Zobrazeno 1 - 10
of 155
pro vyhledávání: '"MARIA CRISTINA BRESCHI"'
Autor:
Stefano Fogli, Beatrice Polini, Sara Carpi, Barbara Pardini, Alessio Naccarati, Nevio Dubbini, Maria Lanza, Maria Cristina Breschi, Antonella Romanini, Paola Nieri
Publikováno v:
Tumor Biology, Vol 39 (2017)
Melanoma is a devastating disease with few therapeutic options in the advanced stage and with the urgent need of reliable biomarkers for early detection. In this context, circulating microRNAs are raising great interest as diagnostic biomarkers. We a
Externí odkaz:
https://doaj.org/article/01223533363745869829303b11368e67
Autor:
Sara Carpi, Stefano Fogli, Ambra Giannetti, Barbara Adinolfi, Sara Tombelli, Eleonora Da Pozzo, Alessia Vanni, Enrica Martinotti, Claudia Martini, Maria Cristina Breschi, Mario Pellegrino, Paola Nieri, Francesco Baldini
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114588 (2014)
Survivin is an inhibitor of apoptosis overexpressed in different types of tumors and undetectable in most terminally differentiated normal tissues. In the current study, we sought to evaluate the in vitro theranostic properties of a molecular beacon-
Externí odkaz:
https://doaj.org/article/3b6fcd5afb554c4da94b897e90dc435b
Autor:
Sara Carpi, Adriano Podestà, Beatrice Polini, Antonella Romanini, Maria Cristina Breschi, Paola Nieri
Publikováno v:
Pigment Cell & Melanoma Research. 32:486-499
Cutaneous melanoma is a skin cancer with increasing incidence. Identification of novel clinical biomarkers able to detect the stage of disease and suggest prognosis could improve treatment and outcome for melanoma patients. Cell-free microRNAs (cf-mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611a0f89e044f509d653c9c06f78ee2c
https://doi.org/10.1111/pcmr.12755
https://doi.org/10.1111/pcmr.12755
Autor:
Eleonora Pagnotta, Lara Testai, Luisa Ugolini, Onorina L. Manzo, Mariarosaria Bucci, Lorenzo Di Cesare Mannelli, Eugenia Piragine, Maria Cristina Breschi, Valentina Citi, Luca Lazzeri, Alma Martelli, Carla Ghelardini, Vincenzo Calderone
Publikováno v:
Br J Pharmacol
BACKGROUND AND PURPOSE: Hydrogen sulfide (H(2)S)‐releasing agents are viewed as potential antihypertensive drugs. Recently, natural isothiocyanates emerged as original H(2)S‐donor agents. Among them, erucin, present in some edible cruciferous pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19517afc215364cdb7497729d867ca2
http://hdl.handle.net/11568/990113
http://hdl.handle.net/11568/990113
Publikováno v:
Current Medicinal Chemistry. 25:2661-2674
Background: Mitochondria play a central role in ATP-generating processes. Indeed, in mammalian tissues, up to 90% of ATP is generated by mitochondria through the process of oxidative phosphorylation; furthermore, mitochondria are involved in multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94be79b228c3aa794fe44994fa65b73a
https://doi.org/10.2174/0929867324666171012115300
https://doi.org/10.2174/0929867324666171012115300
Iminothioethers as Hydrogen Sulfide Donors: From the Gasotransmitter Release to the Vascular Effects
Autor:
Eugenia Piragine, Valentina Citi, Federico Da Settimo, Maria Cristina Breschi, Claudia Gargini, Lara Testai, Giulia Nesi, Vincenzo Calderone, Elisabetta Barresi, Ilaria Piano, Alma Martelli, Simona Rapposelli, Sabrina Taliani
Publikováno v:
Journal of Medicinal Chemistry. 60:7512-7523
The gasotransmitter hydrogen sulfide (H2S) is an important tuner of the cardiovascular homeostasis, and its deficiency is etiologically associated with a number of cardiovascular diseases. Therefore, the research of original moieties able to release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::455867f7dd708ee9c453205298638aed
https://doi.org/10.1021/acs.jmedchem.7b00888
https://doi.org/10.1021/acs.jmedchem.7b00888
Autor:
Laura Carrozzi, Marzia Del Re, Ferruccio Aquilini, Antonio Palla, Romano Danesi, Maria Cristina Breschi, Francesco Pistelli, Riccardo Zucchi, Stefano Fogli, Alessandro Saba
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 131:208-213
The nicotine metabolite ratio, i.e., the ratio 3-hydroxycotinine/cotinine, is used to assess the nicotine metabolic status and has been proven to predict the response to smoking cessation treatments in randomized clinical trials. In the current study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d8b1dcb7c9a2a5541c9746e03c6b75
https://doi.org/10.1016/j.jpba.2016.08.041
https://doi.org/10.1016/j.jpba.2016.08.041
Autor:
Vincenzo Calderone, Maria Cristina Breschi, Miren Josune Canduela, Paolo Ambrosino, Alma Martelli, Vincenzo Barrese, Michael J. Curtis, Lara Testai, Maria Josè Sisalli, Iolanda Vinciguerra, Maurizio Taglialatela, Antonella Scorziello, Pedro Grandes, Iain A. Greenwood, Francesco Miceli, Maria Virginia Soldovieri
Publikováno v:
Testai, L, Barrese, V, Soldovieri, M V, Ambrosino, P, Martelli, A, Vinciguerra, I, Miceli, F, Greenwood, I A, Curtis, M J, Breschi, M C, Sisalli, M J, Scorziello, A, Canduela, M J, Grandes, P, Calderone, V & Taglialatela, M 2016, ' Expression and function of Kv7.4 channels in rat cardiac mitochondria : Possible targets for cardioprotection ', Cardiovascular Research, vol. 110, no. 1, pp. 40-50 . https://doi.org/10.1093/cvr/cvv281
Aims: Plasmalemmal Kv7.1 (KCNQ1) channels are critical players in cardiac excitability; however, little is known on the functional role of additional Kv7 family members (Kv7.2-5) in cardiac cells. In this work, the expression, function, cellular and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1beb49437bc118eb1993be9b1087db
https://doi.org/10.1093/cvr/cvv281
https://doi.org/10.1093/cvr/cvv281
Publikováno v:
Expert Opinion on Drug Discovery. 11:163-175
Hydrogen sulfide (H2S) is an endogenous gasotransmitter, involved in the regulation of several biological functions. Conversely, impaired biosynthesis of H2S is associated with important diseases. This paves the way for exciting pharmacological persp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a304d784687e9b754844a44bd3955f8c
https://doi.org/10.1517/17460441.2016.1122590
https://doi.org/10.1517/17460441.2016.1122590
Autor:
Valentina Citi, Eugenia Piragine, Vincenzo Calderone, Maria Cristina Breschi, Alma Martelli, Lara Testai
In the last four decades, the several classes of diuretics, currently available for clinical use, have been the first line option for the therapy of widespread cardiovascular and non-cardiovascular diseases. Diuretic drugs generally exhibit an overal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b68152e7fd80da1e63b60c485fe8dab
http://hdl.handle.net/11568/875140
http://hdl.handle.net/11568/875140