Developmental Renal Glomerular Defects at the Origin of Glomerulocystic Disease

Autor: Arianna, Fiorentino, Armelle, Christophorou, Filippo, Massa, Serge, Garbay, Magali, Chiral, Mette, Ramsing, Maria, Rasmussen, Marie-Claire, Gubler, Bettina, Bessieres, Laurence, Heidet, Evelyne, Fischer, Marco, Pontoglio

Publikováno v: Fiorentino, A, Christophorou, A, Massa, F, Garbay, S, Chiral, M, Ramsing, M, Rasmussen, M, Gubler, M-C, Bessieres, B, Heidet, L, Fischer, E & Pontoglio, M 2020, ' Developmental Renal Glomerular Defects at the Origin of Glomerulocystic Disease ', Cell Reports, vol. 33, no. 4, 108304 . https://doi.org/10.1016/j.celrep.2020.108304
Cell Reports
Cell Reports, Elsevier Inc, 2020, 33 (4), pp.108304. ⟨10.1016/j.celrep.2020.108304⟩
Cell Reports, 2020, 33 (4), pp.108304. ⟨10.1016/j.celrep.2020.108304⟩

International audience; The architecture of renal glomeruli is acquired through intricate and still poorly understood developmental steps. In our study we identify a crucial glomerular morphogenetic event in nephrogenesis that drives the remodeling/s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7267091dcb606498e51f563aadcceec7
https://findresearcher.sdu.dk:8443/ws/files/175869624/PIIS2211124720312936.pdf

1900-P: HNF1A Deficiency Leads to Perturbed Glucagon Secretion in Humans

Autor: Magali Chiral, Caroline Bonner, Ioannis Spiliotis, Marco Pontoglio, C. Saponaro, Jochen H. M. Prehn, Julien Thevenet, Gianni Pasquetti, Lia Anguelova, Anthony Piron, Katharine R. Owen, Miriam Cnop, Valery Gmyr, Julie Kerr-Conte, Ana Acosta-Montalvo, François Pattou

Publikováno v: Diabetes. 69

Mutations in HNF1A cause Maturity Onset Diabetes of the Young (HNF1A-MODY). Carriers are normoglycemic in childhood, but with age, they develop hyperglycemia associated with insulin secretory defects and beta cell dysfunction. Although endogenous glu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f5e2c4d893d1bb85a02d0480ccf52b6c
https://doi.org/10.2337/db20-1900-p

A suppressor locus for MODY3-diabetes

Autor: Géraldine Prévost, Munevver Parla Makinistoglu, Miguel A. Garcia-Gonzalez, Alessia Bagattin, Magali Chiral, Serge Garbay, Claire Carette, Marco Pontoglio, Yann Herault, Michel Leibovici, Cécile Madaras

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6, pp.33087. ⟨10.1038/srep33087⟩
Scientific Reports, 2016, 6, pp.33087. ⟨10.1038/srep33087⟩
Scientific Reports, Nature Publishing Group, 2016, 6, pp.33087. 〈10.1038/srep33087〉

International audience; Maturity Onset Diabetes of the Young type 3 (MODY3), linked to mutations in the transcription factor HNF1A, is the most prevalent form of monogenic diabetes mellitus. HNF1alpha-deficiency leads to defective insulin secretion v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772198d4ee83ff9e042975fa5bab2bbf
https://doi.org/10.1038/srep33087

A survival-reproduction trade-off in entomopathogenic nematodes mediated by their bacterial symbionts

Autor: Vanya, Emelianoff, Elodie, Chapuis, Nathalie, Le Brun, Magali, Chiral, Catherine, Moulia, Jean-Baptiste, Ferdy

Publikováno v: Evolution; international journal of organic evolution. 62(4)

In this work, we investigate the investment of entomopathogenic Steinernema nematodes (Rhabditidae) in their symbiotic association with Xenorhabdus bacteria (Enterobacteriaceae). Their life cycle comprises two phases: (1) a free stage in the soil, wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a085acee1e2a31e8549fb38a510cbd9b
https://pubmed.ncbi.nlm.nih.gov/18194474