Zobrazeno 1 - 10
of 82
pro vyhledávání: '"MAIK BRUNE"'
Effects of Oxiris® Therapy on Cytokine Elimination after a LPS Infusion—An Experimental Animal Study
Autor:
Armin Kalenka, Philipp Arens, Ralf M. Müllenbach, Markus A. Weigand, Maik Brune, Mascha O. Fiedler-Kalenka
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9283 (2024)
The clinical effectiveness of Oxiris®, particularly in reducing cytokines, remains uncertain due to the limited data provided. This study explored and analyzed the application value of Oxiris® endotoxin adsorption technology in a large animal model
Externí odkaz:
https://doaj.org/article/9e773229d431428e9ce12f9c0eab4016
Autor:
Simon Renders, Arthur Flohr Svendsen, Jasper Panten, Nicolas Rama, Maria Maryanovich, Pia Sommerkamp, Luisa Ladel, Anna Rita Redavid, Benjamin Gibert, Seka Lazare, Benjamin Ducarouge, Katharina Schönberger, Andreas Narr, Manon Tourbez, Bertien Dethmers-Ausema, Erik Zwart, Agnes Hotz-Wagenblatt, Dachuan Zhang, Claudia Korn, Petra Zeisberger, Adriana Przybylla, Markus Sohn, Simon Mendez-Ferrer, Mathias Heikenwälder, Maik Brune, Daniel Klimmeck, Leonid Bystrykh, Paul S. Frenette, Patrick Mehlen, Gerald de Haan, Nina Cabezas-Wallscheid, Andreas Trumpp
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Haematopoietic stem cells (HSCs) are characterized by their self-renewal potential and associated dormancy. Here the authors show that niche produced netrin-1 preserves HSC quiescence and self-renewal via neogenin-1, and that decline of netrin-1 prod
Externí odkaz:
https://doaj.org/article/3c2f87ae1c244f13b1b1ad0a9daad872
Autor:
Susanne Gaul, Khurrum Shahzad, Rebekka Medert, Ihsan Gadi, Christina Mäder, Dagmar Schumacher, Angela Wirth, Saira Ambreen, Sameen Fatima, Jes-Niels Boeckel, Hamzah Khawaja, Jan Haas, Maik Brune, Peter P. Nawroth, Berend Isermann, Ulrich Laufs, Marc Freichel
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ObjectiveAtherosclerosis, the main pathology underlying cardiovascular diseases is accelerated in diabetic patients. Genetic mouse models require breeding efforts which are time-consuming and costly. Our aim was to establish a new nongenetic model of
Externí odkaz:
https://doaj.org/article/56c5ef21b0ed4df3b798f8eedcf9f944
Autor:
Sevil Korkmaz-Icöz, Gianluca Sistori, Sivakkanan Loganathan, Alex Ali Sayour, Paige Brlecic, Tamás Radovits, Maik Brune, Matthias Karck, Gábor Szabó
Publikováno v:
Stem Cells International, Vol 2022 (2022)
Ischemia/reperfusion injury (IRI) remains a challenge in coronary artery bypass grafting (CABG). Diabetic patients with coronary artery disease are more likely to require CABG and therefore run a high risk for cardiovascular complications. Conditione
Externí odkaz:
https://doaj.org/article/7a1a92956b7443d09bb0ecf4e05254f9
Autor:
Jan Simon Scharrenberg, Ayla Yagdiran, Julia Brinkmann, Maik Brune, Jan Siewe, Norma Jung, Esther Mahabir
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 14, Iss 1, Pp 1-13 (2019)
Abstract Background There is still a challenge in discriminating between vertebral osteomyelitis and degenerative diseases of the spine. To this end, we determined the suitability of soluble urokinase-type plasminogen activator receptor (suPAR) and c
Externí odkaz:
https://doaj.org/article/1a75519498674fed91065ca6649a6163
