Výsledky vyhledávání - "M.V.W. Wijnands"

Effect of dietary galacto-oligosaccharides on azoxymethane-induced aberrant crypt foci and colorectal cancer in Fischer 344 rats

Autor: Ruud Woutersen, J.P. Bruijntjes, V.M.H. Hollanders, M.V.W. Wijnands, H.C. Schoterman

Publikováno v: Carcinogenesis, 1, 22, 127-132

The aim of the present study was to investigate the effects of galacto-oligosaccharides (GOS, Elix'or) on the development of aberrant crypt foci (ACF) and colorectal tumours in rats treated with azoxymethane (AOM). Two groups of 102 male Fischer 344

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7210596d66f34ad4cd34c468d3747e8c
https://doi.org/10.1093/carcin/22.1.127

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Dietary fat and carcinogenesis

Autor: A. van Garderen-Hoetmer, M.J. Appel, Ruud Woutersen, M.V.W. Wijnands

Publikováno v: Mutation Research, 443, 111-127

Epidemiologic investigations have suggested a relationship between dietary fat intake and various types of cancer incidences. Furthermore, epidemiologic studies as well as studies with animal models have demonstrated that not only the amount but also

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a959f250e7d8f3e13ecb3ba35cd6d6c
https://doi.org/10.1016/s1383-5742(99)00014-9

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Effect of saponin on the transmucosal passage of β-lactoglobulin across the proximal small intestine of normal and β-lactoglobulin-sensitised rats

Autor: Jean-Michel Wal, F. Grigoriadou, M.V.W. Wijnands, Ian T. Johnson, Jennifer M. Gee, A.M. Penninks, H. Atkinson, G.M. Wortley, K. Miller

Publikováno v: Toxicology. 117:219-228

The ability of saponins and glycoalkaloids to permeabilise the mammalian intestinal barrier has been previously demonstrated in vitro, leading to the hypothesis that membranolytic saponins may facilitate transfer to the tissues of otherwise excluded

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d146ba5e84e7a2fedf3408d6082833
https://doi.org/10.1016/s0300-483x(96)03574-3

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Do aberrant crypt foci have predictive value for the occurrence of colorectal tumours? Potential of gene expression profiling in tumours

Autor: C.A.M Krul, Ruud Woutersen, M. J. van Erk, M.V.W Wijnands, Robert Doornbos

Publikováno v: Food and Chemical Toxicology, 10, 42, 1629-1639
Food and Chemical Toxicology 42 (2004) 10
Food and Chemical Toxicology, 42(10), 1629-1639

The effects of different dietary compounds on the formation of aberrant crypt foci (ACF) and colorectal tumours and on the expression of a selection of genes were studied in rats. Azoxymethane-treated male F344 rats were fed either a control diet or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45584e3f54235d10358f458a2692c285
https://pubmed.ncbi.nlm.nih.gov/15304309

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A comparison of the effects of dietary cellulose and fermentable galacto-oligosaccharide, in a rat model of colorectal carcinogenesis: fermentable fibre confers greater protection than non-fermentable fibre in both high and low fat backgrounds

Autor: Ruud Woutersen, M.V.W. Wijnands, V.M.H. Hollanders, M.J. Appel

Publikováno v: Carcinogenesis, 4, 20, 651-656

The objective of this experiment was to compare the effects of diets with either a non-fermentable fibre source (cellulose) or a fermentable fibre source [galacto-oligosaccharide (GOS)], combined with different levels of dietary fat, on the developme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8ead2a67dbfa54649b9c59bfaea497
https://pubmed.ncbi.nlm.nih.gov/10223195

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Safety evaluation of phytosterol esters. Part 3. Two-generation reproduction study in rats with phytosterol esters - A novel functional food

Autor: M.V.W. Wijnands, D.H. Waalkens-Berendsen, P.A. Hepburn, A.P.M. Wolterbeek, M. Richold

Publikováno v: Food and Chemical Toxicology, 7, 37, 683-696

Phytosterol esters (PE) are intended for use as a novel food ingredient with plasma cholesterol lowering activity which works by inhibiting the absorption of cholesterol from the gut. Although PE are naturally present in the normal diet, the levels a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3601d931e1383915cfe44d9f3df60e7
http://resolver.tudelft.nl/uuid:aec257a8-a2d7-4c33-a682-50de10317c79

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