Zobrazeno 1 - 10
of 249
pro vyhledávání: '"MAIT cell"'
Autor:
Patrik Sundström, Nikita Dutta, William Rodin, Andreas Hallqvist, Sukanya Raghavan, Marianne Quiding Järbrink
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Mucosal-associated invariant T (MAIT) cells constitute one of the most numerous unconventional T cell subsets, and are characterized by rapid release of Th1- and Th17-associated cytokines and increased cytotoxic functions following activation. MAIT c
Externí odkaz:
https://doaj.org/article/82e5d77d60e74f5fbca2d4e7be410777
Autor:
Jiayu Ding, Yanmei Li, Zhiqin Wang, Feng Han, Ming Chen, Jun Du, Tong Yang, Mei Zhang, Yingai Wang, Jing Xu, Gaoya Wang, Yong Xu, Xiuhua Wu, Jian Hao, Xinlei Liu, Guangxin Zhang, Na Zhang, Wenwen Sun, Zhigang Cai, Wei Wei
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectivesThe objective of this study was to profile the transcriptional profiles of peripheral blood mononuclear cells (PBMCs) and their immune repertoires affected by anti-synthetase syndrome (ASS) at the single-cell level.MethodsWe performed singl
Externí odkaz:
https://doaj.org/article/4cd00be4f4ed436db6f6f96532b8d64a
Autor:
Emi Ito, Sho Yamasaki
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Mucosal-associated invariant T (MAIT) cells are a major subset of innate-like T cells that function at the interface between innate and acquired immunity. MAIT cells recognize vitamin B2-related metabolites produced by microbes, through semi-invarian
Externí odkaz:
https://doaj.org/article/36d232c4016f4adcb285cb1e29fc6fde
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Mucosal-associated invariant T (MAIT) cells play diverse roles in cancer, infectious diseases, and immunotherapy. This review explores their intricate involvement in cancer, from early detection to their dual functions in promoting inflammation and m
Externí odkaz:
https://doaj.org/article/96e520efc1a34d76ba479040ea969b24
Autor:
Elena Litvinova, Carine Bounaix, Guillaume Hanouna, Jennifer Da Silva, Laura Noailles, Lucie Beaudoin, Michael Padden, Nessrine Bellamri, Agnès Lehuen, Eric Daugas, Renato C. Monteiro, Héloïse Flament
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSystemic lupus erythematosus (SLE) is an autoimmune disease in which circulating immune complexes can cause different types of glomerulonephritis, according to immune deposits and to the type of glomerular cell injury. Proliferative lesio
Externí odkaz:
https://doaj.org/article/78d377201d44498b87229e679bc608e5
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The interaction between peripheral immune cells and the brain is an important component of the neuroimmune axis. Unconventional T cells, which include natural killer T (NKT) cells, mucosal-associated invariant T (MAIT) cells, γδ T cells, and other
Externí odkaz:
https://doaj.org/article/8b612222550e4f06bee7ce18b2fdbead
Autor:
Adam G. Nelson, Huimeng Wang, Phoebe M. Dewar, Eleanor M. Eddy, Songyi Li, Xin Yi Lim, Timothy Patton, Yuchen Zhou, Troi J. Pediongco, Lucy J. Meehan, Bronwyn S. Meehan, Jeffrey Y. W. Mak, David P. Fairlie, Andrew W. Stent, Lars Kjer-Nielsen, James McCluskey, Sidonia B. G. Eckle, Alexandra J. Corbett, Michael N. T. Souter, Zhenjun Chen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMucosal-associated invariant T (MAIT) cells are a population of innate-like T cells, which mediate host immunity to microbial infection by recognizing metabolite antigens derived from microbial riboflavin synthesis presented by the MHC-I-
Externí odkaz:
https://doaj.org/article/ac4779a9843b421f9ed2624be5af4d23
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe primary strategy for reducing the incidence of COVID-19 is SARS-CoV-2 vaccination. Few studies have explored T cell subset differentiation and gene expressions induced by SARS-CoV-2 vaccines. Our study aimed to analyze T cell dynamics a
Externí odkaz:
https://doaj.org/article/0d83042e9bf34cde83e8408a6302f36a
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
MAIT cells are multifunctional innate-like effector cells recognizing bacterial-derived vitamin B metabolites presented by the non-polymorphic MHC class I related protein 1 (MR1). However, our understanding of MR1-mediated responses of MAIT cells upo
Externí odkaz:
https://doaj.org/article/2ad405d16cf840c0a1e5ef2e5f3cebd2
Autor:
Zhao Wang, Sudong Zhang, Xiaoyu Zhang, Li Liu, Lukun Zhou, Yuyan Shen, Rongli Zhang, Yi He, Donglin Yang, Erlie Jiang, Xiaoming Feng, Jiaxi Zhou, Tao Cheng, Mingzhe Han, Sizhou Feng
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-16 (2022)
Abstract Background Mucosal-associated invariant T (MAIT) cells are innate-like T cells, some studies have reported that the number of circulating MAIT cells reduced in patients with acute graft-versus-host-disease (aGVHD) development. However, the r
Externí odkaz:
https://doaj.org/article/aa0b46951ac746a5b69c8af3cdf278ba