Autor:
Alex Ali Sayour, Sevil Korkmaz-Icöz, Sivakkanan Loganathan, Mihály Ruppert, Viktor Nabil Sayour, Attila Oláh, Kálmán Benke, Maik Brune, Rita Benkő, Eszter Mária Horváth, Matthias Karck, Béla Merkely, Tamás Radovits, Gábor Szabó
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-14 (2019)
Abstract Background The sodium–glucose cotransporter-2 (SGLT2) inhibitor canagliflozin has been shown to reduce major cardiovascular events in type 2 diabetic patients, with a pronounced decrease in hospitalization for heart failure (HF) especially
Externí odkaz:
https://doaj.org/article/2b4ff6d74fa7446eb9caa1ad0e78ee3f
Autor:
Sana S Hasan, Markus Jabs, Jacqueline Taylor, Lena Wiedmann, Thomas Leibing, Viola Nordström, Giuseppina Federico, Leticia P Roma, Christopher Carlein, Gretchen Wolff, Bilgen Ekim‐Üstünel, Maik Brune, Iris Moll, Fabian Tetzlaff, Hermann‐Josef Gröne, Thomas Fleming, Cyrill Géraud, Stephan Herzig, Peter P Nawroth, Andreas Fischer
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 4, Pp n/a-n/a (2020)
Abstract The role of the endothelium is not just limited to acting as an inert barrier for facilitating blood transport. Endothelial cells (ECs), through expression of a repertoire of angiocrine molecules, regulate metabolic demands in an organ‐spe
Externí odkaz:
https://doaj.org/article/1ed45c1818f945c4851ba741b9225b1a
Autor:
Mascha O Fiedler, B Luise Deutsch, Emilis Simeliunas, Dovile Diktanaite, Alexander Harms, Maik Brune, Florian Uhle, Markus Weigand, Thorsten Brenner, Armin Kalenka
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0230830 (2020)
INTRODUCTION:Intra-abdominal hypertension (IAH) is a well-known phenomenon in critically ill patients. Effects of a moderately elevated intra-abdominal pressure (IAP) on lung mechanics are still not fully analyzed. Moreover, the optimal positive end-
Externí odkaz:
https://doaj.org/article/bc5065621b5947db9210aeede873c4c2
Autor:
Katharina Niopek, Bilgen Ekim Üstünel, Susanne Seitz, Minako Sakurai, Annika Zota, Frits Mattijssen, Xiaoyue Wang, Tjeerd Sijmonsma, Yvonne Feuchter, Anna M. Gail, Barbara Leuchs, Dominik Niopek, Oskar Staufer, Maik Brune, Carsten Sticht, Norbert Gretz, Karin Müller-Decker, Hans-Peter Hammes, Peter Nawroth, Thomas Fleming, Michael D. Conkright, Matthias Blüher, Anja Zeigerer, Stephan Herzig, Mauricio Berriel Diaz
Publikováno v:
Cell Reports, Vol 20, Iss 6, Pp 1422-1434 (2017)
Increased pro-inflammatory signaling is a hallmark of metabolic dysfunction in obesity and diabetes. Although both inflammatory and energy substrate handling processes represent critical layers of metabolic control, their molecular integration sites
Externí odkaz:
https://doaj.org/article/2202dbc7845d40ae91de1eae8c20361a
Autor:
Laura Giessing, Marie Ottilie Frenkel, Christoph Zinner, Jan Rummel, Arne Nieuwenhuys, Christian Kasperk, Maik Brune, Florian Azad Engel, Henning Plessner
Publikováno v:
Frontiers in Psychology, Vol 10 (2019)
Police officers are often required to perform under high-stress circumstances, in which optimal task performance is crucial for their and the bystanders’ physical integrity. However, stress responses, particularly anxiety and increased cortisol lev
Externí odkaz:
https://doaj.org/article/eb50344b046940ed819daf34ec9aa3a6