Zobrazeno 1 - 10
of 4 806
pro vyhledávání: '"MAPKs"'
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 10, Pp 916-925 (2024)
Abstract This study aims to investigate the effects of the Galectin‐3 (Gal‐3) inhibitor TD139 on inflammation and the extracellular signal‐regulated kinase (ERK)/c‐Jun N‐terminal kinase (JNK)/p38 pathway in gestational diabetes mellitus (GD
Externí odkaz:
https://doaj.org/article/88cb4030263f4b4e9532d24708230ad7
Publikováno v:
Chemical and Biological Technologies in Agriculture, Vol 11, Iss 1, Pp 1-12 (2024)
Abstract Background Polysaccharides derived from Aralia continentalis Kitagawa possess excellent biological properties, such as anti-tumor, antioxidant, antibacterial, lipid-lowering, and anti-inflammatory. However, the immunomodulatory effects of th
Externí odkaz:
https://doaj.org/article/891f69fc70a14d369945085fb628e16a
Autor:
Francesca Pacifici, Francesca Chiereghin, Michele D’Orazio, Gina Malatesta, Marco Infante, Federica Fazio, Chiara Bertinato, Giulia Donadel, Eugenio Martinelli, Antonino De Lorenzo, David Della-Morte, Donatella Pastore
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 9, Pp 10026-10037 (2024)
Far-Infrared Radiation (FIR) is emerging as a novel non-invasive tool for mitigating inflammation and oxidative stress, offering potential benefits for certain medical conditions such as cardiovascular disease and chronic inflammatory disorders. We p
Externí odkaz:
https://doaj.org/article/f566af53b2084670ac763f717892354d
Publikováno v:
Current Oncology, Vol 31, Iss 9, Pp 4818-4854 (2024)
Invasion and metastasis are important hallmarks of lung cancer, and affect patients’ survival. Early diagnostics of metastatic potential are important for treatment management. Recent findings suggest that the transition to an invasive phenotype ca
Externí odkaz:
https://doaj.org/article/4c28502d147f4f9a844d13a7178a24d2
Autor:
Dilaware Khan, Huakang Zhou, Jinliang You, Vera Annika Kaiser, Rajiv K Khajuria, Sajjad Muhammad
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Smoking is the major cause of cardiovascular diseases and cancer. It induces oxidative stress, leading to DNA damage and cellular senescence. Senescent cells increase the expression and release of pro-inflammatory molecules and matrix metall
Externí odkaz:
https://doaj.org/article/50c59c189e184f72b8a88e40cc22deae
Autor:
Xuenai Wei, Jingrui Song, Qing Rao, Yubing Huang, Qin Liu, Jialei Song, Wei liang, Shuhui Feng, Chen Yan, Yanmei Li
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34115- (2024)
Leukemia is a malignant tumor of the hematologic system. Studies have shown that cernuumolide J (TMJ-105), an extract of Carpesium cernuum, has anti-cancer effects, but the underlying mechanism is unclear. In this study, we investigated the effect of
Externí odkaz:
https://doaj.org/article/c5c26b680ec044e3ae2f74a44ce06870
Autor:
Jia-Qian Zhu, Yuan-Yang Tian, Kam Leung Chan, Zhen Hu, Qing-Qing Xu, Zhi-Xiu Lin, Yan-Fang Xian
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-17 (2024)
Abstract Background Qing-Zao-Jiu-Fei Decoction (QZJFD) is a famous herbal formula commonly prescribed for the treatment of lung-related diseases in the ancient and modern times. Trichosanthis Fructus (TF) and Fritillariae Thunbergii Bulbus (FTB) are
Externí odkaz:
https://doaj.org/article/f461ee3ddee14c349880699c64d84362
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Astragaloside III (AS III), a saponin-like metabolite derived from the traditional Chinese medicine Astragali Radix, has been shown to be effective in the treatment of cancer and heart failure, and a variety of digestive disorders
Externí odkaz:
https://doaj.org/article/76a347154e6a43d8a8d5e637349c2800
Publikováno v:
Journal of Inflammation Research, Vol Volume 16, Pp 6179-6193 (2023)
Yunbo Yan,1 Linqian Yu,1 Binyang Chen,1 Chang’an Cao,1 Hairong Zhao,1,2 Qiang Wang,1 De Xie,1 Yuemei Xi,1 Chenggui Zhang,2 Jidong Cheng1,3 1Department of Internal Medicine, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen Univer
Externí odkaz:
https://doaj.org/article/980649787e6b4b08b5cd8533cf48b060
Publikováno v:
Applied Biological Chemistry, Vol 66, Iss 1, Pp 1-10 (2023)
Abstract Keratinocytes exposed to UVB induce the production of cytokines, which activate fibroblasts and increase the expression of matrix metalloproteinases (MMPs). The increased expression of MMPs leads to connective tissue damage and wrinkle forma
Externí odkaz:
https://doaj.org/article/1f1024e8eca0400f8aa7c580a39eab28