New carbohydrazide derivatives of 1H-pyrazolo[3,4-b]pyridine and trypanocidal activity

Autor: RAQUEL R.S. SALVADOR, MURILO L. BELLO, IGOR R.L. BARRETO, MARIA A.F. VERA, ESTELA M.F. MURI, SÉRGIO DE ALBUQUERQUE, LUIZA R.S. DIAS

Publikováno v: Anais da Academia Brasileira de Ciências, Iss 0

ABSTRACT This paper reports the in vitro trypanocidal activity evaluation of new carbohydrazide derivatives from 3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine, substituted at C-6 position by phenyl, methyl or trifluoromethyl group. These compounds wer

Externí odkaz: https://doaj.org/article/e9ebd4f728da48ed83c5b83a72f04335

Antiplatelet activity and structure-activity relationship study of Pyrazolopyridine Derivatives as potential series for treating thrombotic diseases

Autor: Luiza R.S. Dias, T Nagashima, Marcelo Braga dos Santos, Marcos da Veiga Kalil, Antonio C. C. Freitas, Carlos Rangel Rodrigues, Reinaldo B Geraldo, Magaly Girão Albuquerque, Murilo Lamim Bello, Lucio Mendes Cabral, Maria A.F. Vera, Helena Carla Castro, Paula Alvarez Abreu

Publikováno v: Journal of Atherosclerosis and Thrombosis. 17:730-739

Aim: Platelets plays a central role in hemostatic processes and consequently are similarly involved in pathological processes, such as arterial thrombosis and atherosclerosis. Herein we described the synthesis, antiplatelet profile and structure-acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de230339aea966e6e09a083250c50d36
https://doi.org/10.5551/jat.3293

New carbohydrazide derivatives of 1H-pyrazolo[3,4-b]pyridine and trypanocidal activity

Autor: Luiza R.S. Dias, Sérgio de Albuquerque, Murilo Lamim Bello, Igor Ramon Lomba Barreto, Raquel R.S. Salvador, Estela M.F. Muri, Maria A.F. Vera

Publikováno v: Anais da Academia Brasileira de Ciências, Iss 0
Anais da Academia Brasileira de Ciências, Volume: 88, Issue: 4, Pages: 2341-2348, Published: 01 DEC 2016
Anais da Academia Brasileira de Ciências v.88 n.4 2016
Anais da Academia Brasileira de Ciências
Academia Brasileira de Ciências (ABC)
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This paper reports the in vitro trypanocidal activity evaluation of new carbohydrazide derivatives from 3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine, substituted at C-6 position by phenyl, methyl or trifluoromethyl group. These compounds were evaluat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d1d7dc1cfc40aa4ff9b5ec13a4c3b9
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016005020105&lng=en&tlng=en