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Publikováno v:
Middle East Journal of Cancer, Vol 12, Iss 3, Pp 350-356 (2021)
Background: Acute lymphoblastic leukemia (ALL) is known as a sort of malignancy in the blood lymphoid progenitors, specifically in B and T precursors of the lymphocyte. Autophagy is a protected hemostatic and catabolic process during evolution, throu
Externí odkaz:
https://doaj.org/article/96566eb8be0c4429814687cf2279a658
Autor:
Amanda Demeter, Anne-Claire Jacomin, Lejla Gul, Ashleigh Lister, James Lipscombe, Rachele Invernizzi, Priscilla Branchu, Iain Macaulay, Ioannis P. Nezis, Robert A. Kingsley, Tamas Korcsmaros, Isabelle Hautefort
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Macroautophagy is a ubiquitous homeostasis and health-promoting recycling process of eukaryotic cells, targeting misfolded proteins, damaged organelles and intracellular infectious agents. Some intracellular pathogens such as Salmonella enterica sero
Externí odkaz:
https://doaj.org/article/2473b25ba8984379ac6d561d72fc768c
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Background: Stroke is one of the most common deadly diseases with an estimated 780,000 new cases globally, of which ischemic stroke accounts for over 80% of all cases. Ferroptosis is a new form of programmed cell death that plays a vital role in many
Externí odkaz:
https://doaj.org/article/58bf43f7f3874715be538ee9f9578222
Autor:
Stephane Esnault, Paul S. Fichtinger, Karina T. Barretto, Frances J. Fogerty, Ksenija Bernau, Deane F. Mosher, Sameer K. Mathur, Nathan Sandbo, Nizar N. Jarjour
Publikováno v:
Cells, Vol 11, Iss 11, p 1821 (2022)
The presence of eosinophils in the airway is associated with asthma severity and risk of exacerbations. Eosinophils deposit their damaging products in airway tissue, likely by degranulation and cytolysis. We previously showed that priming blood eosin
Externí odkaz:
https://doaj.org/article/242f93c7f71443118998f4a3460d1fd0
Publikováno v:
Indonesian Journal of Tropical and Infectious Disease, Vol 7, Iss 1, Pp 6-10 (2018)
M. tuberculosis (MTB) is an intracelular bacteria that live in the host macrophage cells. Several organs can be affected by tuberculosis but most major illnesses are lung diseases. Immediately after infection, MTB will be phagocytosed by the alveolar
Externí odkaz:
https://doaj.org/article/c26fdc8ac1544a5597de43e6ffd9034d
Autor:
Pei-Feng Liu, Chih-Wen Shu, Hsiu-Chen Yang, Cheng-Hsin Lee, Huei-Han Liou, Luo-Ping Ger, Yen-Dun Tony Tzeng, Wen-Ching Wang
Publikováno v:
Biomedicines, Vol 9, Iss 11, p 1514 (2021)
Breast cancer is the leading cause of cancer death in women worldwide. The microtubule-associated protein light chain 3B (MAP1LC3B) and adaptor sequestosome 1 (SQSTM1) are two major markers for autophagy. Increased protein levels of MAP1LC3B and SQST
Externí odkaz:
https://doaj.org/article/c14a1d12b6d4425d880982a056e78aa1
Publikováno v:
Autophagy
Dysregulated NLRP3 inflammasome activity results in uncontrolled inflammation, which is the basis of many chronic diseases. Although the regulatory mechanism has been gradually clarified after a long period of research, the metabolic regulation of NL
Autor:
Wei-Jye Lin, Wei Wang, Na Li, Diefei Liang, Tingting Zeng, Junxiong Qiu, Chuan Yang, Kan Sun, Xiaoyi Wang, Meng Ren, Lili You, Li Yan
Publikováno v:
Autophagy. 18:1318-1337
Dysregulation of macroautophagy/autophagy contributes to the delay of wound healing in diabetic skin. N6-methyladenosine (m6A) RNA modification is known to play a critical role in regulating autophagy. In this study, it was found that SQSTM1/p62 (seq
Autor:
Jui-Ping Weng, Shu-Chen Wei, Xin-Yu Chang, Liang-Chuan Lai, Po-Yu Lin, Yen-Hsuan Ni, Linda C.H. Yu, Yi-Hsuan Li, Yung-Ming Jeng, Yin-Wen Shue, Jin-Town Wang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 57-79 (2022)
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 57-79 (2022)
Background & Aims Microbiota dysbiosis and mucosa-associated bacteria are involved in colorectal cancer progression. We hypothesize that an interaction between virulent pathobionts and epithelial defense promotes tumorigenesis. Methods Chemical-induc