Zobrazeno 1 - 10
of 342
pro vyhledávání: '"MAI SHI"'
Autor:
Ke Wang, Mai Shi, Andrea O. Y. Luk, Alice P. S. Kong, Ronald C. W. Ma, Changhong Li, Li Chen, Elaine Chow, Juliana C. N. Chan
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background Glucokinase (GK) plays a key role in glucose metabolism. In the liver, GK is regulated by GK regulatory protein (GKRP) with nuclear sequestration at low plasma glucose level. Some GK activators (GKAs) disrupt GK-GKRP interaction w
Externí odkaz:
https://doaj.org/article/ab74b99469fc4c329a175d4f6db6e49d
Autor:
Xinge Zhang, Hongjiang Wu, Eric SH Lau, Baoqi Fan, Kit Ying Tsoi, Claudia HT Tam, Aimin Yang, Mai Shi, Elaine Chow, Alice PS Kong, Juliana CN Chan, Wing Hung Tam, Andrea OY Luk, Ronald CW Ma
Publikováno v:
Journal of Diabetes Investigation, Vol 15, Iss 6, Pp 772-781 (2024)
ABSTRACT Aims/Introduction To determine the population health burden attributable to the development of diabetes among women with a history of gestational diabetes mellitus (GDM). Materials and Methods We conducted a retrospective analysis of women w
Externí odkaz:
https://doaj.org/article/f70afa538080487d9ce21fb4fab7238b
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Tuberculosis (TB) represents a major global health challenge. Drug resistance in Mycobacterium tuberculosis (MTB) poses a substantial obstacle to effective TB treatment. Identifying genomic mutations in MTB isolates holds promise
Externí odkaz:
https://doaj.org/article/e754e48d1ad648b1b97f43a78c290f16
Autor:
Aimin Yang, Mai Shi, Hongjiang Wu, Eric SH. Lau, Johnny TK. Cheung, Xinge Zhang, Baoqi Fan, Tingting Chen, Alice PS. Kong, Andrea OY. Luk, Ronald CW. Ma, Juliana CN. Chan, Elaine Chow
Publikováno v:
EClinicalMedicine, Vol 71, Iss , Pp 102568- (2024)
Summary: Background: Current labelling advises discontinuation of metformin when estimated glomerular filtration rate (eGFR) 5.0 mmol/L with a concomitant blood pH
Externí odkaz:
https://doaj.org/article/486a5f2183cd43c580f41a3e2ed1fff1
Autor:
Mai Shi, Aimin Yang, Eric S H Lau, Andrea O Y Luk, Ronald C W Ma, Alice P S Kong, Raymond S M Wong, Jones C M Chan, Juliana C N Chan, Elaine Chow
Publikováno v:
PLoS Medicine, Vol 21, Iss 4, p e1004369 (2024)
BackgroundOlder adults with diabetes are at high risk of severe hypoglycemia (SH). Many machine-learning (ML) models predict short-term hypoglycemia are not specific for older adults and show poor precision-recall. We aimed to develop a multidimensio
Externí odkaz:
https://doaj.org/article/2cc1b2e4f382441f9d1fce2c533d5ec8
Autor:
Kelly Yichen Li, Claudia Ha Ting Tam, Hongbo Liu, Samantha Day, Cadmon King Poo Lim, Wing Yee So, Chuiguo Huang, Guozhi Jiang, Mai Shi, Heung Man Lee, TRANSCEND Consortium, Hui-yao Lan, Cheuk-Chun Szeto, Robert L. Hanson, Robert G. Nelson, Katalin Susztak, Juliana C. N. Chan, Kevin Y. Yip, Ronald C. W. Ma
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Epigenetic markers are potential biomarkers for diabetes and related complications. Using a prospective cohort from the Hong Kong Diabetes Register, we perform two independent epigenome-wide association studies to identify methylation marker
Externí odkaz:
https://doaj.org/article/6fafc569b3d44fc4acef9a1d7bbfdf99
Autor:
Chenguang Zhang, Xiaoya Zheng, Zhanjiang Tie, Hui Xi, Mai Shi, Yanjun Ma, Wenbin Chen, Yingjie Mi, Rui Yang, Sifeng Zhao, Xuekun Zhang
Publikováno v:
Viruses, Vol 16, Iss 3, p 355 (2024)
As a common disease, canker seriously affects the yield and quality of fragrant pear due to the lack of effective control measures. Some fungi have been reported to harbor rich reservoirs of viral resources, and some mycoviruses can be used as biocon
Externí odkaz:
https://doaj.org/article/0f7c36b7baae4f6b8c5c6c3ddb5e1a7f
Autor:
Ke Wang, Mai Shi, Chuiguo Huang, Baoqi Fan, Andrea O. Y. Luk, Alice P. S. Kong, Ronald C. W. Ma, Juliana C. N. Chan, Elaine Chow
Publikováno v:
Cardiovascular Diabetology, Vol 21, Iss 1, Pp 1-10 (2022)
Abstract Background Glucokinase activators (GKAs) are an emerging class of glucose lowering drugs that activate the glucose-sensing enzyme glucokinase (GK). Pending formal cardiovascular outcome trials, we applied two-sample Mendelian randomisation (
Externí odkaz:
https://doaj.org/article/693ad199c83d4c29af9f951a9c3f7904
Autor:
Dandan Mao, Eric S.H. Lau, Hongjiang Wu, Aimin Yang, Baoqi Fan, Mai Shi, Claudia H.T. Tam, Elaine Chow, Alice P.S. Kong, Ronald C.W. Ma, Andrea Luk, Juliana C.N. Chan
Publikováno v:
Hepatology Communications, Vol 6, Iss 6, Pp 1350-1360 (2022)
Liver is a major site for glucose metabolism. Patients with type 2 diabetes (T2D) and obesity have increased risk of liver cancer. We explored the association of glycemic burden (GB) and obesity with liver cancer in T2D in the prospective Hong Kong D
Externí odkaz:
https://doaj.org/article/906d1d7e0316437ca15a9ccbcf0a612a
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Observational studies revealed altered gut microbial composition in patients with allergic diseases, which illustrated a strong association between the gut microbiome and the risk of allergies. However, whether such associations reflect causality rem
Externí odkaz:
https://doaj.org/article/bde01f20297844df8131b72e4c6f66d6