Zobrazeno 1 - 10 of 12 pro vyhledávání: '"MARIO M. MANGINO"'
1
Stimulation of DNA Synthesis in Pancreatic Duct Cells by Gastrointestinal Hormones
Autor: Dante G. Scarpelli, Susan C. Hubchak, Mario M. Mangino
Publikováno v: Pancreas. 7:271-279
Pancreatic duct cells of the Syrian hamster were grown as monolayers on thin layers of type I collagen coated onto microporous membranes. The effects of a number of potential trophic factors were tested by their ability to increase [3H]thymidine inco
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf1ea39cb890e0a270901d4f8db478a
https://doi.org/10.1097/00006676-199205000-00002
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2
In vitro carcinogenesis of hamster pancreatic duct cells: cellular and molecular alterations
Autor: Dante G. Scarpelli, S. Laconi, Susan C. Hubchak, Kathy A. Mangold, Mario M. Mangino
Publikováno v: Carcinogenesis. 15(9)
Neoplastic transformation of Syrian golden hamster (SGH) pancreatic duct cells was induced by in vitro treatment with the direct-acting carcinogens N-methylnitrosourea (MNU) and N-(2-hydroxypropyl)nitrosourea (HPNU), with subsequent selection by sust
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fcd967b73501e3adac6e4776bfc015e
https://pubmed.ncbi.nlm.nih.gov/7923593
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3
Characterization of differentiated Syrian golden hamster pancreatic duct cells maintained in extended monolayer culture
Autor: Dante G. Scarpelli, Susan C. Hubchak, Mario M. Mangino, M. K. Reddy
Publikováno v: In vitro cellulardevelopmental biology : journal of the Tissue Culture Association. 26(9)
Epithelial cells isolated from fragments of hamster pancreas interlobular ducts were freed of fibroblast contamination by plating them on air-dried collagen, maintaining them in serum-free Dulbecco's modified Eagle's (DME):F12 medium suppleneted with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a390836e986926d96a162c624d42c7eb
https://pubmed.ncbi.nlm.nih.gov/2121705
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4
Metabolism and activation of the pancreatic carcinogen N-nitrosobis(2-oxopropyl)amine by isolated hepatocytes and pancreatic cells of the Syrian hamster
Autor: Mario M. Mangino, Demetrius M. Kokkinakis, Dante G. Scarpelli
Publikováno v: Carcinogenesis. 11(4)
The metabolism of the pancreatic carcinogen N-nitroso-bis(2-oxopropyl)amine (BOP) was studied using primary hepatocytes and acinar and duct cells isolated from Syrian hamsters. Metabolic activation of BOP was verified by detecting its conversion to C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b701f33294e2447c01d2c2241f116c05
https://pubmed.ncbi.nlm.nih.gov/2108819
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6
Uptake of N-nitrosobis(2-oxopropyl)amine by isolated rat and hamster hepatocytes: species differences and evidence for an active carrier-mediated transport process
Autor: Paul F. Hollenberg, Dante G. Scarpelli, Mario M. Mangino
Publikováno v: Carcinogenesis. 9:1763-1772
The rates of uptake of the carcinogen N-nitrosobis(2-oxopropyl)amine (BOP) by hepatocytes isolated from Fischer rats and Syrian hamsters were determined in order to investigate species differences in cellular transport of the carcinogen. Initial rate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8b3e901c3d7c69421ddd2256a6c74d8
https://doi.org/10.1093/carcin/9.10.1763
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7
An in vitro demonstration of peroxisome proliferation and increase in peroxisomal β-oxidation system mRNAs in cultured rat hepatocytes treated with ciprofibrate
Autor: M. I. Usman, Mario M. Mangino, Keith Alvares, Shobha Thangada, Janardan K. Reddy, M. Sambasiva Rao
Publikováno v: FEBS Letters. (2):205-210
Using the normal adult rat hepatocytes, plated on rat tail collagen-coated dishes and fed a chemically defined medium, we demonstrate here that ciprofibrate at 0.1 mM concentration, increases significantly the mRNA levels of fatty acyl-CoA oxidase, e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffa9b2c6d66879a5e017eb6d223ac59
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8
Formation ofN-Nitrosodimethylamine in Direct-Fire Dried Malt
Autor: Mario M. Mangino, Richard A. Scanlan
Publikováno v: Journal of the American Society of Brewing Chemists. 40:55-57
The principal objective of this work was to investigate the formation and establish the identity of amine precursors for N-nitrosodimethylamine (NDMA) in direct-fire dried malt. NDMA levels in malt...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::16a165fb2ad6838bf634cce9ddbf0bd0
https://doi.org/10.1094/asbcj-40-0055
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10
The effect of 3-methyl substitution on the carcinogenicity of nitroso-4-piperidone
Autor: George M. Singer, William Lijinsky, Mario M. Mangino, Melvin D. Reuber
Publikováno v: Carcinogenesis. 5(10)
The carcinogenic activity of the 3-methyl derivative of nitroso-4-piperidone was compared with that of the compound without the methyl group, by chronic administration to rats at equimolar doses in drinking water. Nitrosopiperidone induced both liver
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e18bc9cf6b1dd16c133e725f8eda4e14
https://pubmed.ncbi.nlm.nih.gov/6488456
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