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pro vyhledávání: '"M.T. Palano"'
Akademický článek
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Autor:
William G. Stetler-Stevenson, Adriana Albini, Antonino Bruno, Douglas M. Noonan, Matteo Gallazzi, Riccardo Ricotta, M.T. Palano, Valentina Carlini
Publikováno v:
Cancers
Volume 13
Issue 19
Cancers, Vol 13, Iss 4955, p 4955 (2021)
Volume 13
Issue 19
Cancers, Vol 13, Iss 4955, p 4955 (2021)
Simple Summary Cancer patients are characterized by NK cells with altered surface markers, such as CD56 brightness, CD9, CD49a (pro-angiogenic) and PD-1, and TIM-3 (exhaustion), that favor immune escape. Transforming growth factor-beta (TGFβ) is a m
Therapeutic Regeneration of Lymphatic and Immune Cell Functions upon Lympho-organoid Transplantation
Autor:
Annapaola Andolfo, M.T. Palano, Sylvain Mukenge, Vincenzo Russo, Denise Drago, Luca Genovese, Antonello E. Spinelli, Elisa Lenti, Andrea Brendolan, Steven T. Proulx, Massimo Alfano, Silvia Bianchessi, Tatiana V. Petrova, Laura Raccosta
Publikováno v:
Stem Cell Reports, 12 (6)
Stem cell reports, vol. 12, no. 6, pp. 1260-1268
Lenti, Elisa; Bianchessi, Silvia; Proulx, Steven Thomas; Palano, Maria Teresa; Genovese, Luca; Raccosta, Laura; Spinelli, Antonello; Drago, Denise; Andolfo, Annapaola; Alfano, Massimo; Petrova, Tatiana V; Mukenge, Sylvain; Russo, Vincenzo; Brendolan, Andrea (2019). Therapeutic Regeneration of Lymphatic and Immune Cell Functions upon Lympho-organoid Transplantation. Stem cell reports, 12(6), pp. 1260-1268. Elsevier 10.1016/j.stemcr.2019.04.021
Stem Cell Reports, Vol 12, Iss 6, Pp 1260-1268 (2019)
Stem cell reports, vol. 12, no. 6, pp. 1260-1268
Lenti, Elisa; Bianchessi, Silvia; Proulx, Steven Thomas; Palano, Maria Teresa; Genovese, Luca; Raccosta, Laura; Spinelli, Antonello; Drago, Denise; Andolfo, Annapaola; Alfano, Massimo; Petrova, Tatiana V; Mukenge, Sylvain; Russo, Vincenzo; Brendolan, Andrea (2019). Therapeutic Regeneration of Lymphatic and Immune Cell Functions upon Lympho-organoid Transplantation. Stem cell reports, 12(6), pp. 1260-1268. Elsevier 10.1016/j.stemcr.2019.04.021
Stem Cell Reports, Vol 12, Iss 6, Pp 1260-1268 (2019)
Lymph nodes (LNs) are secondary lymphoid tissues that play a critical role in filtering the lymph and promoting adaptive immune responses. Surgical resection of LNs, radiation therapy, or infections may damage lymphatic vasculature and compromise imm
Autor:
Aurelia Lamanuzzi, Ilaria Saltarella, Arianna Brevi, Daniele Derudas, Patrizia Leone, Domenico Ribatti, Angelo Vacca, Franco Dammacco, Raffaella Chiaramonte, Ruggiero Fumarulo, Maria Addolorata Mariggiò, Lucia Di Marzo, Vito Racanelli, Vanessa Desantis, Roberto Ria, Maria Antonia Frassanito, M.T. Palano, Antonino Neri, Matteo Bellone
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 1, Pp 93-105 (2019)
Interactions of multiple myeloma (MM) cells with endothelial cells (ECs) enhance angiogenesis and MM progression. Here, we investigated the role of Notch signaling in the cross talk between ECs and MM cells enabling angiogenesis. MMECs showed higher
Autor:
M.T. Palano, Matteo Gallazzi, Antonino Bruno, Martina Cucchiara, Andrea De Lerma Barbaro, Lorenzo Mortara
Publikováno v:
Vaccines
Vaccines, Vol 9, Iss 1178, p 1178 (2021)
Vaccines, Vol 9, Iss 1178, p 1178 (2021)
Leukocytes often undergo rapid changes in cell phenotype, for example, from a resting to an activated state, which places significant metabolic demands on the cell. These rapid changes in metabolic demand need to be tightly regulated to support immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cb0af9bd68ad0c9c1e04d9915d6f5a
http://hdl.handle.net/11383/2119106
http://hdl.handle.net/11383/2119106
Autor:
Ilaria Saltarella, Giovanni Vitale, Elisa Taiana, Germano Gaudenzi, Monica Falleni, Natalia Platonova, Antonino Neri, Domenica Giannandrea, Delfina Tosi, Valentina Citro, Raffaella Chiaramonte, Elena Lesma, Nicola Amodio, Roberto Ria, Michela Colombo, M.T. Palano
Publikováno v:
Cancers
Volume 12
Issue 9
Cancers, Vol 12, Iss 2600, p 2600 (2020)
Volume 12
Issue 9
Cancers, Vol 12, Iss 2600, p 2600 (2020)
Multiple myeloma (MM) is an incurable plasma cell malignancy arising primarily within the bone marrow (BM). During MM progression, different modifications occur in the tumor cells and BM microenvironment, including the angiogenic shift characterized
Akademický článek
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Akademický článek
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Autor:
M. Lancellotti, Michela Colombo, Anna Pistocchi, Andrea Basile, S. Garavelli, Mara Mazzola, M.T. Palano, Raffaella Colella, Marzia Barbieri, L. Apicella, Raffaella Chiaramonte, Mauro Turrini, Elisa Taiana, Natalia Platonova, Elisa Lazzari, Domenica Giannandrea, Antonino Neri, Elena Lesma, Silvia Ancona
Publikováno v:
Haematologica
Multiple myeloma is still incurable due to an intrinsic aggressiveness or, more frequently, to the interactions of malignant plasma cells with the bone marrow (BM) microenvironment. Myeloma cells educate BM cells to support neoplastic cell growth, su
Autor:
S. Garavelli, Antonino Neri, Leslie Crews, Catriona Jamieson, S. Galletti, M.T. Palano, Michela Colombo, Elisa Lazzari, Natalia Platonova, F. Baccianti, Raffaella Chiaramonte
Publikováno v:
Cancer Research. 77:LB-025
The aim of this study was to investigate the role of Notch signaling in intrinsic and bone marrow stromal cells (BMSC)-mediated drug resistance in multiple myeloma (MM) and in MM-stem cell (SC) niche maintenance. MM is an incurable hematological mali