Zobrazeno 1 - 10
of 91
pro vyhledávání: '"MALCOLM MACLEOD"'
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Researchers performing high-quality systematic reviews search across multiple databases to identify relevant evidence. However, the same publication is often retrieved from several databases. Identifying and removing such duplicat
Externí odkaz:
https://doaj.org/article/bf092f0d5903498d8838f0bc31d766c3
Autor:
Grant Mair, Philip White, Philip M. Bath, Keith Muir, Chloe Martin, David Dye, Francesca Chappell, Rüdiger vonKummer, Malcolm Macleod, Nikola Sprigg, Joanna M. Wardlaw, for the RITeS Collaboration
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 7, Pp 1072-1082 (2023)
Abstract Objective Software developed using artificial intelligence may automatically identify arterial occlusion and provide collateral vessel scoring on CT angiography (CTA) performed acutely for ischemic stroke. We aimed to assess the diagnostic a
Externí odkaz:
https://doaj.org/article/0ef113e3813d4edba87369cbfe618482
Autor:
Virginia Chiocchia, Edoardo G. Ostinelli, Catherine Harmer, Michael Browning, Toshi A. Furukawa, Tanatswa Chikaura, Spyridon Siafis, Claire Stansfield, Simonne Wright, Lea Milligan, Claire Friedrich, Georgia Salanti, Carmen Moreno, James Thomas, Malcolm Macleod, Soraya Seedat, Andrea Cipriani, Jennifer Potts
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Background: Anhedonia is a key symptom of depression, and it has been suggested as a potential target for future individualised treatments. However, much is unknown about how interventions enhancing dopaminergic pathways may affect anhedonia symptoms
Externí odkaz:
https://doaj.org/article/02c908305cfa477298199afcc0de874e
Autor:
Toshi A Furukawa, Andrea Cipriani, Edoardo Giuseppe Ostinelli, Georgia Salanti, Malcolm Macleod, Emily Sena, James Thomas, Miranda Wolpert, Susan Michie, Jennifer Potts, Matthias Egger, Soraya Seedat, Stefan Leucht, Virginia Chiocchia, Karla Soares-Weiser, Robert McCutcheon, Ayse Kurtulmus, David Gilbert, Sophie Chung, Spyridon Siafis, Carmen Moreno, Lea Milligan, Janna Hastings, Parisa Mansoori, James M Barker, Simonne Wright, Matilda Simpson, Olufisayo Elugbadebo, Thomy Tonia, Rania Elgarf, Ouma Simple, Niall Boyce, Anjuli Sharma, Julian H Elliott
Publikováno v:
BMJ Mental Health, Vol 26, Iss 1 (2023)
In anxiety, depression and psychosis, there has been frustratingly slow progress in developing novel therapies that make a substantial difference in practice, as well as in predicting which treatments will work for whom and in what contexts. To inter
Externí odkaz:
https://doaj.org/article/044de1dd54964197a4947ffbff17d6d6
Publikováno v:
Systematic Reviews, Vol 11, Iss 1, Pp 1-12 (2022)
Abstract Background Natural language processing could assist multiple tasks in systematic reviews to reduce workflow, including the extraction of PICO elements such as study populations, interventions, comparators and outcomes. The PICO framework pro
Externí odkaz:
https://doaj.org/article/aa612ecabcd24937ada46186c9254c94
Improving the reproducibility and integrity of research: what can different stakeholders contribute?
Publikováno v:
BMC Research Notes, Vol 15, Iss 1, Pp 1-5 (2022)
Abstract Increasing awareness of problems with the reproducibility and integrity of research led the UK Parliament Science and Technology Committee to launch, in July 2021, an inquiry into reproducibility and research integrity. We recognise at least
Externí odkaz:
https://doaj.org/article/5921c9ecd8084758b6e09be63be07df8
Autor:
Jeremy Chataway, Tim Soane, Suvankar Pal, Malcolm Macleod, Jing Liao, Fraser S Brown, Charis Wong, Ankur Singh, Gavin Langlands, Elizabeth Elliott, Jenna M Gregory, Siddharthan Chandran, Robert Swingler, Peter Connick, Suzanne Quigley, Peter Foley, Alexandra Thompson, Stella A Glasmacher, D Leighton, Arpan R Mehta, Aimal Ahmad Khan, John Cafferkey, Kieren Egan, Hanna M Vesterinen, Maarij Anwar, Caitlin Beagan, Alessandra Cardinali, Jane Yi Chiam, Claire Chiang, Victoria Collins, Joyce Dormido, Yu Cheng Foo, Lily Fulton-Humble, Angus B Gane, Áine Heffernan, Kiran Jayaprakash, Nimesh Jayasuriya, Amina Kaddouri, Jamie Kiernan, Jiaming Liu, James Lyon, Alyssa Meng, Vivienne Nguyen, Na Hyun Park, Yousuf Rashid, Andrea Salzinger, Bethany Shiell, Olaf Tomala, Fergal M Waldron, Bhuvaneish T Selvaraj
Publikováno v:
BMJ Open, Vol 13, Iss 2 (2023)
Objectives Motor neuron disease (MND) is an incurable progressive neurodegenerative disease with limited treatment options. There is a pressing need for innovation in identifying therapies to take to clinical trial. Here, we detail a systematic and s
Externí odkaz:
https://doaj.org/article/8485ba3c3ebb46a882ab95ef3fcbf8c4
Autor:
Andrew J. Stewart, Emily K. Farran, James A. Grange, Malcolm Macleod, Marcus Munafò, Phil Newton, David R. Shanks, the UKRN Institutional Leads
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-4 (2021)
Abstract The adoption and incentivisation of open and transparent research practices is critical in addressing issues around research reproducibility and research integrity. These practices will require training and funding. Individuals need to be in
Externí odkaz:
https://doaj.org/article/4b59287c070c4bdc9b0f5e49cd4eb75b
Publikováno v:
BMC Research Notes, Vol 15, Iss 1, Pp 1-3 (2022)
Abstract There are many factors that contribute to the reproducibility and replicability of scientific research. There is a need to understand the research ecosystem, and improvements will require combined efforts across all parts of this ecosystem.
Externí odkaz:
https://doaj.org/article/1a8aecd673ab4f6c98fb442e99f82dff
Autor:
Nicola L. Harman, Adrián Sanz-Moreno, Stamatia Papoutsopoulou, Katie A. Lloyd, Kamar E. Ameen-Ali, Malcolm Macleod, Paula R. Williamson
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background In pre-clinical research, systematic reviews have the potential to mitigate translational challenges by facilitating understanding of how pre-clinical studies can inform future clinical research. Yet their conduct is encumbered by
Externí odkaz:
https://doaj.org/article/03af31e45f7c442b85c39c59fae9cfd2