Zobrazeno 1 - 10
of 101
pro vyhledávání: '"MARLENE ABSHER"'
Publikováno v:
In Free Radical Biology and Medicine 1999 27 Supplement 1:S60-S60
Autor:
Douglas G. Tilley, Donald H. Maurice, P. Marlene Absher, Heather A. Dunkerley, Daniel R. Raymond, Robert B. Vernon, Stuart J. Netherton, Daniel Palmer, Sandra L. Jimmo, E. Helene Sage, James C. Russell
Publikováno v:
Diabetes. 51:1194-1200
Cardiovascular diseases represent a significant cause of morbidity and mortality in diabetes. Of the many animal models used in the study of non-insulin-dependent (type 2) diabetes, the JCR:LA-cp rat is unique in that it develops insulin resistance i
Autor:
Marnie DeReske, P. Marlene Absher, Mary Richardson, Alan R. Giles, Yotis A. Senis, Mark W.C. Hatton, John A. Samis, Donald H. Maurice, José C.O Ribau
Publikováno v:
Atherosclerosis. 149:331-342
Endothelial cell injury has been implicated in the increased incidence of vascular disease associated with diabetes mellitus. In diabetic humans, elevated plasma von Willebrand Factor (vWF) has been interpreted as an indication of endothelial damage.
Autor:
Ping Liang, P. Marlene Absher, Burton E. Sobel, Muyao Li, Naomi K. Fukagawa, James C. Russell
Publikováno v:
Free Radical Biology and Medicine. 27:1437-1443
Deletions of mitochondrial DNA (mtDNA) are associated with aging and several chronic diseases. We have reported heterogeneous mutations between base pair 8468 and 13446 in mtDNA, the region known as the "common" deletion, in muscle of older humans wi
Publikováno v:
Atherosclerosis. 143:245-251
Proliferation in vivo of vascular smooth muscle cells occurs early in the course of atherosclerosis. Cultured smooth muscle cells (SMCs) explanted from aortas of JCR:LA-cp corpulent rats known to exhibit metabolic derangements and insulin resistance
Autor:
Patricia Q. Baumann, P. Marlene Absher, Bruce J. Leavitt, David J. Schneider, Burton E. Sobel, Jeffrey C. Reese, Michael A. Ricci, Douglas J. Taatjes
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 17:3294-3301
Abstract Plasminogen activators (PAs) and their inhibitor, plasminogen activator inhibitor type-1 (PAI-1), have been implicated in modulation of luminal fibrinolysis and mural proteolysis contributing to atherogenesis. Expression of PAs/PAI-1 (normal
Publikováno v:
Journal of Cellular Biochemistry. 61:9-17
We report here that the antiestrogen tamoxifen (TAM) induces cell death in human breast cancer cell line MCF-7. We assessed the type of cell death induced by TAM in this breast cancer cell line on the basis of morphological and biochemical characteri
Publikováno v:
Methods in Cell Science. 17:245-249
The development of methods to culture intact viable tissue is integral to understanding mechanisms of disease. Mature lung tissue, in particular, is difficult to maintain for any extended period of time in culture due to collapse of airspaces and rap
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 267:L720-L727
Elevated fractions of inspired O2 induce significant remodeling of the airways and vasculature of the lung. The present study was undertaken to determine the direct effects of altered levels of O2 on protein synthesis and cell proliferation in lung t
Autor:
Paul J. A. Borm, Yvonne M. W. Janssen, E. Gabrielson, Marlene Absher, Kevin E. Driscoll, Brooke T. Mossman, Joanne P. Marsh
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 149:795-802
The generation of oxidants is a proposed mechanism of cell injury by asbestos fibers. To determine whether human pleural mesothelial cells (HMC) respond to asbestos and active oxygen species (AOS) by induction of antioxidant enzymes, cells obtained f