Zobrazeno 1 - 10
of 39
pro vyhledávání: '"M.W.A.C. Hukkelhoven"'
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 276:189-196
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b13bb56b9b671d70ff6c3f8d9700f0
https://doi.org/10.1016/s0378-4347(00)85081-1
https://doi.org/10.1016/s0378-4347(00)85081-1
Autor:
M.W.A.C. Hukkelhoven, Alphons J.M. Vermorken, Lisette W.M. Vromans, Frank N.A.M. van Pelt, Rob A.C. Keulers
Publikováno v:
Cancer Letters. 23:135-143
Five low-dose applications of a commercial coal tar preparation on a small scalp skin region resulted in an induction of aryl hydrocarbon hydroxylase (AHH) activity in freshly isolated human hair follicles. Large but reproducible interindividual diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5993f26f8134e455ff4cb281e976c3
https://doi.org/10.1016/0304-3835(84)90146-0
https://doi.org/10.1016/0304-3835(84)90146-0
Publikováno v:
Toxicology Letters. 17:7-12
Freshly isolated hair follicles of 20 adult non-smoking volunteers were assayed for formation of phenolic and dihydrodiol metabolites of benzo(a)pyrene (BP). In each of a total of 14 experiments two volunteers were assayed simultaneously, and the rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a96c427b9416e7b3141833e291b0f1
https://doi.org/10.1016/0378-4274(83)90028-0
https://doi.org/10.1016/0378-4274(83)90028-0
Publikováno v:
Archives of Toxicology. 57:6-12
Primary cultures of human hair follicle keratinocytes were established by using a basement membrane-like growth substrate, the bovine eye lens capsule. A method was adapted for the isolation of 3H-benzo(a)pyrene (BP)-modified DNA from the cellular ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc155698c9fe331ac5ce7fb3f5b5123
https://doi.org/10.1007/bf00286567
https://doi.org/10.1007/bf00286567
Publikováno v:
Cancer Letters. 31:105-112
A fluorometric assay for determination of glutathione-S-epoxide transferase (GSH-T) activity in freshly isolated human hair follicles or cultured cells is described. With this assay, basal levels of the enzyme in hair follicles have been compared bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005d171a983f86fded55380f2ce91c7a
https://doi.org/10.1016/0304-3835(86)90172-2
https://doi.org/10.1016/0304-3835(86)90172-2
Publikováno v:
Ophthalmic Research. 11:283-287
Polygonally shaped epithelial lens cells show elongation upon subculturing. As a result cytoskeletal structures change in relative abundancy. A cytoskeletal constituent, occurring in the perinuclear p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c0f3af5d515e15fdeb9af29b0126b2b
https://doi.org/10.1159/000265020
https://doi.org/10.1159/000265020
Autor:
M.W.A.C. Hukkelhoven, Hans Bloemendal, Ap A. Groeneveld, Johannes A. Lenstra, P.J.J.M. Weterings, R. A. M. M. Smits
Publikováno v:
Experimental Eye Research. 35:549-554
In addition to our SV40-transformed hamster cell line (Bloemendal et al. 1980), two otherlenticular cell lines have been established. One was obtained by transformation of hamster lens cells with the carcinogen 3-methylcholanthrene, the other one by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125c1f322f711a535ed0f2799677873a
https://doi.org/10.1016/s0014-4835(82)80069-9
https://doi.org/10.1016/s0014-4835(82)80069-9
Publikováno v:
Experimental Eye Research. 33:345-350
Bovine lens epithelium contains an enzyme system that metabolizes the carcinogen benzo(a)-pyrene. The major ethylacetate-soluble metabolites are 7,8-dihydro-7,8-dihydroxybenzo(a)-pyrene, 9,10-dihydro-9,10-dihydroxybenzo(a)pyrene and 3-hydroxybenzo(a)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ac0738610b4f91af831db689f8b701
https://doi.org/10.1016/s0014-4835(81)80057-7
https://doi.org/10.1016/s0014-4835(81)80057-7
Publikováno v:
FEBS Letters. (1):104-108
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0303f2dba3b1a0ca12469f3109d29281
Autor:
M.W.A.C. Hukkelhoven, A. M. G. Vermeesch-Markslag, Alphons J.M. Vermorken, P. Wirtz, J. Ziegenmeyer, C. M. A. A. Goos
Publikováno v:
Journal of Pharmacy and Pharmacology. 36:334-336
The effect of topical application of the androgen 5 alpha-dihydrotestosterone (DHT), both encapsulated in liposomes and solved in acetone, has been evaluated using the female hamster flank organ as a model system. Systemic absorption of DHT was signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97cf9d6b0cfeaa135e6095102c3f906d
https://doi.org/10.1111/j.2042-7158.1984.tb04387.x
https://doi.org/10.1111/j.2042-7158.1984.tb04387.x