Zobrazeno 1 - 10
of 82
pro vyhledávání: '"MAGI1"'
Publikováno v:
Thrombosis Journal, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Tissue factor (TF) activity is stringently regulated through processes termed encryption. Post-translational modification of TF and its interactions with various protein and lipid moieties allows for a multi-step de-encryption of
Externí odkaz:
https://doaj.org/article/15ca8484b98a4059bd680b8ce97d9540
Autor:
Yin Wang, Jun-ichi Abe, Khanh M. Chau, Yongxing Wang, Hang Thi Vu, Loka Reddy Velatooru, Fahad Gulraiz, Masaki Imanishi, Venkata S. K. Samanthapudi, Minh T. H. Nguyen, Kyung Ae Ko, Ling-Ling Lee, Tamlyn N. Thomas, Elizabeth A. Olmsted-Davis, Sivareddy Kotla, Keigi Fujiwara, John P. Cooke, Di Zhao, Scott E. Evans, Nhat-Tu Le
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
We have shown that membrane-associated guanylate kinase with inverted domain structure-1 (MAGI1), a scaffold protein with six PSD95/DiscLarge/ZO-1 (PDZ) domains, is involved in the regulation of endothelial cell (EC) activation and atherogenesis in m
Externí odkaz:
https://doaj.org/article/ff9175760c8b4d4ca6154d8ed9b75802
Autor:
Janine Wörthmüller, Simona Disler, Sylvain Pradervand, François Richard, Lisa Haerri, Gustavo A. Ruiz Buendía, Nadine Fournier, Christine Desmedt, Curzio Rüegg
Publikováno v:
Cells, Vol 12, Iss 15, p 1929 (2023)
MAGI1 acts as a tumor suppressor in estrogen receptor-positive (ER+) breast cancer (BC), and its loss correlates with a more aggressive phenotype. To identify the pathways and events affected by MAGI1 loss, we deleted the MAGI1 gene in the ER+ MCF7 B
Externí odkaz:
https://doaj.org/article/c0dd5c8d85c24b8aa4619c329b4d0ec7
Autor:
Rei J. Abe, Hannah Savage, Masaki Imanishi, Priyanka Banerjee, Sivareddy Kotla, Jesus Paez-Mayorga, Jack Taunton, Keigi Fujiwara, Jong Hak Won, Syed Wamique Yusuf, Nicolas L. Palaskas, Jose Banchs, Steven H. Lin, Keri L. Schadler, Jun-ichi Abe, Nhat-Tu Le
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/139b73ccb4124aedb2f8d5f98e6932af
Akademický článek
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Autor:
Rei J. Abe, Hannah Savage, Masaki Imanishi, Priyanka Banerjee, Sivareddy Kotla, Jesus Paez-Mayorga, Jack Taunton, Keigi Fujiwara, Jong Hak Won, Syed Wamique Yusuf, Nicolas L. Palaskas, Jose Banchs, Steven H. Lin, Keri L. Schadler, Jun-ichi Abe, Nhat-Tu Le
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Previously, we reported that post-translational modifications (PTMs) of MAGI1, including S741 phosphorylation and K931 de-SUMOylation, both of which are regulated by p90RSK activation, lead to endothelial cell (EC) activation. However, roles for p90R
Externí odkaz:
https://doaj.org/article/836e3436f1a44d3aaa7ce3caa0c1d077
Akademický článek
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Autor:
Kedar Ghimire, Jelena Zaric, Begoña Alday-Parejo, Jochen Seebach, Mélanie Bousquenaud, Jimmy Stalin, Grégory Bieler, Hans-Joachim Schnittler, Curzio Rüegg
Publikováno v:
Cells, Vol 8, Iss 5, p 388 (2019)
Fluid shear stress stimulates endothelial nitric oxide synthase (eNOS) activation and nitric oxide (NO) production through multiple kinases, including protein kinase A (PKA), AMP-activated protein kinase (AMPK), AKT and Ca2+/calmodulin-dependent prot
Externí odkaz:
https://doaj.org/article/cbe3fe3214924bfba1ef48d2265393c5
Autor:
Eric Chastre, Larissa Kotelevets
Publikováno v:
Cancers
Cancers, 2021, 13 (17), pp.4264. ⟨10.3390/cancers13174264⟩
Cancers, MDPI, 2021, 13 (17), pp.4264. ⟨10.3390/cancers13174264⟩
Cancers, Vol 13, Iss 4264, p 4264 (2021)
Cancers, 2021, 13 (17), pp.4264. ⟨10.3390/cancers13174264⟩
Cancers, MDPI, 2021, 13 (17), pp.4264. ⟨10.3390/cancers13174264⟩
Cancers, Vol 13, Iss 4264, p 4264 (2021)
Simple Summary MAGI1, 2, and 3 belong to a subgroup of the MAGUK family of scaffolding proteins, and are comprised of 6 PDZ domains, 2 WW domains, and 1 GUK domain. MAGIs associate with cell surface receptors, junctional complexes, and interact selec
Akademický článek
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