Zobrazeno 1 - 10
of 96
pro vyhledávání: '"M.W. O'Donnell"'
Publikováno v:
Journal of Applied Toxicology. 32:722-730
Usnic acid, a natural botanical product, is a constituent of some dietary supplements used for weight loss. It has been associated with clinical hepatotoxicity leading to liver failure in humans. The present study was undertaken for metabolism and to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b01f39a0061c154743ede78050b8f2f
https://doi.org/10.1002/jat.1721
https://doi.org/10.1002/jat.1721
Publikováno v:
Journal of Applied Toxicology. 30:566-573
The present study was undertaken to assess, in vitro, the hepatotoxic potential of the food-borne mycotoxin, deoxynivalenol (DON), using rat (Clone9 and MH1C1), mouse (NBL CL2) and human (WRL68 and HepG2) liver cells in culture. The cells were treate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c772b0929a2427dc7c1d08ba07d3a5de
https://doi.org/10.1002/jat.1527
https://doi.org/10.1002/jat.1527
Autor:
Saura C. Sahu, Philip P. Sapienza, Thomas J. Flynn, M.W. O'Donnell, Chung S. Kim, Ivan A. Ross, Richard F. Newell, Paddy L. Wiesenfeld
Publikováno v:
Journal of Applied Toxicology. 28:703-709
Androstenedione, a naturally occurring steroid hormone, has been used to enhance athletic performance. Little is known, however, about its hepatotoxicity. Clone-9 cells, a non-transformed epithelial cell line that was originally isolated from normal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f8aec041f922b65eceeb00dee5cb5a
https://doi.org/10.1002/jat.1325
https://doi.org/10.1002/jat.1325
Autor:
Saura C. Sahu, P.P. Sapienza, Paddy Wiesenfeld, Thomas F.X. Collins, M.W. O'Donnell, C.E. Ford, Ivan A. Ross, Robert L. Sprando, Thomas J. Flynn, Chung S Kim
Publikováno v:
Food and Chemical Toxicology. 44:579-587
Androstenedione, a steroidal dietary supplement taken to enhance athletic performance, could affect serum and liver lipid metabolism, induce liver toxicity or alter inflammatory response depending on dose and duration of exposure. Pregnancy could fur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80fcf4783888503a863b13af928526a8
https://doi.org/10.1016/j.fct.2005.09.005
https://doi.org/10.1016/j.fct.2005.09.005
Autor:
P.P. Sapienza, Saura C. Sahu, Chung S Kim, Thomas F.X. Collins, M.W. O'Donnell, Ivan A. Ross, Robert L. Sprando, Thomas J. Flynn, Paddy Wiesenfeld
Publikováno v:
Food and Chemical Toxicology. 43:537-542
It is unknown whether androstenedione, a steroidal dietary supplement taken to enhance athletic performance, can affect physiological hormone levels by altering liver enzyme activities that metabolize steroid hormones. Altered hormone levels could be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7227d90af48bbaa8983b3237a7539b28
https://doi.org/10.1016/j.fct.2004.12.007
https://doi.org/10.1016/j.fct.2004.12.007
Autor:
P.P. Sapienza, Robert L. Sprando, Thomas J. Flynn, Paddy L. Wiesenfeld, M.W. O'Donnell, Saura C. Sahu, Thomas F.X. Collins, Chung S Kim, Ivan A. Ross
Publikováno v:
Food and Chemical Toxicology. 43:341-344
Androstenedione, a naturally occurring steroid hormone, is a dietary supplement used to enhance athletic performance. Little is known, however, about the safety of its use by young adults including women of child bearing age. To test the possible hep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bacba32b70cc1ab8348f5502e92f8547
https://doi.org/10.1016/j.fct.2004.11.005
https://doi.org/10.1016/j.fct.2004.11.005
Autor:
Nicholas Olejnik, Robert L. Sprando, Thomas J. Flynn, Paddy Wiesenfeld, T.N. Black, Uma S. Babu, M.W. O'Donnell, Thomas F.X. Collins
Publikováno v:
Food and Chemical Toxicology. 41:841-855
The effects of dietary flaxseed (FS), and defatted flaxseed meal (FLM) on serum and tissue fatty acid profiles were investigated. Pregnant Sprague–Dawley rats were fed AIN-93 based diets balanced in calories, fat, nitrogen, and fiber. Diets contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f15440ba13f8e3088f61b44e32fb4d0e
https://doi.org/10.1016/s0278-6915(03)00035-8
https://doi.org/10.1016/s0278-6915(03)00035-8
Autor:
Larry H. Garthoff, Arlen O. Sager, H.L. Dallas, L.H. Brown, R.K. Chi, H.M. Solomon, W.J. Trotter, S.J. Chirtel, V.P. Frattali, Curtis N. Barton, V.R. Bruce, R. O'Dell, J.W. Bier, Thomas J. Sobotka, M.A. Khan, M.W. O'Donnell, P.L. Poelma, G.R. Henderson, C.W. Thorpe
Publikováno v:
Food and Chemical Toxicology. 40:487-500
Toxicological effects of dietary soy trypsin inhibitor (TI) were assessed in male miniature swine, a model chosen for its similarities to human digestive physiology and anatomy. The TI preparation was extracted from defatted raw soy flour. From 1 thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3809d92e5ac16a28309c3ed60f07328e
https://doi.org/10.1016/s0278-6915(01)00120-x
https://doi.org/10.1016/s0278-6915(01)00120-x
Autor:
Saura C. Sahu, Curtis N. Barton, Ming W. Chou, Rene E. Sotomayor, Dennis M. Hinton, M.W. O'Donnell
Publikováno v:
Journal of Applied Toxicology. 20:215-219
Glutathione S-transferase (GST) plays a major role in the detoxification of the potent hepatocarcinogen aflatoxin B(1) (AFB(1)). This study evaluated the effects of intermittent exposures to AFB(1) on hepatic and testicular GST in rats. Male Fischer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98827a547a0a35c298a1235cbc80705f
https://doi.org/10.1002/(sici)1099-1263(200005/06)20:3<215::aid-jat649>3.0.co
https://doi.org/10.1002/(sici)1099-1263(200005/06)20:3<215::aid-jat649>3.0.co
Publikováno v:
Nutrition Research. 19:1637-1648
Because sugar alcohols can be used as bulk sweeteners and their possible lower energy values, interest has increased. Sorbitol and xylitol are hydrogenated monosaccharides that have widespread application. Male Fisher-344 rats were fed semipurified d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::895ffb6b812e47ae037a0f98464cafee
https://doi.org/10.1016/s0271-5317(99)00119-0
https://doi.org/10.1016/s0271-5317(99)00119-0