Výsledky vyhledávání - "MARK O. M. TSO"

Activation of nuclear factor-kappaB during retinal degeneration in rd mice

Autor: Hui-Yang, Zeng, Mark O M, Tso, Shenghan, Lai, Hong, Lai

Publikováno v: Molecular Vision

Transcription factors of the nuclear factor-kappa beta (NF-kappaB) family have been demonstrated to play an important role in the regulation of gene expression in the chronic neurodegenerative disorders. The aims of the current study were to investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1b04cf1bb174197547ecdb4f351edd6e
https://pubmed.ncbi.nlm.nih.gov/18552981

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Differentiation of rabbit bone marrow mesenchymal stem cells into corneal epithelial cells in vivo and ex vivo

Autor: Shaofeng, Gu, Chengzhong, Xing, Jingyi, Han, Mark O M, Tso, Jing, Hong

Publikováno v: Molecular Vision

Purpose To examine whether bone marrow mesenchymal stem cells (MSCs) could be differentiated into corneal epithelial cells in vivo and ex vivo. Methods In vivo, BrdU labeled rabbit MSCs (Rb-MSCs) were suspended in the fibrin gels and transplanted ont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c52632f9ec5c51633f050436ba81aa62
https://pubmed.ncbi.nlm.nih.gov/19156227

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[Pathological study of retinal excitotoxicity following subretinal injection of NMDA]

Autor: Chun, Zhang, Yong-Sheng, Xu, Wei, Wang, Mark O M, Tso

Publikováno v: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology. 43(10)

To study neuronal excitotoxicity induced by subretinal injection of glutamate analogues.We injected 30 mmol/L N-methyl-D-aspartate (NMDA) in 10 microl of DMEM/F12 into subretinal blebs in 24 one-month-old rabbits that were killed 0.5, 1, 2 or 7 days

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a4bb323e84779846848b5f2044e5ea2b
https://pubmed.ncbi.nlm.nih.gov/18201531

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Minocycline and sulforaphane inhibited lipopolysaccharide-mediated retinal microglial activation

Autor: Li-ping, Yang, Xiu-an, Zhu, Mark O M, Tso

Publikováno v: Molecular Vision

Purpose To elucidate the inhibitory effect of minocycline and sulforaphane on lipopolysaccharide (LPS)-induced retinal microglial activation and the mechanisms through which they exerted their inhibitory effects. Methods Primary retinal microglial cu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e2fb064df14d32747703dbf5890c05d5
https://pubmed.ncbi.nlm.nih.gov/17653053

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A possible mechanism of microglia-photoreceptor crosstalk

Autor: Li-ping, Yang, Xiu-an, Zhu, Mark O M, Tso

Publikováno v: Molecular vision. 13

The goal of this study was to explore the relationship between photoreceptor apoptosis and retinal microglial activation.A murine photoreceptor cell line (661W cells) was exposed to LPS-treated microglial cell conditioned medium (MGCM), and cell viab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f41e881a3a7a79d4cf5344cc05efe927
https://pubmed.ncbi.nlm.nih.gov/18079678

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Preface

Autor: MARK O. M. TSO, MORTON F. GOLDBERG, GORDON GUND

Publikováno v: Retina (Philadelphia, Pa.). 25

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e782087c25081062faefd304da6f86c2
https://pubmed.ncbi.nlm.nih.gov/16374307

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Activation of microglia and chemokines in light-induced retinal degeneration

Autor: Cheng, Zhang, Ji-Kui, Shen, Tim T, Lam, Hui-Yang, Zeng, Samuel K, Chiang, Fang, Yang, Mark O M, Tso

Publikováno v: Molecular vision. 11

Microglial cells, which are activated and recruited by chemokines, have been shown to play crucial roles in neuronal degenerations of the central nervous system (CNS). This study investigated the activation and migration of retinal microglial cells a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fb60257eddb6f085318e04cd046b3a33
https://pubmed.ncbi.nlm.nih.gov/16270028

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NF-kappaB activation in light-induced retinal degeneration in a mouse model

Autor: Tinghuai, Wu, Yueguo, Chen, Samuel K S, Chiang, Mark O M, Tso

Publikováno v: Investigative ophthalmologyvisual science. 43(9)

To investigate the modulation of nuclear factor (NF)-kappaB in light-induced photoreceptor degeneration in a mouse model.Mice were exposed to intense green light. Light-induced activation of NF-kappaB and its nuclear localization were studied by immu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cd9575e7fa36f7e78374a293536210cf
https://pubmed.ncbi.nlm.nih.gov/12202499

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