Zobrazeno 1 - 10
of 516
pro vyhledávání: '"MAKOTO ISHIKAWA"'
Autor:
Michiko Ohno-Oishi, Zou Meiai, Kota Sato, Seiya Kanno, Chihiro Kawano, Makoto Ishikawa, Toru Nakazawa
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101723- (2024)
Glaucoma is a common cause of blindness worldwide. Genetic effects are believed to contribute to the onset and progress of glaucoma, but the underlying pathological mechanisms are not fully understood. Here, we set out to introduce mutations into the
Externí odkaz:
https://doaj.org/article/1f568c414c6f44db9d7179479e0be3c4
Autor:
Makoto Ishikawa, Yukitoshi Izumi, Kota Sato, Taimu Sato, Charles F. Zorumski, Hiroshi Kunikata, Toru Nakazawa
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
Externí odkaz:
https://doaj.org/article/b2a5fdc11ee349ff9614d25fe0a81372
Autor:
Yukitoshi Izumi, Makoto Ishikawa, Toru Nakazawa, Hiroshi Kunikata, Kota Sato, Douglas F Covey, Charles F Zorumski
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 5, Pp 1004-1008 (2023)
Neurosteroids are rapidly emerging as important new therapies in neuropsychiatry, with one such agent, brexanolone, already approved for treatment of postpartum depression, and others on the horizon. These steroids have unique properties, including n
Externí odkaz:
https://doaj.org/article/ad9749e901f447faa79b435493d888aa
Publikováno v:
International Journal of Implant Dentistry, Vol 8, Iss 1, Pp 1-9 (2022)
Abstract Background Implant-supported removable partial dentures (ISRPDs) provide effective prosthodontic treatment for partially edentulous patients. ISRPDs offer greater patient satisfaction and better oral function compared with removable partial
Externí odkaz:
https://doaj.org/article/df0decfaed7e4df5ae4529880c9337ba
Autor:
Makoto Ishikawa, Yukitoshi Izumi, Kota Sato, Taimu Sato, Charles F. Zorumski, Hiroshi Kunikata, Toru Nakazawa
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
Glaucoma is a multifactorial neurodegenerative disease characterized by a progressive optic neuropathy resulting in visual field defects. Elevated intraocular pressure (IOP) is the greatest risk factor for the development of glaucoma, and IOP reducti
Externí odkaz:
https://doaj.org/article/b9bb0c7e774a47388fee5f397f4ce194
Autor:
Makoto Ishikawa, Toru Nakazawa, Hiroshi Kunikata, Kota Sato, Takeshi Yoshitomi, Kathiresan Krishnan, Douglas F. Covey, Charles F. Zorumski, Yukitoshi Izumi
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
In an ex vivo rat ocular hypertension (OHT) model, the neurosteroid allopregnanolone (AlloP) exerts neuroprotective effects via enhancement of both GABAA receptors and autophagy. We now examine whether its enantiomer (ent-AlloP), which is largely ina
Externí odkaz:
https://doaj.org/article/8debbb05cfa341cf9e039f7b3d81b327
Autor:
Noriyuki Doukyu, Makoto Ishikawa
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0241126 (2020)
Two genes (choRI and choRII) encoding cholesterol oxidases belonging to the vanillyl-alcohol oxidase (VAO) family were cloned on the basis of putative cholesterol oxidase gene sequences in the genome sequence data of Rhodococcus erythropolis PR4. The
Externí odkaz:
https://doaj.org/article/40e00b2a34e2457fba6e0875a17f2ca3
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170733 (2017)
The influence of myopia on glaucoma progression remains unknown, possibly because of the multifactorial nature of glaucoma and difficulty in assessing a solo contribution of myopia. The purpose of this study is to investigate the association of myopi
Externí odkaz:
https://doaj.org/article/0ec85d59c05a4354992b06c013bf6ff8
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161961 (2016)
To examine the association of myopia with the visual field (VF) defects in open-angle glaucoma (OAG) using paired eyes to eliminate the effect of unknown confounding factors that are diverse among individuals.One hundred eighteen eyes of 59 subjects
Externí odkaz:
https://doaj.org/article/becd1defc70a43cf925ef383e7c5895b
Publikováno v:
Sensors, Vol 12, Iss 3, Pp 3200-3203 (2012)
We have constructed an experimental system to measure a piconewton lateral force using dual cantilevers which cross with each other. The resolution of the lateral force is estimated to be 3.3 p ± 0.2 pN, which is comparable to forces due to thermal
Externí odkaz:
https://doaj.org/article/b75a2e65b98a4a69a4a6b591090e773a