Zobrazeno 1 - 10
of 203
pro vyhledávání: '"MARC CHADEAU-HYAM"'
Autor:
Marc Chadeau-Hyam, Paolo Vineis, Caroline Relton, Mattias Johansson, Gianluca Severi, Roger L Milne, Melissa C Southey, Pierre-Antoine Dugué, Florence Guida, Mikael Johansson, Torkjel Sandanger, Justina Ucheojor Onwuka, Ryan Langdon, Therese Haugdahl Nøst, Hilary A. Robbins, Matthew Suderman
Publikováno v:
BMJ Oncology, Vol 3, Iss 1 (2024)
Objective Screening high-risk individuals with low-dose CT reduces mortality from lung cancer, but many lung cancers occur in individuals who are not eligible for screening. Risk biomarkers may be useful to refine risk models and improve screening el
Externí odkaz:
https://doaj.org/article/31adadfff44f48119b68988cdec01203
Autor:
Maria Carolina Borges, Gemma L. Clayton, Rachel M. Freathy, Janine F. Felix, Alba Fernández-Sanlés, Ana Gonçalves Soares, Fanny Kilpi, Qian Yang, Rosemary R. C. McEachan, Rebecca C. Richmond, Xueping Liu, Line Skotte, Amaia Irizar, Andrew T. Hattersley, Barbara Bodinier, Denise M. Scholtens, Ellen A. Nohr, Tom A. Bond, M. Geoffrey Hayes, Jane West, Jessica Tyrrell, John Wright, Luigi Bouchard, Mario Murcia, Mariona Bustamante, Marc Chadeau-Hyam, Marjo-Riitta Jarvelin, Martine Vrijheid, Patrice Perron, Per Magnus, Romy Gaillard, Vincent W. V. Jaddoe, William L. Lowe, Bjarke Feenstra, Marie-France Hivert, Thorkild I. A. Sørensen, Siri E. Håberg, Sylvain Serbert, Maria Magnus, Deborah A. Lawlor
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Higher maternal pre-pregnancy body mass index (BMI) is associated with adverse pregnancy and perinatal outcomes. However, whether these associations are causal remains unclear. Methods We explored the relation of maternal pre-/ear
Externí odkaz:
https://doaj.org/article/0a4789dc4d5f4384bda3a38300dc1bb0
Autor:
Christina J. Atchison, Bethan Davies, Emily Cooper, Adam Lound, Matthew Whitaker, Adam Hampshire, Adriana Azor, Christl A. Donnelly, Marc Chadeau-Hyam, Graham S. Cooke, Helen Ward, Paul Elliott
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract The COVID-19 pandemic is having a lasting impact on health and well-being. We compare current self-reported health, quality of life and symptom profiles for people with ongoing symptoms following COVID-19 to those who have never tested posit
Externí odkaz:
https://doaj.org/article/47dd447bfacb4350a0f1ef3faffd497a
Autor:
Jordan Bortz, Andrea Guariglia, Lucija Klaric, David Tang, Peter Ward, Michael Geer, Marc Chadeau-Hyam, Dragana Vuckovic, Peter K. Joshi
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Biological age captures physiological deterioration better than chronological age and is amenable to interventions. Blood-based biomarkers have been identified as suitable candidates for biological age estimation. This study aims to improve
Externí odkaz:
https://doaj.org/article/ba5a4c43f3974dd7a71de8f44d527d75
Autor:
Matthew Whitaker, Bethan Davies, Christina Atchison, Wendy Barclay, Deborah Ashby, Ara Darzi, Steven Riley, Graham Cooke, Christl A. Donnelly, Marc Chadeau-Hyam, Paul Elliott, Helen Ward
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract The value of SARS-CoV-2 lateral flow immunoassay (LFIA) tests for estimating individual disease risk is unclear. The REACT-2 study in England, UK, obtained self-administered SARS-CoV-2 LFIA test results from 361,801 adults in January-May 202
Externí odkaz:
https://doaj.org/article/ad355309c57644ea9659226f453e6bc2
