Zobrazeno 1 - 10
of 1 593
pro vyhledávání: '"MARK A. BROWN"'
Publikováno v:
IEEE Access, Vol 12, Pp 156980-156993 (2024)
The North Pacific (NOPAC) oceanic airspace has a high traffic demand between Asia and North America, and its capacity is limited by the non-radar air traffic control environment. Improvements in satellite-based navigation and datalink services have r
Externí odkaz:
https://doaj.org/article/c24e3fa7e09942419a19f8ae9797d631
Autor:
Mark A. Brown
Publikováno v:
Jornal de Pediatria, Vol 98, Iss 6, Pp 548-550 (2022)
Externí odkaz:
https://doaj.org/article/73632d5aa8e8471282575edbf6931f49
Autor:
Chris Rossiter, Amanda Henry, Lynne Roberts, Mark A. Brown, Megan Gow, Clare Arnott, Justine Salisbury, Annette Ruhotas, Angela Hehir, Elizabeth Denney-Wilson
Publikováno v:
BMC Public Health, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Hypertensive disorders of pregnancy have longer-term implications, increasing women’s lifetime cardiovascular disease risk. The Blood Pressure Postpartum study is a multi-centre randomised three-arm trial of interventions, rangi
Externí odkaz:
https://doaj.org/article/2c17a88413b242d1995139d10ad09886
Publikováno v:
Atherosclerosis Plus, Vol 48, Iss , Pp 12-19 (2022)
Background and aims: Preeclampsia (PE) is associated with life-long increased risk of cardiovascular disease. One of the main protective functions of high-density lipoprotein (HDL) is its role in reverse cholesterol transport. HDL-mediated cholestero
Externí odkaz:
https://doaj.org/article/b936d1d76a464a6fa05c082ac9233b60
Autor:
Li Zhu, Mark A. Brown, Robert J. Sims, Gayatri R. Tiwari, Hui Nie, R. Dayne Mayfield, Haley O. Tucker
Publikováno v:
Cells, Vol 12, Iss 13, p 1695 (2023)
The SMYD family is a unique class of lysine methyltransferases (KMTases) whose catalytic SET domain is split by a MYND domain. Among these, Smyd1 was identified as a heart- and skeletal muscle-specific KMTase and is essential for cardiogenesis and sk
Externí odkaz:
https://doaj.org/article/ffb17e4a2a0941e0ac7a6678931a78e4
Autor:
Alyssa Padilla, John F. Manganaro, Lydia Huesgen, Deborah A. Roess, Mark A. Brown, Debbie C. Crans
Publikováno v:
Molecules, Vol 28, Iss 4, p 2000 (2023)
A comprehensive understanding of the mechanisms involved in epigenetic changes in gene expression is essential to the clinical management of diseases linked to the SMYD family of lysine methyltransferases. The five known SMYD enzymes catalyze the tra
Externí odkaz:
https://doaj.org/article/149947d833f44e029be0cb409b1b31c7
Autor:
Mark A. Brown, Lynne Roberts, Anna Hoffman, Amanda Henry, George Mangos, Anthony O’Sullivan, Franziska Pettit, George Youssef, Lily Xu, Gregory K. Davis
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 22 (2020)
Background There is increased risk of hypertension, early cardiovascular disease, and premature mortality in women who have had preeclampsia. This study was undertaken to determine the upper limit of normal blood pressure (BP) 6 months postpartum and
Externí odkaz:
https://doaj.org/article/fcef2c03028e4cfe92fb8a08833cc2d3
Publikováno v:
Diseases, Vol 10, Iss 1, p 4 (2021)
Lysine methylation is among the key posttranslational modifications to histones that contribute to epigenetic regulation. SMYD3 is a lysine methyltransferase that is essential for the proliferation of a range of tumorigenic cells. The findings that S
Externí odkaz:
https://doaj.org/article/24f366ac3a3240de804881e1d0d95e60
Anticancer Impact of Nitric Oxide (NO) and NO Combination with SMYD-3 Inhibitor on Breast Carcinomas
Publikováno v:
Diseases, Vol 9, Iss 4, p 82 (2021)
Despite enormous advances in the detection and treatment of breast cancer, it still remains the leading cancer diagnosis and has the second highest mortality rate. Thus, breast cancer research is a high priority for academics and clinicians alike. Ba
Externí odkaz:
https://doaj.org/article/f2e0ab54dd194d20911732e59b1f7fc1
Publikováno v:
Diseases, Vol 9, Iss 1, p 12 (2021)
With the approval and distribution of demonstrably safe COVID-19 vaccines bearing exceptionally high efficacy profiles, it may be tempting to envision a return to “normal” in the coming months. However, if there is one lesson to be learned from t
Externí odkaz:
https://doaj.org/article/a013d43755984433b564262b793220ec