Zobrazeno 1 - 10
of 858
pro vyhledávání: '"M1 macrophages"'
Publikováno v:
Сибирский научный медицинский журнал, Vol 44, Iss 5, Pp 129-137 (2024)
The contribution of immunoregulatory cytokines to the formation of cold airway hyperresponsiveness in asthma patients is important for understanding approaches to therapy. Aim of the study was to investigate the interaction of tumor necrosis factor-a
Externí odkaz:
https://doaj.org/article/f3d17c1aa41548949b2a6fd1d0fbeb73
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Small extracellular vesicles (sEVs) have the ability to transfer genetic material between cells, but their role in mediating HBV infection and regulating M1 macrophages to promote immune evasion remains unclear. In this study, we utilized PM
Externí odkaz:
https://doaj.org/article/f87a085529ea456083fd96ea64f128aa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease marked by inflammatory cell infiltration and joint damage. The Chinese government has approved the prescription medication sinomenine (SIN), an effective anti-inflammation dr
Externí odkaz:
https://doaj.org/article/cdbad307da8a466984808d477adf7b88
Autor:
Wenting Wang, Fengchun Wan, Tianxi Yu, Shuang Wu, Xin Cui, Chongjun Xiang, Monong Li, Qingzuo Liu, Chunhua Lin
Publikováno v:
BMC Biotechnology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background This study compared the differences of microvesicles (MVs) and microvesicles-delivering Smad7 (Smad7-MVs) on macrophage M1 polarization and fibroblast differentiation in a model of Peyronie’s disease (PD). Methods Overexpression
Externí odkaz:
https://doaj.org/article/20539762a0034df38f9e9cea3f1a803c
Autor:
Yaqian Cheng, Lulu Liu, Yufei Ye, Yingxue He, Wenwen Hu, Haiyan Ke, Zhi-Yong Guo, Guojian Shao
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
LN is a serious complication of systemic lupus erythematosus (SLE), affecting up to 60% of patients with SLE and may lead to end-stage renal disease (ESRD). Macrophages play multifaceted roles in the pathogenesis of LN, including clearance of immune
Externí odkaz:
https://doaj.org/article/417cd0d81eca4aeeb925f43403a93bf5
Autor:
Kaisong Huang, Haijin Zhou, Mei Chen, Rui Chen, Xiaoping Wang, Qi Chen, Zhiyun Shi, Yanfang Liang, Luxin Yu, Ping Ouyang, Li Li, Dan Jiang, Guangxian Xu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Tuberculosis(TB), an infectious disease caused by Mycobacterium tuberculosis (Mtb) infections, remains the leading cause of mortality from a single infectious agent globally. The progression of tuberculosis disease is contingent upon the complex inte
Externí odkaz:
https://doaj.org/article/f03b172d4ec54a049abfa8a0b7e31ed3
Autor:
Emanuel Quartin, Susana Rosa, Sara Gonzalez-Anton, Laura Mosteo Lopez, Vitor Francisco, Delfim Duarte, Cristina Lo Celso, Ricardo Pires das Neves, Lino Ferreira
Publikováno v:
Bioactive Materials, Vol 34, Iss , Pp 311-325 (2024)
More effective approaches are needed in the treatment of blood cancers, in particular acute myeloid leukemia (AML), that are able to eliminate resistant leukemia stem cells (LSCs) at the bone marrow (BM), after a chemotherapy session, and then enhanc
Externí odkaz:
https://doaj.org/article/0ce74d83bac54803992be667dee97677
Autor:
Ting Zhan, Yanli Zou, Zheng Han, XiaoRong Tian, Mengge Chen, Jiaxi Liu, Xiulin Yang, Qingxi Zhu, Meng Liu, Wei Chen, Mingtao Chen, Xiaodong Huang, Jie Tan, Weijie Liu, Xia Tian
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 8, Pp n/a-n/a (2024)
Abstract Aim The main focus of this study is to explore the molecular mechanism of IRF7 regulation on RPS18 transcription in M1‐type macrophages in pancreatic adenocarcinoma (PAAD) tissue, as well as the transfer of RPS18 by IRF7 via exosomes to PA
Externí odkaz:
https://doaj.org/article/832ea741bd344f789a6f40615ec68b92
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Idiopathic pulmonary fibrosis (IPF) is a lung disease that worsens over time, causing fibrosis in the lungs and ultimately resulting in respiratory failure and a high risk of death. Macrophages play a crucial role in the immune system, showing flexib
Externí odkaz:
https://doaj.org/article/778483c7e72245ed812548819e3a933f
Autor:
Bo Yang, Sanhua Hang, Siting Xu, Yun Gao, Wenhua Yu, Guangyao Zang, Lili Zhang, Zhongqun Wang
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32073- (2024)
Atherosclerosis is a chronic inflammatory disease characterised by plaque accumulation in the arteries. Macrophages are immune cells that are crucial in the development of atherosclerosis. Macrophages can adopt different phenotypes, with the M1 pheno
Externí odkaz:
https://doaj.org/article/e13f18942e3e4338b873db827a5d8fff