Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death: an individual participant-level data meta-analysis

Autor: Milad Nazarzadeh, Morris J. Brown, Anthony Rodgers, Henry R. Black, Takao Saruta, Hiromichi Suzuki, Sverre E. Kjeldsen, Barry R. Davis, Anushka Patel, Edmund J. Lewis, John B. Kostis, Stevo Julius, Giuseppe Remuzzi, Jan A. Staessen, Stephan Lueders, Lutgarde Thijs, Ji-Guang Wang, Jan Lanke, Rory Collins, Amanda I Adler, Ray Estacio, Gianpaolo Reboldi, Yoshiki Yui, Yoshihiko Kanno, Michel Lievre, Ajay Gupta, Hiroshi Ogawa, Piero Ruggenenti, Maria H Mehlum, Peter Sleight, Craig S. Anderson, Tsuguya Fukui, Ale Algra, Jamie P. Dwyer, William C. Cushman, MA Pfeffer, Ettore Malacco, Julia B. Lewis, Kenji Ueshima, Peter S. Sever, Lars H Lindholm, Steven E. Nissen, Larry Agodoa, Dexter Canoy, Christopher J. Bulpitt, Robert P Byington, Zeinab Bidel, Richard J McManus, Giancarlo Viberti, N Beckett, Jasper J Brugts, Eivind Berge, Frank P. Brouwers, Jacobus Lubsen, Robert W. Schrier, Johan Sundström, Salim Yusuf, Lindon Wing, Zhen-Yu Zhang, Paul K. Whelton, Colin Baigent, Alberto Zanchetti, Toshio Ogihara, Barry M. Brenner, Jeffrey Cutler, Bruce Neal, Paolo Verdecchia, Dick de Zeeuw, Stephen MacMahon, Takayoshi Ohkubo, Emma Copland, Wiek H. van Gilst, Folkert W. Asselbergs, Neil R Poulter, Kristian Wachtell, Vlado Perkovic, Kazem Rahimi, Christopher M. Reid, Peter M. Rothwell, Seiji Umemoto, Hiromi Rakugi, Koon K. Teo, Kim Fox, Malgorzata Wamil, Masao Ishii, Mark Woodward, Fiona Turnbull, Kizuku Kuramoto, Richard B Devereaux, Christopher R. Palmer, Joachim Schrader, Carl J. Pepine, Robert Fagard, Giuseppe Mancia, Rury R. Holman, Masunori Matsuzaki, Eric Boersma, John Chalmers, Jeannette Majert, Gholamreza Salimi-Khorshidi, Bertram Pitt, Yutaka Imai

Publikováno v: The Lancet, 398(10305), 1053-1064. Elsevier Ltd.

Background The effects of pharmacological blood-pressure-lowering on cardiovascular outcomes in individuals aged 70 years and older, particularly when blood pressure is not substantially increased, is uncertain. We compared the effects of blood-press

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32b7994875e1d4ad1d2b712dd71cf4f
https://doi.org/10.1016/s0140-6736(21)01921-8

Renal function estimation and Cockroft-Gault formulas for predicting cardiovascular mortality in population-based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: The Heart 'OMics' in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives

Autor: João Pedro Ferreira, Girerd N, Pellicori P, Duarte K, Girerd S, Ma, Pfeffer, Jj, Mcmurray, Pitt B, Dickstein K, Jacobs L, Ja, Staessen, Butler J, Latini R, Masson S, Mebazaa A, Hp, Rocca, Delles C, Heymans S, Sattar N, Jw, Jukema

Publikováno v: Europe PubMed Central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::755a44fdaf3e30fe3ba2cdaa2700cfa1
http://europepmc.org/abstract/med/27829460

Natural Language Processing to Adjudicate Heart Failure Hospitalizations in Global Clinical Trials.

Autor: Marti-Castellote PM; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA; Cardiovascular Disease Initiative, Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA., Reeder C; Cardiovascular Disease Initiative, Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA; Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA., Claggett BL; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA., Singh P; Cardiovascular Disease Initiative, Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA; Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA., Lau ES; Cardiovascular Disease Initiative, Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA; Division of Cardiology, Massachusetts General Hospital, Boston, MA., Khurshid S; Cardiovascular Disease Initiative, Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA; Demoulas Center for Cardiac Arrhythmias, Massachusetts General Hospital, Boston, MA., Batra P; Cardiovascular Disease Initiative, Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA; Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA., Lubitz SA; Cardiovascular Disease Initiative, Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA; Demoulas Center for Cardiac Arrhythmias, Massachusetts General Hospital, Boston, MA., Maddah M; Cardiovascular Disease Initiative, Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA; Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA., Vardeny O; Minneapolis VA Hospital, University of Minnesota, Minneapolis, MN., Lewis EF; Stanford University School of Medicine, Palo Alto, CA., Pfeffer MA; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA., Jhund PS; British Heart Foundation Cardiovascular Research Centre, University of Glasgow, United Kingdom., Desai AS; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA., McMurray JJV; British Heart Foundation Cardiovascular Research Centre, University of Glasgow, United Kingdom., Ellinor PT; Cardiovascular Disease Initiative, Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA; Demoulas Center for Cardiac Arrhythmias, Massachusetts General Hospital, Boston, MA., Ho JE; Cardiovascular Disease Initiative, Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA; CardioVascular Institute and Division of Cardiology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA., Solomon SD; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA., Cunningham JW; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA; Cardiovascular Disease Initiative, Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA.

