Zobrazeno 1 - 10
of 23
pro vyhledávání: '"MARYAM NAKHJIRI"'
Autor:
ABBAS SHAFIEE, ESKANDAR ALIPOUR, MARYAM OMRANI, MOHSEN VOSOOGHI, FARIDEH SIAVOSHI, MARYAM NAKHJIRI, SAEED EMAMI, SEYED ESMAEIL SADAT-EBRAHIMI, AZADEH YAHYA-MEYMANDI, MOHAMMAD HASSAN MOSHAFI, ALIREZA FOROUMADI
Publikováno v:
Journal of the Serbian Chemical Society, Vol 76, Iss 2, Pp 201-210 (2011)
In order to find new and potent drug candidates for the treatment of Helicobacter pylori infections‚ in this study attention was focused on the synthesis and anti-H. pylori activity of a series of 5-(5-nitrofuran-2-yl)-1,3,4-thiadiazoles containing
Externí odkaz:
https://doaj.org/article/a859d3673bda4b89b417596b5e80459e
Autor:
Pratikkumar, Patel, John, Fetse, Chien-Yu, Lin, Yuhan, Guo, Md Reaid, Hasan, Maryam, Nakhjiri, Zhen, Zhao, Akshay, Jain, Kun, Cheng
Publikováno v:
Acta Biomaterialia. 154:374-384
The use of siRNA therapeutics to treat cancer is a very promising approach. However, specific delivery of siRNAs to tumors remains a major challenge. The recent success of siRNA delivery to the liver has incentivized the development of biomaterials f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adb198d209611f95d9945fa61576c2a
https://doi.org/10.1016/j.actbio.2022.09.065
https://doi.org/10.1016/j.actbio.2022.09.065
Autor:
John Fetse, Zhen Zhao, Hao Liu, Umar-Farouk Mamani, Bahaa Mustafa, Pratik Adhikary, Mohammed Ibrahim, Yanli Liu, Pratikkumar Patel, Maryam Nakhjiri, Mohammed Alahmari, Guangfu Li, Kun Cheng
Publikováno v:
Journal of Medicinal Chemistry. 65:12002-12013
Blockade of the interaction between programmed cell death ligand-1 (PD-L1) and its receptor PD-1 has shown great success in cancer immunotherapy. Peptides possess unique characteristics that give them significant advantages as immune checkpoint inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485a6843a3d1b70faa7f45d6e6f94653
https://doi.org/10.1021/acs.jmedchem.2c00539
https://doi.org/10.1021/acs.jmedchem.2c00539
Autor:
Brian T. Chamberlain, Boris A. Kashemirov, Amirsoheil Negahbani, Pouya Haratipour, Jorge Osuna, Michelle Zhao, Corinne Minard, Maryam Nakhjiri, Charles E. McKenna, Thomas G. Upton
Publikováno v:
The Journal of Organic Chemistry. 85:14592-14609
Nucleoside 5'-triphosphate (dNTP) analogues in which the β,γ-oxygen is mimicked by a CXY group (β,γ-CXY-dNTPs) have provided information about DNA polymerase catalysis and fidelity. Definition of CXY stereochemistry is important to elucidate prec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6779f9afe0907d7b74f790da69d9357b
https://doi.org/10.1021/acs.joc.0c01204
https://doi.org/10.1021/acs.joc.0c01204
Autor:
Pouya, Haratipour, Corinne, Minard, Maryam, Nakhjiri, Amirsoheil, Negahbani, Brian T, Chamberlain, Jorge, Osuna, Thomas G, Upton, Michelle, Zhao, Boris A, Kashemirov, Charles E, McKenna
Publikováno v:
The Journal of organic chemistry. 85(22)
Nucleoside 5'-triphosphate (dNTP) analogues in which the β,γ-oxygen is mimicked by a CXY group (β,γ-CXY-dNTPs) have provided information about DNA polymerase catalysis and fidelity. Definition of CXY stereochemistry is important to elucidate prec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dbf335c24a8d05ef70b5f8ca12a41a23
https://pubmed.ncbi.nlm.nih.gov/33125847
https://pubmed.ncbi.nlm.nih.gov/33125847
Autor:
Boris A. Kashemirov, Myron F. Goodman, Maryam Nakhjiri, Amirsoheil Negahbani, Joann B. Sweasy, Ivan S. Krylov, Charles E. McKenna, Khadijeh S. Alnajjar
Publikováno v:
Biochemistry. 56:5449-5456
The hydrophobic hinge region of DNA polymerase β (pol β) is located between the fingers and palm subdomains. The hydrophobicity of the hinge region is important for maintaining the geometry of the binding pocket and for selectivity of the enzyme. V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f55a21c346270d6f8a356cf44ad9caa
https://doi.org/10.1021/acs.biochem.7b00713
https://doi.org/10.1021/acs.biochem.7b00713
Autor:
Maryam Nakhjiri, Charles E. McKenna, Amirsoheil Negahbani, Boris A. Kashemirov, Beatriz Garcia-Barboza, Joann B. Sweasy, Khadijeh S. Alnajjar, Myron F. Goodman
Publikováno v:
Biochemistry. 56:2096-2105
K289M is a variant of DNA polymerase β (pol β) that has previously been identified in colorectal cancer. The expression of this variant leads to a 16-fold increase in mutation frequency at a specific site in vivo and a reduction in fidelity in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfdadc196c441334cec28b0e925d487
https://doi.org/10.1021/acs.biochem.6b01230
https://doi.org/10.1021/acs.biochem.6b01230
Autor:
Sussan Kabudanian Ardestani, Maliheh Safavi, Mahboobeh Pordeli, Alireza Foroumadi, Maryam Nakhjiri
Publikováno v:
Breast Cancer. 24:299-311
Cancer results from a series of molecular changes that alter the normal function of cells. Breast cancer is the second leading cause of cancer death in women. To develop novel anticancer agents, new series of chromen derivatives were synthesized and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55fba77518d00039d3230e2ee3dbbc35
https://doi.org/10.1007/s12282-016-0704-5
https://doi.org/10.1007/s12282-016-0704-5
Autor:
Boris A. Kashemirov, Pouya Haratipour, Maryam Nakhjiri, Corinne Minard, Charles E. McKenna, Amirsoheil Negahbani
Publikováno v:
Phosphorus Sulfur Silicon Relat Elem
Individual diastereomers of CXY bisphosphonate analogues of dNTPs or NTPs are useful chemical stereoprobes to investigate interactions within the chiral active site environment of enzymes such as polymerases and kinases. We previously reported synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6552ec549dba30e7a2ab3f8d4e19c1f
https://doi.org/10.1080/10426507.2018.1540482
https://doi.org/10.1080/10426507.2018.1540482
Autor:
Maryam Nakhjiri, Sussan K. Ardestani, Abbas Shafiee, Eskandar Alipour, Maliheh Safavi, Alireza Foroumadi, Mona Jafari-Zavareh, Saeed Emami, Amir Farzin Atash, Mehdi Khoshneviszadeh
Publikováno v:
European Journal of Medicinal Chemistry. 50:113-123
In order to develop novel anti-cancer agents, a series of asymmetrical 2,6-bis (benzylidene)cyclohexanone derivatives containing nitrobenzylidene moiety were synthesized and their cytotoxic activity were determined in vitro against MDA-MB 231, MCF-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c122a9a27e5eab5ea67a7ff41618f73c
https://doi.org/10.1016/j.ejmech.2012.01.045
https://doi.org/10.1016/j.ejmech.2012.01.045