Zobrazeno 1 - 10
of 342
pro vyhledávání: '"MARLON F. LEVY"'
Autor:
Masaya Yokoyama, Daisuke Imai, Samuel Wolfe, Ligee George, Yuzuru Sambommatsu, Aamir A. Khan, Seung Duk Lee, Muhammad I. Saeed, Amit Sharma, Vinay Kumaran, Adrian H. Cotterell, Marlon F. Levy, David A. Bruno
Publikováno v:
Livers, Vol 4, Iss 3, Pp 420-434 (2024)
Liver transplantation is the most effective treatment for end-stage liver disease. Despite improvements in surgical techniques, transplant rejection remains a significant concern. The liver is considered an immune-privileged organ due to its unique m
Externí odkaz:
https://doaj.org/article/c0b0848ceec04b838a9abaae328707d5
Autor:
Dima Malkawi, Kush Savsani, Anjelica Alfonso, Seung Duk Lee, Nicholas James, Devanand Sarkar, Daisuke Imai, Aamir Khan, Amit Sharma, Vinay Kumaran, David Bruno, Adrian Cotterell, Marlon F. Levy
Publikováno v:
Livers, Vol 3, Iss 4, Pp 709-726 (2023)
Despite improvements in short-term and long-term outcomes of liver transplant patients, the discrepancy between the number of available livers and transplant candidates continues to increase. The use of expanded criteria donors is one strategy that c
Externí odkaz:
https://doaj.org/article/8832e8c9f6de480fb04bc502581f7c9a
Autor:
Yoshitaro Shindo, Jagan Kalivarathan, Prathab Balaji Saravanan, Marlon F. Levy, Mazhar A. Kanak
Publikováno v:
Cell Transplantation, Vol 31 (2022)
Islet culture before clinical transplantation has been adopted by various centers, but its effect on the survival and function of islets relative to the culture conditions and media needs further assessment. Human islets were cultured or preserved un
Externí odkaz:
https://doaj.org/article/544185ce136144e287a426a29aceed2a
Autor:
Gumpei Yoshimatsu MD, PhD, Mazhar A. Kanak PhD, Srividya Vasu PhD, Kenjiro Kumano MD, PhD, Michael Lawrence PhD, Nicholas Onaca MD, Morihito Takita MD, PhD, Marlon F. Levy MD, Bashoo Naziruddin PhD
Publikováno v:
Cell Transplantation, Vol 29 (2020)
Total pancreatectomy with islet autotransplantation (TPIAT) is a promising treatment for refractory chronic pancreatitis (CP). Pathological features of CP include progressive fibrosis in pancreas parenchyma, atrophy, and/or ductal occlusion. Complete
Externí odkaz:
https://doaj.org/article/0480dbee746b43019313ccc3390215a4
Autor:
Ling-Jia Wang, Tatsuya Kin, Doug O'gorman, A. M. James Shapiro, Bashoo Naziruddin, Morihito Takita, Marlon F. Levy, Andrew M. Posselt, Gregory L. Szot, Omid Savari, Barbara Barbaro, James McGarrigle, Chun Chieh Yeh, Jose Oberholzer, Ji Lei, Tao Chen, Moh Lian, James F. Markmann, Alejandro Alvarez, Elina Linetsky, Camillo Ricordi, A. N. Balamurugan, Gopalakrishnan Loganathan, Joshua J. Wilhelm, Bernhard J. Hering, Rita Bottino, Massimo Trucco, Chengyang Liu, Zaw Min, Yanjing Li, Ali Naji, Luis A. Fernandez, Martynas Ziemelis, Juan S. Danobeitia, J. Michael Millis, Piotr Witkowski
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Selection of an optimal donor pancreas is the first key task for successful islet isolation. We conducted a retrospective multicenter study in 11 centers in North America to develop an islet donor scoring system using donor variables. The data set co
Externí odkaz:
https://doaj.org/article/9f115dc17ddc4fb39eca54c8386654f0
Autor:
Takeshi Itoh, Shuichi Iwahashi, Mazhar A. Kanak, Masayuki Shimoda, Morihito Takita, Daisuke Chujo, Yoshiko Tamura, Ana M. Rahman, Wen Y. Chung, Nicholas Onaca, P. Toby H. Coates, Ashley R. Dennison, Bashoo Naziruddin, Marlon F. Levy M.D., Shinichi Matsumoto
Publikováno v:
Cell Transplantation, Vol 23 (2014)
A major problem after clinical autologous islet transplantation (AIT) is the difficulty in achieving insulin independence. To follow up on our demonstration in a murine model that high-mobility group box 1 (HMGB1) was released from islets and involve
Externí odkaz:
https://doaj.org/article/44db6f88ffa648639640cce151037d33
Autor:
Mazhar A. Kanak, Morihito Takita, Faisal Kunnathodi, Michael C. Lawrence, Marlon F. Levy, Bashoo Naziruddin
Publikováno v:
International Journal of Endocrinology, Vol 2014 (2014)
Islet cell transplantation is a promising beta cell replacement therapy for patients with brittle type 1 diabetes as well as refractory chronic pancreatitis. Despite the vast advancements made in this field, challenges still remain in achieving high
Externí odkaz:
https://doaj.org/article/2cec2864af694adca698e3a98bb5fd12
Autor:
Daisuke Chujo, Emile Foucat, Morihito Takita, Takeshi Itoh, Koji Sugimoto, Masayuki Shimoda, Kunimasa Yagi, Masakazu Yamagishi, Yoshiko Tamura, Liping Yu, Bashoo Naziruddin, Marlon F. Levy, Hideki Ueno M.D., Ph.D., Shinichi Matsumoto
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Islet transplantation is one of the most promising therapies for type 1 diabetes (T1D). A major issue in islet transplantation is the loss of graft function at late phase. Several studies suggested the involvement of islet-specific T-cells in such is
Externí odkaz:
https://doaj.org/article/44049c0d2d7644c9b9abd14dceb92ad3
Autor:
Takeshi Itoh, Morihito Takita, Jeffrey A. Sorelle, Masayuki Shimoda, Koji Sugimoto, Daisuke Chujo, Huanying Qin, Bashoo Naziruddin, Marlon F. Levy M.D., F.A.C.S., Shinichi Matsumoto
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Establishing reliable islet potency assay is a critical and unmet issue for clinical islet transplantation. Recently, we reported that islets contained high levels of high mobility group box 1 (HMGB1) and damaged islets released HMGB1 in a mouse mode
Externí odkaz:
https://doaj.org/article/83a2287451b74de59161c2e6ecd9c95a
Autor:
Takeshi Itoh, Koji Sugimoto, Morihito Takita, Masayuki Shimoda, Daisuke Chujo, Jeff A. Sorelle, Bashoo Naziruddin Ph.D., Marlon F. Levy, Shinichi Matsumoto
Publikováno v:
Cell Transplantation, Vol 21 (2012)
One of the major issues in clinical islet transplantation is the poor efficacy of islet isolation. During pancreas preservation and islet isolation, islets suffer from hypoxia as islets are highly sensitive to hypoxic conditions. Cold preservation ha
Externí odkaz:
https://doaj.org/article/e0a31c2d0f924fea856087b8f604d260