Zobrazeno 1 - 10
of 261
pro vyhledávání: '"MAP4K4"'
Autor:
Yuqiong Chen, Su Li, Bo Guan, Xiaopei Yan, Chao Huang, Yingqiang Du, Fan Yang, Nannan Zhang, Yafei Li, Jian Lu, Jiankang Wang, Jun Zhang, Zhangwei Chen, Chao Chen, Xiangqing Kong
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-18 (2024)
Abstract Dynamin-related protein 1 (Drp1) is a crucial regulator of mitochondrial dynamics, the overactivation of which can lead to cardiovascular disease. Multiple distinct posttranscriptional modifications of Drp1 have been reported, among which S-
Externí odkaz:
https://doaj.org/article/a9a83c519bda4bfda3cd116621c91fd9
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) has recently emerged as a promising therapeutic target in cancer. In this study, we explored the biological function of MAP4K4 in radioresistant breast cancer cells using two M
Externí odkaz:
https://doaj.org/article/1576c2812425494eb616c51d4ceb671b
Autor:
Chao-Di Chang, Min-Wu Chao, Hsueh-Yun Lee, Yi-Ting Liu, Huang-Ju Tu, Ssu-Ting Lien, Tony Eight Lin, Tzu-Ying Sung, Shih-Chung Yen, Sing-Han Huang, Kai-Cheng Hsu, Shiow-Lin Pan
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Inhibiting a specific target in cancer cells and reducing unwanted side effects has become a promising strategy in pancreatic cancer treatment. MAP4K4 is associated with pancreatic cancer development and correlates with poor clinical outcomes. By pho
Externí odkaz:
https://doaj.org/article/eeb87040e05f48b3ad27fb6a79897905
Publikováno v:
Molecular and Cellular Probes, Vol 71, Iss , Pp 101920- (2023)
Background: Aberrant expression of circRNAs is involved in the progression of hepatocellular carcinoma (HCC). This study aimed at screening the pro-tumorigenic circular RNAs (circRNAs) in HCC and the mechanisms of circCPSF6 expression influencing HCC
Externí odkaz:
https://doaj.org/article/640a910d935748598d23ca2725d6ed44
Autor:
Hongxin Huang, Jie Wang
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 34-37 (2022)
Some cervical cancer patients show poor response to neoadjuvant chemotherapy. Although it has been demonstrated that macroautophagy/autophagy contributes to the poor chemosensitivity, the underlying mechanism has not yet been fully clarified. In this
Externí odkaz:
https://doaj.org/article/dfa9dcd6a6bc4b35b0e9d6073deb51c6
Autor:
Fangzhen Luo, Yating Wen, Lanhua Zhao, Shengmei Su, Wenbo Lei, Lili Chen, Chaoqun Chen, Qiulin Huang, Zhongyu Li
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 444-457 (2022)
Persistent infection of Chlamydia trachomatis is thought to be responsible for the debilitating sequelae of blinding trachoma and infertility. Inhibition of host cell apoptosis is a persistent C. trachomatis infection mechanism. ZEB1-AS1 is a long no
Externí odkaz:
https://doaj.org/article/d77a66c69e584e239f2a907ecc0c7bca
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/68a5e76238aa47128bae7c4dcc5c749f
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
MAP4K4 is a serine/threonine kinase that belongs to the MAP kinase family and plays a critical role in embryogenesis and cellular migration. It contains approximately 1,200 amino acids and has a molecular mass of 140 kDa. MAP4K4 is expressed in most
Externí odkaz:
https://doaj.org/article/46933293b6954164ba5313ec91fa4bca
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The finely tuned integration of intra- and extracellular cues by components of the mitogen-activated protein kinase (MAPK) signaling pathways controls the mutually exclusive phenotypic manifestations of uncontrolled growth and tumor cell disseminatio
Externí odkaz:
https://doaj.org/article/6caf5fb8ff754f6985115f4fe4587b28