Zobrazeno 1 - 10
of 21
pro vyhledávání: '"MAMI MUTOH"'
Autor:
Ko Nakanishi, Mami Mutoh, Sachiko Itoh, Sumitaka Kobayashi, Takeshi Yamaguchi, Hiroyoshi Iwata, Naomi Tamura, Momoko Koishi, Machiko Kasai, Emi Kikuchi, Nanae Yasuura, Reiko Kishi, Yoshiaki Sato
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0312516 (2024)
BackgroundVitamin D is an essential nutrient for maintaining blood calcium and phosphorus levels and controlling bone density. Deficiency in it leads to rickets, osteomalacia, osteoporosis, and various other diseases. Recently, it has gained attentio
Externí odkaz:
https://doaj.org/article/6ea964dadd1143dbb64c545157b6e9a2
Autor:
Shunsuke Kimura, Yutaka Nakamura, Nobuhide Kobayashi, Katsuyuki Shiroguchi, Eiryo Kawakami, Mami Mutoh, Hiromi Takahashi-Iwanaga, Takahiro Yamada, Meri Hisamoto, Midori Nakamura, Nobuyuki Udagawa, Shintaro Sato, Tsuneyasu Kaisho, Toshihiko Iwanaga, Koji Hase
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Microfold cells (M cells) sit at the gut epithelial surface to sample antigens and maintain local immune homeostasis. Here the authors show that M cells are feedback-regulated by M cell-originated osteoprotegerin (OPG) to suppress RNAKL-induced M cel
Externí odkaz:
https://doaj.org/article/99645e0b7f85428f9c603bf38fe18aa1
Autor:
Shunsuke Kimura, Mami Mutoh, Meri Hisamoto, Hikaru Saito, Shun Takahashi, Takanori Asakura, Makoto Ishii, Yutaka Nakamura, Junichiro Iida, Koji Hase, Toshihiko Iwanaga
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Microfold (M) cells residing in the follicle-associated epithelium of mucosa-associated lymphoid tissues are specialized for sampling luminal antigens to initiate mucosal immune responses. In the past decade, glycoprotein 2 (GP2) and Tnfaip2 were ide
Externí odkaz:
https://doaj.org/article/943426e8a1d246cbad9358b588128c28
Autor:
Mami Mutoh, Shigeaki Abe, Teruo Kusaka, Mariko Nakamura, Yasuhiro Yoshida, Junichiro Iida, Hiroto Tachikawa
Publikováno v:
Atoms, Vol 4, Iss 1, p 4 (2015)
The ternary interaction system composed of fluorinated ethylene carbonate, denoted by EC(F), lithium ion (Li+) and a model of nano-structured graphene has been investigated by means of the density functional theory (DFT) method. For comparison, fluor
Externí odkaz:
https://doaj.org/article/d2f89154eda349dd91800425db9c8af1
Autor:
MASAKI DONEN, YASUHITO MORITANI, KOSUKE SHIMAZAKI, KAZUHIRO MATSUSHITA, YUKI MIYAKAMI, MAMI MUTOH, YURI TAKAKUSAGI, YOSHIAKI SATO
Publikováno v:
The Japanese Journal of Jaw Deformities. 32:250-261
Autor:
Teruo Kusaka, Valanezhad Alireza, Tomoya Takada, Ikuya Watanabe, Shigeaki Abe, Yosuke Bando, Pipop Saikaew, Ko Nakanishi, Saori Yoshizawa, Yuko Era, Satoshi Inoue, Miho Tamai, Tsukasa Akasaka, Hidetoshi Oguma, Yasuhiro Yoshida, Yoshiaki Sato, Eri Seitoku, Mami Mutoh, Takayuki Kiba, Hidehiko Sano, Mariko Nakamura
Publikováno v:
Journal of Nanoscience and Nanotechnology. 20:2668-2674
In this study, we investigated water-dispersible surface modification for size- and shape-controlled fullerene nanoparticles (C60P) based on a condensation reaction with di-amino alkane. This modification provided for water dispersibility of C60P and
Autor:
Koji Hase, Meri Hisamoto, Shunsuke Kimura, Mami Mutoh, Toshihiko Iwanaga, Nobuyuki Udagawa, Hiromi Takahashi-Iwanaga, Shintaro Sato, Eiryo Kawakami, Takahiro G. Yamada, Yutaka Nakamura, Katsuyuki Shiroguchi, Midori Nakamura, Nobuhide Kobayashi, Tsuneyasu Kaisho
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Microfold cells (M cells) are responsible for antigen uptake to initiate immune responses in the gut-associated lymphoid tissue (GALT). Receptor activator of nuclear factor-κB ligand (RANKL) is essential for M cell differentiation. Follicle-associat
Autor:
Mami Mutoh, Ko Nakanishi, Junichiro Iida, Shigeaki Abe, Yasuhiro Yoshida, Shino Morimoto, Tomohiko Katsurayama, Tsukasa Akasaka, Yasutaka Yawaka, Satoshi Inoue, Nobuki Iwadera
Publikováno v:
Key Engineering Materials. 696:234-237
In this study, we investigated the cytocompatibility of ceramic nanoparticles on different types of cells. All ceramics nanoparticles investigated in this study except Copper oxide (CuO) exhibited good cytocompatibility and cell viability (90% or mor
Autor:
Junichiro Iida, Mami Mutoh, Shunsuke Kimura, Meri Hisamoto, Toshihiko Iwanaga, Hiromi Takahashi-Iwanaga
Publikováno v:
Cell and Tissue Research. 364(1):175-184
Murine nasopharynx-associated lymphoid tissue (NALT), located at the base of the nasal cavity, serves as a major site for the induction of mucosal immune responses against airway antigens. The follicle-associated epithelium (FAE) covering the luminal
Autor:
Shintaro Sato, Shunsuke Kimura, Yuuki Obata, Takashi Kanaya, Mami Mutoh, Hiroshi Ohno, Ryoji Fujiki, Toshihiko Iwanaga, Tomoo Nakagawa, Tsuneyasu Kaisho, Naoya Kato, Nobuhide Kobayashi, Koji Hase, Daisuke Takahashi, Yutaka Nakamura
Publikováno v:
The Journal of Experimental Medicine
Kimura et al. show that Sox8 is specifically expressed in intestinal M cells. Genetic deletion of Sox8 causes the loss of mature M cells and reduction of antigen uptake in Peyer’s patches, resulting in a decreased antigen-specific IgA response duri