Autor:
Sarah J. Bowden, Triada Doulgeraki, Emmanouil Bouras, Georgios Markozannes, Antonios Athanasiou, Harriet Grout-Smith, Konstantinos S. Kechagias, Laura Burney Ellis, Verena Zuber, Marc Chadeau-Hyam, James M. Flanagan, Konstantinos K. Tsilidis, Ilkka Kalliala, Maria Kyrgiou
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Persistent infection by oncogenic human papillomavirus (HPV) is necessary although not sufficient for development of cervical cancer. Behavioural, environmental, or comorbid exposures may promote or protect against malignant trans
Externí odkaz:
https://doaj.org/article/572c4a8e2f394c4f98069979c8a970fc
Autor:
Khezia Asamoah, Kian Fan Chung, Nazanin Zounemat Kermani, Barbara Bodinier, Sven-Erik Dahlen, Ratko Djukanovic, Pankaj K. Bhavsar, Ian M. Adcock, Dragana Vuckovic, Marc Chadeau-Hyam
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104936- (2024)
Summary: Background: Eosinophilic and neutrophilic asthma defined by high levels of blood and sputum eosinophils and neutrophils exemplifies the inflammatory heterogeneity of asthma, particularly severe asthma. We analysed the serum and sputum proteo
Externí odkaz:
https://doaj.org/article/9d60fe4ea80c4d5ebe54f572eafa9d2e
Autor:
Joseph A. Rothwell, Jelena Bešević, Niki Dimou, Marie Breeur, Neil Murphy, Mazda Jenab, Roland Wedekind, Vivian Viallon, Pietro Ferrari, David Achaintre, Audrey Gicquiau, Sabina Rinaldi, Augustin Scalbert, Inge Huybrechts, Cornelia Prehn, Jerzy Adamski, Amanda J. Cross, Hector Keun, Marc Chadeau-Hyam, Marie-Christine Boutron-Ruault, Kim Overvad, Christina C. Dahm, Therese Haugdahl Nøst, Torkjel M. Sandanger, Guri Skeie, Raul Zamora-Ros, Kostas K. Tsilidis, Fabian Eichelmann, Matthias B. Schulze, Bethany van Guelpen, Linda Vidman, Maria-José Sánchez, Pilar Amiano, Eva Ardanaz, Karl Smith-Byrne, Ruth Travis, Verena Katzke, Rudolf Kaaks, Jeroen W. G. Derksen, Sandra Colorado-Yohar, Rosario Tumino, Bas Bueno-de-Mesquita, Paolo Vineis, Domenico Palli, Fabrizio Pasanisi, Anne Kirstine Eriksen, Anne Tjønneland, Gianluca Severi, Marc J. Gunter
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Amino acid metabolism is dysregulated in colorectal cancer patients; however, it is not clear whether pre-diagnostic levels of amino acids are associated with subsequent risk of colorectal cancer. We investigated circulating level
Externí odkaz:
https://doaj.org/article/56edb90eb305403dba3ccfbb9dabed59
Autor:
Matthew Whitaker, Joshua Elliott, Barbara Bodinier, Wendy Barclay, Helen Ward, Graham Cooke, Christl A. Donnelly, Marc Chadeau-Hyam, Paul Elliott
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
In this study, the authors assess changing symptom profiles associated with different SARS-CoV-2 variants from May 2020 to March 2022 in England. Using data from the REACT-1 study, they find that Omicron infection is more often associated with cold a
Externí odkaz:
https://doaj.org/article/49ef4a4c20114cb6a6311096e7fa0512
Autor:
Marc Chadeau-Hyam, Sudha Sundar, Yasemin Hirst, Hannah R Brewer, James Flanagan, Eric Johnson
Publikováno v:
BMJ Open, Vol 13, Iss 6 (2023)
Objectives Ovarian cancer symptoms are often non-specific and can be normalised before patients seek medical help. The Cancer Loyalty Card Study investigated self-management behaviours of patients with ovarian cancer prior to their diagnosis using lo
Externí odkaz:
https://doaj.org/article/b9b103c5c9e44f4db3396923ce4d98ba