Publikováno v: Circulation. Heart failure [Circ Heart Fail] 2024 Nov 16. Date of Electronic Publication: 2024 Nov 16.

Angiotensin Receptor Neprilysin Inhibition and Cardiovascular Outcomes Across the Kidney Function Spectrum: The PARAGON-HF Trial.

Autor: Mc Causland FR; Renal Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA. Electronic address: fmccausland@bwh.harvard.edu., Vaduganathan M; Harvard Medical School, Boston, Massachusetts, USA; Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Claggett B; Harvard Medical School, Boston, Massachusetts, USA; Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Gori M; Cardiology Division, Cardiovascular Department, Azienda Ospedaliera Papa Giovanni XXIII Hospital, Bergamo, Italy., Jhund PS; British Heart Foundation Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom., McGrath MM; Renal Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA., Neuen BL; George Institute for Global Health, UNSW Sydney, Sydney, New South Wales, Australia; Department of Renal Medicine, Royal North Shore Hospital, Sydney, New South Wales, Australia., Packer M; Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, Texas, USA., Pfeffer MA; Harvard Medical School, Boston, Massachusetts, USA; Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Rouleau JL; Institut de Cardiologie de Montréal, Université de Montréal, Montreal, Quebec, Canada., Senni M; Cardiology Division, Cardiovascular Department, Azienda Ospedaliera Papa Giovanni XXIII Hospital, Bergamo, Italy., Swedberg K; Department of Molecular and Clinical Medicine, University of Gothenburg, Sweden., Zannad F; Inserm CIC1433, CHRU de Nancy, Université de Lorraine, Nancy, France., Zile M; Medical University of South Carolina, Charleston, South Carolina, USA; Ralph H. Johnson Department of Veterans Affairs Medical Center, Charleston, South Carolina, USA., Lefkowitz MP; Novartis Pharmaceuticals, East Hanover, New Jersey, USA., McMurray JJV; British Heart Foundation Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom., Solomon SD; Harvard Medical School, Boston, Massachusetts, USA; Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

Publikováno v: JACC. Heart failure [JACC Heart Fail] 2024 Nov 06. Date of Electronic Publication: 2024 Nov 06.

Testing and Evaluation of Health Care Applications of Large Language Models: A Systematic Review.

Autor: Bedi S; Department of Biomedical Data Science, Stanford School of Medicine, Stanford, California., Liu Y; Clinical Excellence Research Center, Stanford University, Stanford, California., Orr-Ewing L; Clinical Excellence Research Center, Stanford University, Stanford, California., Dash D; Clinical Excellence Research Center, Stanford University, Stanford, California.; Center for Biomedical Informatics Research, Stanford University, Stanford, California., Koyejo S; Department of Computer Science, Stanford University, Stanford, California., Callahan A; Center for Biomedical Informatics Research, Stanford University, Stanford, California., Fries JA; Center for Biomedical Informatics Research, Stanford University, Stanford, California., Wornow M; Center for Biomedical Informatics Research, Stanford University, Stanford, California., Swaminathan A; Center for Biomedical Informatics Research, Stanford University, Stanford, California., Lehmann LS; Department of Medicine, Harvard Medical School, Boston, Massachusetts., Hong HJ; Department of Anesthesiology, Stanford University, Stanford, California., Kashyap M; Stanford University School of Medicine, Stanford, California., Chaurasia AR; Center for Biomedical Informatics Research, Stanford University, Stanford, California., Shah NR; Clinical Excellence Research Center, Stanford University, Stanford, California., Singh K; Digital Health Innovation, University of California San Diego Health, San Diego., Tazbaz T; Digital Health Center of Excellence, US Food and Drug Administration, Washington, DC., Milstein A; Clinical Excellence Research Center, Stanford University, Stanford, California., Pfeffer MA; Department of Medicine, Stanford University School of Medicine, Stanford, California., Shah NH; Clinical Excellence Research Center, Stanford University, Stanford, California.; Center for Biomedical Informatics Research, Stanford University, Stanford, California.

Publikováno v: JAMA [JAMA] 2024 Oct 15. Date of Electronic Publication: 2024 Oct 15.