Zobrazeno 1 - 10
of 308
pro vyhledávání: '"MAJOR OUTER-MEMBRANE"'
Autor:
Mariam Mohagheghi, Abisola Abisoye-Ogunniyan, Angela C. Evans, Alexander E. Peterson, Gregory A. Bude, Steven Hoang-Phou, Byron Dillon Vannest, Dominique Hall, Amy Rasley, Dina R. Weilhammer, Nicholas O. Fischer, Wei He, Beverly V. Robinson, Sukumar Pal, Anatoli Slepenkin, Luis de la Maza, Matthew A. Coleman
Publikováno v:
Vaccines, Vol 12, Iss 11, p 1246 (2024)
Background: Vaccine development against Chlamydia, a prevalent sexually transmitted infection (STI), is imperative due to its global public health impact. However, significant challenges arise in the production of effective subunit vaccines based on
Externí odkaz:
https://doaj.org/article/8a73fe6443b6407f917f96d9f4d91582
Autor:
Ida Rosenkrands, Anja W. Olsen, Sara Knudsen, Nida Dehari, Helene Bæk Juel, Hannah M. Cheeseman, Peter Andersen, Robin J. Shattock, Frank Follmann
Publikováno v:
EBioMedicine, Vol 104, Iss , Pp 105140- (2024)
Summary: Background: Chlamydia trachomatis (CT) Major Outer Membrane Protein (MOMP) holds a neutralising epitope in the Variable Domain 4 (VD4), and this region’s immune dominance during infection is well known. This study aimed to assess the antib
Externí odkaz:
https://doaj.org/article/56f3ce12fe2f407d8fceb4d157c98d9d
Akademický článek
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Autor:
Arif Eman Dhahir, Saeed Nahla Mohammad, Rachid Shwan Kamal, Dyary Hiewa Othman, Rashid Peshnyar M.A.
Publikováno v:
Polish Journal of Microbiology, Vol 71, Iss 1, Pp 115-121 (2022)
In this manuscript, we report the proteins macrophage infectivity potentiator (mip, CAB080), major outer membrane protein (momp, CAB048), and polymorphic outer membrane protein (pmp18D, CAB776) that are expressed in different times of pregnancy in mi
Externí odkaz:
https://doaj.org/article/9e456e64327d4a2a9977aaf86e9a5187
Autor:
Jennifer C. Okoye, Alexandria Holland, Matthaios Pitoulias, Vasileios Paschalis, Artem Piddubnyi, Osman A. Dufailu, Thomas Borén, Neil J. Oldfield, Jafar Mahdavi, Panos Soultanas
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Campylobacter jejuni colonizes hosts by interacting with Blood Group Antigens (BgAgs) on the surface of gastrointestinal epithelia. Genetic variations in BgAg expression affects host susceptibility to C. jejuni. Here, we show that the essential major
Externí odkaz:
https://doaj.org/article/c84216198c4f45a196212118ed939b0b
Autor:
Sukumar Pal, Anatoli Slepenkin, Jiin Felgner, D. Huw Davies, Philip Felgner, Luis M. de la Maza
Publikováno v:
Pathogens, Vol 12, Iss 7, p 863 (2023)
There is an urgent need to produce a vaccine for Chlamydia trachomatis infections. Here, using the Chlamydia muridarum major outer membrane protein (MOMP) as an antigen, four adjuvant combinations IVAX-1 (MPLA+CpG-1018+AddaVax), IVAX-2 (MPLA+CpG-1018
Externí odkaz:
https://doaj.org/article/ce04732fcc6c4827b8a041065e118dca
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/34fd014e7e064972b5c64939b75c0411
Autor:
Sukumar Pal, Salvador Fernando Ausar, Delia F. Tifrea, Chunmei Cheng, Scott Gallichan, Violette Sanchez, Luis M. de la Maza, Lucian Visan
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 10, Pp 2537-2547 (2020)
Chlamydia trachomatis is the most common bacterial sexually-transmitted pathogen for which there is no vaccine. We previously demonstrated that the degree of phosphate substitution in an aluminum hydroxide adjuvant in a TLR-4-based C. trachomatis ser
Externí odkaz:
https://doaj.org/article/7997cd92ed784973b63e423efe2f1eef
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Chlamydia psittaci (C. psittaci) is a crucial zoonotic pathogen that causes severe respiratory and reproductive system disease in humans and animals. In our pioneer study, polymorphic membrane protein G (PmpG) mediated attachment to host cells as the
Externí odkaz:
https://doaj.org/article/6494ab41c04248929994b2d100067c58
Autor:
Anatoli Slepenkin, Sukumar Pal, Steven Hoang-Phou, Abisola Abisoye-Ogunniyan, Amy Rasley, Patrik D’haeseleer, Matthew A. Coleman, Luis M. de la Maza
Publikováno v:
Vaccines, Vol 11, Iss 3, p 504 (2023)
Chlamydia trachomatis is the most common bacterial sexually transmitted pathogen. The number of chlamydial infections continuous to increase and there is an urgent need for a safe and efficacious vaccine. To assess the ability of the Chlamydia murida
Externí odkaz:
https://doaj.org/article/4728940a3558479db0f4033a49f92670