Zobrazeno 1 - 10
of 143
pro vyhledávání: '"MARCO T NÚÑEZ"'
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 5, Pp 1003-1004 (2022)
Externí odkaz:
https://doaj.org/article/64556740e85a457bbd95b007af46c14e
Autor:
Olimpo García-Beltrán, Natalia P Mena, Pabla Aguirre, Germán Barriga-González, Antonio Galdámez, Edgar Nagles, Tatiana Adasme, Cecilia Hidalgo, Marco T Núñez
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189043 (2017)
Iron accumulation, oxidative stress and calcium signaling dysregulation are common pathognomonic signs of several neurodegenerative diseases, including Parkinson´s and Alzheimer's diseases, Friedreich ataxia and Huntington's disease. Given their the
Externí odkaz:
https://doaj.org/article/07513b7a3cd840afac3e9920a4d04929
Autor:
Pabla Aguirre, Natalia P Mena, Carlos M Carrasco, Yorka Muñoz, Patricio Pérez-Henríquez, Rodrigo A Morales, Bruce K Cassels, Carolina Méndez-Gálvez, Olimpo García-Beltrán, Christian González-Billault, Marco T Núñez
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144848 (2015)
Neuronal death in Parkinson's disease (PD) is often preceded by axodendritic tree retraction and loss of neuronal functionality. The presence of non-functional but live neurons opens therapeutic possibilities to recover functionality before clinical
Externí odkaz:
https://doaj.org/article/07e3dcd9b356406682ba92db1457d413
Publikováno v:
Biological Research, Vol 39, Iss 1, Pp 113-124 (2006)
Levels of body iron should be tightly controlled to prevent the formation of oxygen radicals, lipoperoxidation, genotoxicity, and the production of cytotoxic cytokines, which result in damage to a number of organs. Enterocytes in the intestinal villa
Externí odkaz:
https://doaj.org/article/a3406fb389c4400aadd13c5ff1afebd9
Publikováno v:
Biological Research, Vol 39, Iss 1, Pp 95-102 (2006)
Interactions of micronutrients can affect absorption and bioavailability of other nutrients by a number of mechanisms. In aqueous solutions, and at higher uptake levels, competition between elements with similar chemical characteristics and uptake pr
Externí odkaz:
https://doaj.org/article/9b4a6d12ec45461db2ec016b2fdae6a3
Publikováno v:
Biological Research, Vol 39, Iss 1, Pp 157-165 (2006)
Neurons, as non-dividing cells, encounter a myriad of stressful conditions throughout their lifespan. In particular, there is increasing evidence that iron progressively accumulates in the brain with age and that iron-induced oxidative stress is the
Externí odkaz:
https://doaj.org/article/a76d43e198904aaba11ecd3bf15ae6cd
Publikováno v:
Biological Research, Vol 39, Iss 1, Pp 191-193 (2006)
Hepcidin (Hepc) is a 25 amino acid cationic peptide with broad antibacterial and antifungal actions. A likely role for Hepc in iron metabolism was suggested by the observation that mice having disruption of the gene encoding the transcription factor
Externí odkaz:
https://doaj.org/article/1bb47e8de4e24c6aa46d2e7f6a3ff8da
Publikováno v:
Biological Research, Vol 39, Iss 1, Pp 189-190 (2006)
Recent evidence suggests that reactive oxygen species function as second messenger molecules in normal physiological processes. For example, activation of N-Methyl-D-Aspartate receptor results in the production of ROS, which appears to be critical fo
Externí odkaz:
https://doaj.org/article/a727cbbef168413f83783811d11858fc
Autor:
MARCO T NÚÑEZ, MICHAEL D GARRICK
Publikováno v:
Biological Research, Vol 39, Iss 1, Pp 5-6 (2006)
Externí odkaz:
https://doaj.org/article/1658654571994e88b2a698b20d19fd7e
Publikováno v:
Antioxidants, Vol 13, Iss 2, p 196 (2024)
Ferroptosis is an iron-dependent cell death pathway that involves the depletion of intracellular glutathione (GSH) levels and iron-mediated lipid peroxidation. Ferroptosis is experimentally caused by the inhibition of the cystine/glutamate antiporter
Externí odkaz:
https://doaj.org/article/adeba5054ea6414aa2cb9afdc4a22958