Zobrazeno 1 - 10
of 236
pro vyhledávání: '"MARKUS AEBI"'
Autor:
Ana S. Ramírez, Mario de Capitani, Giorgio Pesciullesi, Julia Kowal, Joël S. Bloch, Rossitza N. Irobalieva, Jean-Louis Reymond, Markus Aebi, Kaspar P. Locher
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Oligosaccharyltransferase (OST), the central enzyme in N-glycosylation, modifies acceptor proteins by attaching a complex glycan. Cryo-EM structures of OST in distinct states, reveal the molecular basis of substrate recognition and catalysis.
Externí odkaz:
https://doaj.org/article/43b2b3330caf4ca4bdb47a82b87d0d0f
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105417- (2022)
Summary: Glycoprotein processing along a complex highly compartmentalized pathway is a hallmark of eukaryotic cells. We followed the kinetics of intracellular, site-specific glycan processing of a model protein with five distinct N-glycosylation site
Externí odkaz:
https://doaj.org/article/88ba732ce9b345d58c74d83cbcaf2c2e
Autor:
Hanne L. P. Tytgat, Chia-wei Lin, Mikail D. Levasseur, Markus B. Tomek, Christoph Rutschmann, Jacqueline Mock, Nora Liebscher, Naohiro Terasaka, Yusuke Azuma, Michael Wetter, Martin F. Bachmann, Donald Hilvert, Markus Aebi, Timothy G. Keys
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Established bacterial glycoengineering platforms limit access to protein and glycan substrates. Here the authors design a cytoplasmic protein glycosylation system, Glycoli, to generate a variety of multivalent glycostructures.
Externí odkaz:
https://doaj.org/article/ac3f91e741e14ae68b947f045f6333f3
Autor:
Paul Schmid-Hempel, Markus Aebi, Seth Barribeau, Toshihiko Kitajima, Louis du Plessis, Regula Schmid-Hempel, Stefan Zoller
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0189738 (2018)
Trypanosomatids (Trypanosomatidae, Kinetoplastida) are flagellated protozoa containing many parasites of medical or agricultural importance. Among those, Crithidia bombi and C. expoeki, are common parasites in bumble bees around the world, and phylog
Externí odkaz:
https://doaj.org/article/eb1a094acadf43edb0ffa209e3d74e2e
Autor:
Christian Heim, Hubertus Hertzberg, Alex Butschi, Silvia Bleuler-Martinez, Markus Aebi, Peter Deplazes, Markus Künzler, Saša Štefanić
Publikováno v:
Parasites & Vectors, Vol 8, Iss 1, Pp 1-10 (2015)
Abstract Background Lectins are carbohydrate-binding proteins that are involved in fundamental intra- and extracellular biological processes. They occur ubiquitously in nature and are especially abundant in plants and fungi. It has been well establis
Externí odkaz:
https://doaj.org/article/03ed9bbc2f16492fb542dff598a9a98e
Autor:
Jon Cuccui, Vanessa S. Terra, Janine T. Bossé, Andreas Naegeli, Sherif Abouelhadid, Yanwen Li, Chia-Wei Lin, Prerna Vohra, Alexander W. Tucker, Andrew N. Rycroft, Duncan J. Maskell, Markus Aebi, Paul R. Langford, Brendan W. Wren
Publikováno v:
Open Biology, Vol 7, Iss 1 (2017)
Actinobacillus pleuropneumoniae is a mucosal respiratory pathogen causing contagious porcine pleuropneumonia. Pathogenesis studies have demonstrated a major role for the capsule, exotoxins and outer membrane proteins. Actinobacillus pleuropneumoniae
Externí odkaz:
https://doaj.org/article/de80ff705bc54df896c39f112a768b9f
Autor:
Joao A Rodrigues, Alvaro Acosta-Serrano, Markus Aebi, Michael A J Ferguson, Françoise H Routier, Irene Schiller, Simão Soares, Daniel Spencer, Alexander Titz, Iain B H Wilson, Luis Izquierdo
Publikováno v:
PLoS Pathogens, Vol 11, Iss 11, p e1005169 (2015)
Externí odkaz:
https://doaj.org/article/c0085006c08b41e19aba1a772fc8b837
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129381 (2015)
Lectins are non-immunoglobulin carbohydrate-binding proteins without enzymatic activity towards the bound carbohydrates. Many lectins of e.g. plants or fungi have been suggested to act as toxins to defend the host against predators and parasites. We
Externí odkaz:
https://doaj.org/article/d14fef644d2745c9a1b804f96b0aab88
Autor:
Mario Schubert, Silvia Bleuler-Martinez, Alex Butschi, Martin A. Wälti, Pascal Egloff, Katrin Stutz, Shi Yan, Mayeul Collot, Jean-Maurice Mallet, Iain B. H. Wilson, Michael O. Hengartner, Markus Aebi, Frédéric H.-T. Allain, Markus Künzler
Publikováno v:
PLoS Pathogens, Vol 8, Iss 8 (2012)
Externí odkaz:
https://doaj.org/article/c0c170b59efc4fe98329ef68d86e3dd4
Autor:
Mario Schubert, Silvia Bleuler-Martinez, Alex Butschi, Martin A Wälti, Pascal Egloff, Katrin Stutz, Shi Yan, Mayeul Collot, Jean-Maurice Mallet, Iain B H Wilson, Michael O Hengartner, Markus Aebi, Frédéric H-T Allain, Markus Künzler
Publikováno v:
PLoS Pathogens, Vol 8, Iss 5, p e1002706 (2012)
Discrimination between self and non-self is a prerequisite for any defence mechanism; in innate defence, this discrimination is often mediated by lectins recognizing non-self carbohydrate structures and so relies on an arsenal of host lectins with di
Externí odkaz:
https://doaj.org/article/45c7d5b3702e41178f59d545fd19aa0b