Safety, pharmacokinetics, and pharmacodynamics of escalating repeat doses of GSK249320 in patients with stroke

Autor: Cramer, Steven C, Abila, Bams, Scott, Nicola E, Simeoni, Monica, Enney, Lori A, MAG111539 Study Investigators

Publikováno v: Cramer, Steven C; Abila, Bams; Scott, Nicola E; Simeoni, Monica; Enney, Lori A; & MAG111539 Study Investigators,. (2013). Safety, pharmacokinetics, and pharmacodynamics of escalating repeat doses of GSK249320 in patients with stroke.. Stroke, 44(5), 1337-1342. doi: 10.1161/strokeaha.111.674366. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/58g5v86f

Restorative therapies have the potential to improve function and reduce disability after stroke with a wide therapeutic window. The current study evaluated GSK249320, a monoclonal antibody that blocks the axon outgrowth inhibition molecule myelin-ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::b55c49b971835c22ece75ec5bd2e1ee4
http://www.escholarship.org/uc/item/58g5v86f

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New Directions in Treatments Targeting Stroke Recovery.

Autor: Lin, David J., Finklestein, Seth P., Cramer, Steven C.

Publikováno v: Stroke (00392499); Dec2018, Vol. 49 Issue 12, p3107-3114, 8p

Proof-of-Concept Randomized Trial of the Monoclonal Antibody GSK249320 Versus Placebo in Stroke Patients.

Autor: Cramer, Steven C., Enney, Lori A., Russell, Colleen K., Simeoni, Monica, Thompson, Thomas R.

Publikováno v: Stroke (00392499); Mar2017, Vol. 48 Issue 3, p692-698, 7p, 1 Diagram, 4 Charts, 1 Graph