Zobrazeno 1 - 10
of 92
pro vyhledávání: '"MARIE CHIA-MI LIN"'
Autor:
Tao Li, Ling Liu, Li Li, Xiaoxuan Yao, Xiaoyuan Hu, Jiaxing Cheng, Zhenpu Chen, Jiyin Guo, Ruilei Li, Chunlei Ge, Marie Chia-Mi Lin, Hong Yao
Publikováno v:
Pharmaceuticals, Vol 17, Iss 5, p 645 (2024)
The combination of anti-angiogenesis agents with immune-checkpoint inhibitors is a promising treatment for patients with advanced hepatocellular carcinoma (HCC); however, therapeutic resistance caused by cancer stem cells present in tumor microenviro
Externí odkaz:
https://doaj.org/article/39c7925347484408ac579a0a5ecafcf5
Autor:
Ying Zhu, Kun-Bin Ke, Zhong-Kun Xia, Hong-Jian Li, Rong Su, Chao Dong, Feng-Mei Zhou, Lin Wang, Rong Chen, Shi-Guo Wu, Hui Zhao, Peng Gu, Kwong-Sak Leung, Man-Hon Wong, Gang Lu, Jian-Ying Zhang, Bing-Hua Jiang, Jian-Ge Qiu, Xi-Nan Shi, Marie Chia-mi Lin
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-14 (2021)
Abstract Background Cyclin-dependent kinases 2/4/6 (CDK2/4/6) play critical roles in cell cycle progression, and their deregulations are hallmarks of hepatocellular carcinoma (HCC). Methods We used the combination of computational and experimental ap
Externí odkaz:
https://doaj.org/article/b3feca6eb5344562a341b0a3a071e3bd
Autor:
Zhong-Kun Xia, Wei Wang, Jian-Ge Qiu, Xi-Nan Shi, Hong-Jian Li, Rong Chen, Kun-Bin Ke, Chao Dong, Ying Zhu, Shi-Guo Wu, Rong-Ping Zhang, Zhuo-Ran Meng, Hui Zhao, Peng Gu, Kwong-Sak Leung, Man-Hon Wong, Xiao-Dong Liu, Feng-Mei Zhou, Jian-Ying Zhang, Ya-Ting Yao, Si-Jia Wang, Chun-Yang Zhang, Yan-Ru Qin, Marie Chia-mi Lin, Bing-Hua Jiang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Hepatocellular carcinoma (HCC) is a lethal malignancy lacking effective treatment. The Cyclin-dependent kinases 4/6 (CDK4/6) and PI3K/AKT signal pathways play pivotal roles in carcinogenesis and are promising therapeutic targets for HCC.
Externí odkaz:
https://doaj.org/article/8c577fa7534e405a9a6ce01a297274b9
Autor:
Yanfen Niu, Hongjian Li, Lihui Gao, Hua Lin, Hsiangfu Kung, Marie Chia-mi Lin, Kwong-Sak Leung, Man-Hon Wong, Wenyong Xiong, Ling Li
Publikováno v:
Journal of Pharmacological Sciences, Vol 135, Iss 3, Pp 114-120 (2017)
Hyperuricemia, a long-term purine metabolic disorder, is a well-known risk factor for gout, hypertension and diabetes. In maintaining normal whole-body purine levels, xanthine oxidase (XOD) is a key enzyme in the purine metabolic pathway, as it catal
Externí odkaz:
https://doaj.org/article/a2e4b00442434c1593bc9b2f400d7e6a
Autor:
Jian-Ge Qiu, Lin Wang, Wen-Jing Liu, Ju-Feng Wang, Er-Jiang Zhao, Feng-Mei Zhou, Xiang-Bo Ji, Li-Hong Wang, Zhong-Kun Xia, Wei Wang, Marie Chia-mi Lin, Ling-Zhi Liu, Ying-Xue Huang, Bing-Hua Jiang
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Esophagus cancer is the seventh cause of cancer-related deaths globally. In this study, we analyzed interleukin 6 (IL-6) gene expression in human esophagus cancer patients and showed that IL-6 mRNA levels are significantly higher in tumor tissues and
Externí odkaz:
https://doaj.org/article/801eb00213ac46469bd9668cec839df0
Autor:
Yan-xin Ren, Jun Sui, Xin Song, Gee Wan Wong, Jing Ma, Hong Yao, Marie Chia-mi Lin, Xiao-jiang Li
Publikováno v:
Cancer Biology & Medicine, Vol 8, Iss 2, Pp 106-113 (2011)
OBJECTIVE CD4 CD25 T regulatory (Treg) cells are a population of T cells which suppress an overactive immune system. CCR4 is a chemokine receptor involved in the recruitment of lymphocytes. Nasopharyngeal carcinoma (NPC) is resistant to immunosurveil
Externí odkaz:
https://doaj.org/article/99f9ef20bc3f4364a227ad009e67b879
Autor:
Xi-Nan Shi, Hongjian Li, Hong Yao, Xu Liu, Ling Li, Kwong-Sak Leung, Hsiang-fu Kung, Di Lu, Man-Hon Wong, Marie Chia-mi Lin
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132072 (2015)
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide. Surgical resection and conventional chemotherapy and radiotherapy ultimately fail due to tumor recurrence and HCC's resistance. The development of novel t
Externí odkaz:
https://doaj.org/article/502d622cdedb4e349c393ff4291c3b59
Autor:
Kunbin Ke, Peng Gu, Yin Chen, Hongjian Li, Zhengchao Shen, Marie Chia‐mi Lin, Rongping Zhang, Zhenhua Gao, Xinan Shi
Publikováno v:
ChemistrySelect. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e251f0c8e71582118c9df05f4bdef2a6
https://doi.org/10.1002/slct.202200424
https://doi.org/10.1002/slct.202200424
Autor:
Yi Yang, Ceshi Chen, Kunbin Ke, Hongjian Li, Chao Dong, Xu Liu, Jing Ma, Ling Li, Marie Chia-mi Lin, Hsiang-Fu Kung, Yin Chen, Hongtao Zhang, Xi-Nan Shi
Publikováno v:
International Journal of Biological Sciences
Background: The phosphatidylinositol 3-kinase (PI3K)/AKT signaling pathway is hyperactivated in lung cancer and regulates a broad range of cellular processes, including proliferation, survival, angiogenesis, and metastasis. Thus PI3K is considered a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ee8731cad0b227352f654a1a8f7306
http://europepmc.org/articles/PMC6643147
http://europepmc.org/articles/PMC6643147
Autor:
Ying Zhu, Kun-Bin Ke, Zhong-Kun Xia, Hong-Jian Li, Rong Su, Chao Dong, Feng-Mei Zhou, Lin Wang, Rong Chen, Shi-Guo Wu, Hui Zhao, Peng Gu, Kwong-Sak Leung, Man-Hon Wong, Gang Lu, Jian-Ying Zhang, Bing-Hua Jiang, Jian-Ge Qiu, Xi-Nan Shi, Marie Chia-mi Lin
Background: Cyclin-dependent kinases 2/4/6 (CDK2/4/6) play critical roles in cell cycle progression, and their deregulations are hallmarks of hepatocellular carcinoma (HCC). Methods: We used the combination of computational and experimental approache
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d6455aec1d43e159509b3cbc132d94c
https://doi.org/10.21203/rs.3.rs-29276/v3
https://doi.org/10.21203/rs.3.rs-29276/v3
