Zobrazeno 1 - 10
of 100
pro vyhledávání: '"MARY CATHERINE GLICK"'
Publikováno v:
Current Organic Chemistry. 8:385-394
Publikováno v:
Molecular Therapy. 7:73-80
Poly-L-lysine with 40% of the epsilon -amino groups substituted with lactosyl residues facilitated the internalization of lactosylated poly-L-lysine/cDNA complexes into cystic fibrosis (CF) and non-CF airway epithelial cells. It was previously shown
Activity of fucosyltransferases and altered glycosylation in cystic fibrosis airway epithelial cells
Publikováno v:
Biochimie. 83:743-747
Cystic fibrosis (CF) glycoconjugates have a glycosylation phenotype of increased fucosylation and/or decreased sialylation when compared with non-CF. A major increase in fucosyl residues linked alpha 1,3 to antennary GlcNAc was observed when surface
Publikováno v:
Journal of Neuroscience Research. 66:497-505
As oligodendrocytes mature they progress through a series of distinct differentiation steps characterized by the expression of specific markers. One such marker, polysialic acid found on the neural cell adhesion molecule (NCAM), is detected by antibo
Publikováno v:
Glycoconjugate Journal. 18:649-659
Altered terminal glycosylation, with increased fucosylation and decreased sialylation is a hallmark of the cystic fibrosis (CF) glycosylation phenotype. Oligosaccharides purified from the surface membrane glycoconjugates of CF airway epithelial cells
Publikováno v:
Glycoconjugate Journal. 18:731-740
Cystic fibrosis is a disease for which a number of Phase I clinical trials of gene therapy have been initiated. Several factors account for the high level of interest in a gene therapy approach to this disease. CF is the most common lethal inherited
Autor:
Vaishali A. Kothari, Paul J. Park, Mary Catherine Glick, Thomas F. Scanlin, Andrew E. Mulberg, Andrew D. Rhim
Publikováno v:
Glycoconjugate Journal. 17:385-391
Cystic fibrosis (CF) has a characteristic glycosylation phenotype usually expressed as a decreased ratio of sialic acid to fucose. The glycosylation phenotype was found in CF/T1 airway epithelial cells (ΔF508/ΔF508). When these cells were transfect
Publikováno v:
Glycobiology. 18:206-208
Autor:
Andrew E. Mulberg, Robin Eisman, Mary Catherine Glick, Thomas F. Scanlin, Xiaofang Wei, Charles L. Bevins, Jin Xu, Alan D. Harsch
Publikováno v:
Journal of Cellular Physiology. 168:373-384
The protein product of the cystic fibrosis (CF) gene, termed the cystic fibrosis transmembrane conductance regulator (CFTR), is known to function as an apical chloride channel at the surface of airway epithelial cells. It has been proposed that CFTR
Autor:
L.I. Stoykova, Mary Catherine Glick
Publikováno v:
Biochemical and Biophysical Research Communications. 217:777-783
alpha-2,8-Sialyltransferase has been purified from human neuroblastoma CHP-134 cells greater than 2900-fold. The key step in the purification was a substrate affinity column utilizing immobilized colominic acid. Several kinetic parameters of the enzy