Autor:
Masanori Oshi, Ankit Patel, Rongrong Wu, Lan Le, Yoshihisa Tokumaru, Akimitsu Yamada, Li Yan, Ryusei Matsuyama, Takashi Ishikawa, Itaru Endo, Kazuaki Takabe
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Although the value of tumor-infiltrating lymphocytes is well known, the clinical relevance of an increased immune response, specifically in breast cancer, has not been investigated across large cohorts of patients using computational algorit
Externí odkaz:
https://doaj.org/article/eaa72d2a8b7f490789450bdca11f1b29
Autor:
Shinya Yamamoto, Kei Kawashima, Yoshie Fujiwara, Shoko Adachi, Kazutaka Narui, Chiaki Hosaka, Rina Takahashi, Sho Tsuyuki, Makoto Sugimori, Miki Tanoshima, Mahato Sasamoto, Masanori Oshi, Akimitsu Yamada, Chikara Kunisaki, Itaru Endo
Publikováno v:
Clinical Case Reports, Vol 11, Iss 6, Pp n/a-n/a (2023)
Key Clinical Message A rare missense mutation was identified as a reversion mutation using cancer genomic profiling and a suspected mechanism underlying resistance to olaparib in breast cancer. Abstract A 34‐year‐old woman with breast cancer and
Externí odkaz:
https://doaj.org/article/cc65ef0df3474660a8f3df4a39f5f653
Autor:
Kei Kawashima, Shinya Yamamoto, Kazutaka Narui, Yoshie Fujiwara, Shoko Adachi, Mahato Sasamoto, Masanori Oshi, Akimitsu Yamada, Eita Kumagai, Masako Otani, Itaru Endo
Publikováno v:
Clinical Case Reports, Vol 11, Iss 3, Pp n/a-n/a (2023)
Abstract Granulomatous mastitis (GM) is a rare disease, particularly among men. Herein, we present a case of GM diagnosed in a 63‐year‐old male patient who showed reduction in the tumor size during 3 months of observation.
Externí odkaz:
https://doaj.org/article/40cf0f2620d04ad4abc11d3d8d464106
Low expression of miR-29a is associated with aggressive biology and worse survival in gastric cancer
Autor:
Yoshihisa Tokumaru, Masanori Oshi, Michelle R. Huyser, Li Yan, Masahiro Fukada, Nobuhisa Matsuhashi, Manabu Futamura, Yukihiro Akao, Kazuhiro Yoshida, Kazuaki Takabe
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Advanced gastric cancer (GC) is one of the most lethal cancer types, thus a better understanding of its biology in patients is urgently needed. MicroRNA (miR)-29a is a known tumor suppressive miR that is related to metastasis, but its clinic
Externí odkaz:
https://doaj.org/article/2e78e900ae834d0e990a3b64daadad1c
Autor:
Masanori Oshi, Yoshihisa Tokumaru, Fernando A. Angarita, Lan Lee, Li Yan, Ryusei Matsuyama, Itaru Endo, Kazuaki Takabe
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Cancer-associated adipocytes are known to cause inflammation; however, the role of adipogenesis, the formation of adipocytes, in breast cancer is unclear. We hypothesized that intra-tumoral adipogenesis reflects a different cancer biology th
Externí odkaz:
https://doaj.org/article/8e8e578ee3e7418aa94b0630ea1d77e0
Autor:
Takashi Takeshita, Yoshihisa Tokumaru, Masanori Oshi, Rongrong Wu, Ankit Patel, Wanqing Tian, Yutaka Hatanaka, Kanako C. Hatanaka, Li Yan, Kazuaki Takabe
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
PurposeEstrogen signals play an important role in the phenotype of estrogen receptor-positive breast cancer. However, comprehensive analyses of the effect of responsiveness to estrogen signals on the tumor microenvironment and survival in large cohor
Externí odkaz:
https://doaj.org/article/8b934e1c74774d65a32e5dc54525bad6
Autor:
Masanori Oshi, Yoshihisa Tokumaru, Mariko Asaoka, Li Yan, Vikas Satyananda, Ryusei Matsuyama, Nobuhisa Matsuhashi, Manabu Futamura, Takashi Ishikawa, Kazuhiro Yoshida, Itaru Endo, Kazuaki Takabe
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Tumor associated macrophages (TAMs) play a critical role in biology of various cancers, including breast cancer. In the current study, we defined “M1” macrophage and “M1”/“M2” ratio by transcriptomic signatures using xCell. We in
Externí odkaz:
https://doaj.org/article/318de2ecfd984b2d809073b5c0d913ba
Autor:
Hideo Takahashi, Mariko Asaoka, Li Yan, Omar M. Rashid, Masanori Oshi, Takashi Ishikawa, Masayuki Nagahashi, Kazuaki Takabe
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract While cancer cells gain aggressiveness by mutations, abundant mutations release neoantigens, attracting anti-cancer immune cells. We hypothesized that in breast cancer (BC), where mutation is less common, tumors with high mutation rates demo
Externí odkaz:
https://doaj.org/article/7da8c6f6d26c4ed3a1ec4b0f1f4f5d48