Zobrazeno 1 - 10
of 189
pro vyhledávání: '"MAKOTO MIYAGISHI"'
Autor:
Rendy Hosea, Wei Duan, Ian Timothy Sembiring Meliala, Wenfang Li, Mankun Wei, Sharon Hillary, Hezhao Zhao, Makoto Miyagishi, Shourong Wu, Vivi Kasim
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract Spindle assembly checkpoint (SAC) is a crucial safeguard mechanism of mitosis fidelity that ensures equal division of duplicated chromosomes to the two progeny cells. Impaired SAC can lead to chromosomal instability (CIN), a well‐recognize
Externí odkaz:
https://doaj.org/article/3548cfab493e4f4b866badf338d23056
Autor:
Masahito Kawazu, Kayoko Saso, Kit I Tong, Tracy McQuire, Kouichiro Goto, Dong-Ok Son, Andrew Wakeham, Makoto Miyagishi, Tak W Mak, Hitoshi Okada
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303780 (2024)
[This corrects the article DOI: 10.1371/journal.pone.0017830.].
Externí odkaz:
https://doaj.org/article/e96579d1f54e4604860ca673c545d2d9
Autor:
Yu Tang, Wenfang Li, Li Qiu, Xia Zhang, Lei Zhang, Makoto Miyagishi, Hezhao Zhao, Shourong Wu, Vivi Kasim
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-12 (2023)
Abstract Abnormal glucose metabolism is a highlight of tumor metabolic reprogramming and is closely related to the development of malignancies. p52-ZER6, a C2H2-type zinc finger protein, promotes cell proliferation and tumorigenesis. However, its rol
Externí odkaz:
https://doaj.org/article/e6c75bf9227a47ec8be5a13281dd0b8d
Autor:
Tianwei Huang, Yuya Sato, Akiko Kuramochi, Yoshio Ohba, Masayuki Sano, Makoto Miyagishi, Hiroaki Tateno, Renu Wadhwa, Kazunori Kawasaki, Takeyuki Uchida, Kristina N. Ekdahl, Bo Nilsson, Ung-il Chung, Yuji Teramura
Publikováno v:
Regenerative Therapy, Vol 22, Iss , Pp 90-98 (2023)
Exosomes (diameter 30–200 nm) are a subtype of extracellular vesicles secreted by cells containing DNA, microRNA (miRNA), and proteins. Exosomes are expected to be valuable as a means of delivering drugs or functional miRNAs in treatment of disease
Externí odkaz:
https://doaj.org/article/848925f978da4a4395047b7007ba6239
Autor:
Mankun Wei, Uli Nurjanah, Juan Li, Xinxin Luo, Rendy Hosea, Yanjun Li, Jianting Zeng, Wei Duan, Guanbin Song, Makoto Miyagishi, Vivi Kasim, Shourong Wu
Publikováno v:
Advanced Science, Vol 10, Iss 23, Pp n/a-n/a (2023)
Abstract Cancer stem cells (CSCs) are associated with tumor progression, recurrence, and therapeutic resistance. To maintain their pool while promoting tumorigenesis, CSCs divide asymmetrically, producing a CSC and a highly proliferative, more differ
Externí odkaz:
https://doaj.org/article/9db1593e56744d608075d0d18b108172
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
Inomata et al. isolate zinc-dependent DNAzymes with compact catalytic core sequences displaying highly versatile hydrolysis activity. The cleavable substrate variation for the DNAzymes (ZincDz2 and ZincDz2-v2) is very broad and the authors further de
Externí odkaz:
https://doaj.org/article/667af51242b84672bb30a21379eb5f19
Autor:
Yanjun Li, Juan Li, Zhuolin Li, Mankun Wei, Hezhao Zhao, Makoto Miyagishi, Shourong Wu, Vivi Kasim
Publikováno v:
Advanced Science, Vol 9, Iss 13, Pp n/a-n/a (2022)
Abstract Ferroptosis is a type of programmed cell death caused by disruption of redox homeostasis and is closely linked to amino acid metabolism. Yin Yang 2 (YY2) and its homolog Yin Yang 1 (YY1) are highly homologous, especially in their zinc‐fing
Externí odkaz:
https://doaj.org/article/d7fe6498cd2c4cb9b6de47acdc9f0cf4
Autor:
Can Huang, Shourong Wu, Wenfang Li, Arin Herkilini, Makoto Miyagishi, Hezhao Zhao, Vivi Kasim
Publikováno v:
EBioMedicine, Vol 48, Iss , Pp 248-263 (2019)
Background: Aberrant expression of p53 and its downstream gene p21 is closely related to alterations in cell cycle and cell proliferation, and is common among cancer patients. However, the underlying molecular mechanism has not been fully unravelled.
Externí odkaz:
https://doaj.org/article/60f4ccf0e58c415db2973c1143bbcbf0
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59445 (2013)
RNA interference (RNAi) is an endogenous RNA-destruction phenomenon induced by certain double-stranded RNAs (dsRNAs). In RNAi, dsRNAs are processed into small interfering RNAs (siRNAs) which in turn trigger the cleavage of the target mRNA. Here, usin
Externí odkaz:
https://doaj.org/article/93b925023ff941bf971982c7138ff9ec
Autor:
Masahito Kawazu, Kayoko Saso, Kit I Tong, Tracy McQuire, Kouichiro Goto, Dong-Ok Son, Andrew Wakeham, Makoto Miyagishi, Tak W Mak, Hitoshi Okada
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17830 (2011)
Estrogen is a key regulator of normal function of female reproductive system and plays a pivotal role in the development and progression of breast cancer. Here, we demonstrate that JMJD2B (also known as KDM4B) constitutes a key component of the estro
Externí odkaz:
https://doaj.org/article/53a6bc086de94e419cc4ec772d6d7202