Zobrazeno 1 - 10
of 37
pro vyhledávání: '"MARIA JIMENEZ GONZALEZ"'
Autor:
Alexandra Alvarsson, Maria Jimenez-Gonzalez, Rosemary Li, Carolina Rosselot, Nikolaos Tzavaras, Zhuhao Wu, Sarah Stanley
Publikováno v:
Bio-Protocol, Vol 11, Iss 15 (2021)
The pancreas is a heavily innervated organ, but pancreatic innervation can be challenging to comprehensively assess using conventional histological methods. However, recent advances in whole-mount tissue clearing and 3D rendering techniques have allo
Externí odkaz:
https://doaj.org/article/6859ab640ac44afda26fcce548d61852
Autor:
Mitchell Bayne, Alexandra Alvarsson, Kavya Devarakonda, Rosemary Li, Maria Jimenez-Gonzalez, Darline Garibay, Kaetlyn Conner, Merina Varghese, Madhavika N. Serasinghe, Jerry E. Chipuk, Patrick R. Hof, Sarah A. Stanley
Publikováno v:
JCI Insight, Vol 5, Iss 21 (2020)
Hypoglycemia is a frequent complication of diabetes, limiting therapy and increasing morbidity and mortality. With recurrent hypoglycemia, the counterregulatory response (CRR) to decreased blood glucose is blunted, resulting in hypoglycemia-associate
Externí odkaz:
https://doaj.org/article/23aab8c66b19432ca7e406bd9e534a7b
Autor:
ROLLIE F. HAMPTON, ALEXANDRA ALVARSSON, MARIA JIMENEZ GONZALEZ, ROSEMARY Y. LI, KAVYA DEVARAKONDA, SARAH STANLEY
Publikováno v:
Diabetes. 71
Background: Pancreatic islets are richly innervated. Use of 2D immunohistochemistry and extreme models of obesity and diabetes have limited our understanding of pancreatic nerve anatomy. Additionally, our knowledge of the direct roles of pancreatic n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b6cbeb5893abab1b10a3b2e29e59cd2
https://doi.org/10.2337/db22-1388-p
https://doi.org/10.2337/db22-1388-p
Autor:
KAVYA DEVARAKONDA, RICAHRD O’CONNOR, ALEXANDRA ALVARSSON, ROSEMARY Y. LI, MARIA JIMENEZ GONZALEZ, PAUL KENNY, SARAH STANLEY
Publikováno v:
Diabetes. 71
Neural signals play a critical role in metabolic regulation by controlling behavior and coordinating glucose production and uptake in peripheral organs. Physiological and psychological stimuli that disrupt homeostasis - stressors - result in metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6ba53983af9d593c0db2b093ff26ba8
https://doi.org/10.2337/db22-1308-p
https://doi.org/10.2337/db22-1308-p
Autor:
Maria Jimenez Gonzalez, Rosemary Li, Lisa E. Pomeranz, Alexandra Alvarsson, Roberta Marongiu, Rollie F. Hampton, Rupangi C. Vasavada, Gary J. Schwartz, Sarah A. Stanley
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a623a933e57e96a444563d712b17177
https://doi.org/10.1096/fasebj.2022.36.s1.r2070
https://doi.org/10.1096/fasebj.2022.36.s1.r2070
Publikováno v:
Diabetologia
The central and peripheral nervous systems play critical roles in regulating pancreatic islet function and glucose metabolism. Over the last century, in vitro and in vivo studies along with examination of human pancreas samples have revealed the stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574cff37929637a842aa529d3566a88b
https://pubmed.ncbi.nlm.nih.gov/35348820
https://pubmed.ncbi.nlm.nih.gov/35348820
Autor:
Zhuhao Wu, Rosemary Li, Maria Jimenez-Gonzalez, Nikolaos Tzavaras, Carolina Rosselot, Alexandra Alvarsson, Sarah A. Stanley
Publikováno v:
Bio Protoc
The pancreas is a heavily innervated organ, but pancreatic innervation can be challenging to comprehensively assess using conventional histological methods. However, recent advances in whole-mount tissue clearing and 3D rendering techniques have allo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcedb6389306855b09d28c3dc9f2752f
https://europepmc.org/articles/PMC8376577/
https://europepmc.org/articles/PMC8376577/
Publikováno v:
Diabetes. 70
There is substantial evidence that neural regulation plays a critical role in glucose metabolism and hormone release. Targeting neural populations innervating the pancreas could provide an alternative therapy for diabetes. However, our understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5593fbfd9c7ce4fc57467ce199532d01
https://doi.org/10.2337/db21-169-or
https://doi.org/10.2337/db21-169-or
Autor:
Alexandra Alvarsson, Vanessa E. Lehmann, Rosemary Li, Kavya Devarakonda, Maria Jimenez Gonzalez, Sarah Stanley
Publikováno v:
Diabetes. 70
Medial amygdala projections regulate the metabolic responses to internal and external signals The brain is a crucial part of the complex system that controls blood glucose in response to internal signals and external stressors. However, we do not kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e455a5bd05fc09bbc401247119999a7
https://doi.org/10.2337/db21-173-or
https://doi.org/10.2337/db21-173-or
Autor:
Andrew F. Stewart, Nikolaos Tzavaras, Rosemary Li, Adolfo Garcia-Ocaña, Sarah A. Stanley, Maria Jimenez-Gonzalez, Alexandra Alvarsson, Zhuhao Wu, Carolina Rosselot
Publikováno v:
Science Advances
Three-dimensional mapping of pancreatic innervation shows rapid remodeling of islet innervation in mouse and human diabetes.
Understanding the detailed anatomy of the endocrine pancreas, its innervation, and the remodeling that occurs in diabete
Understanding the detailed anatomy of the endocrine pancreas, its innervation, and the remodeling that occurs in diabete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b047fd61ae7f04d61182a6ab760fd2f8
https://doi.org/10.1126/sciadv.aaz9124
https://doi.org/10.1126/sciadv.aaz9124