Zobrazeno 1 - 10
of 169
pro vyhledávání: '"M.T. Greenwood"'
Autor:
Yiheng Chen, Guillaume Butler-Laporte, Kevin Y.H. Liang, Yann Ilboudo, Summaira Yasmeen, Takayoshi Sasako, Claudia Langenberg, Celia M.T. Greenwood, J. Brent Richards
Publikováno v:
HGG Advances, Vol 5, Iss 4, Pp 100344- (2024)
Summary: A novel algorithm, AlphaMissense, has been shown to have an improved ability to predict the pathogenicity of rare missense genetic variants. However, it is not known whether AlphaMissense improves the ability of gene-based testing to identif
Externí odkaz:
https://doaj.org/article/583c788363d4437abde5738bc7ea141b
Autor:
Karen Gambaro, Maud Marques, Suzan McNamara, Mathilde Couetoux du Tertre, Zuanel Diaz, Cyrla Hoffert, Archana Srivastava, Steven Hébert, Benoit Samson, Bernard Lespérance, Yoo‐Joung Ko, Richard Dalfen, Eve St‐Hilaire, Lucas Sideris, Felix Couture, Ronald Burkes, Mohammed Harb, Errol Camlioglu, Adrian Gologan, Vincent Pelsser, André Constantin, Celia M.T. Greenwood, Sabine Tejpar, Petr Kavan, Claudia L. Kleinman, Gerald Batist
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 4, Pp n/a-n/a (2021)
Abstract Background Therapeutic resistance is the main cause of death in metastatic colorectal cancer. To investigate genomic plasticity, most specifically of metastatic lesions, associated with response to first‐line systemic therapy, we collected
Externí odkaz:
https://doaj.org/article/2db15e511b2048da941740287e8636c1
Publikováno v:
Biological Psychiatry. 93:82-91
There is a pressing need for novel drug targets for psychiatric disorders. Circulating proteins are potential candidates because they are relatively easy to measure and modulate and play important roles in signaling.We performed two-sample Mendelian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f93474c8ea72e6e40b532b633d8d10
https://doi.org/10.1016/j.biopsych.2022.08.015
https://doi.org/10.1016/j.biopsych.2022.08.015
Autor:
Marie Forest, Kieran J. O'Donnell, Greg Voisin, Helene Gaudreau, Julia L. MacIsaac, Lisa M. McEwen, Patricia P. Silveira, Meir Steiner, Michael S. Kobor, Michael J. Meaney, Celia M.T. Greenwood
Publikováno v:
Epigenetics, Vol 13, Iss 1, Pp 19-32 (2018)
Epigenome-wide association studies (EWAS) have focused primarily on DNA methylation as a chemically stable and functional epigenetic modification. However, the stability and accuracy of the measurement of methylation in different tissues and extracti
Externí odkaz:
https://doaj.org/article/38e7a687521c4744bb54c7d66f98b099
Autor:
Tahsin Ferdous, Lai Jiang, Irina Dinu, Julie Groizeleau, Anita L. Kozyrskyj, Celia M.T. Greenwood, Marie-Claire Arrieta
Publikováno v:
Mucosal Immunology. 15:1060-1070
A priori power and sample size calculations are crucial to appropriately test null hypotheses and obtain valid conclusions from all clinical studies. Statistical tests to evaluate hypotheses in microbiome studies need to consider intrinsic features o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1620adcdf7911e65eff21ececa00b783
https://doi.org/10.1038/s41385-022-00548-1
https://doi.org/10.1038/s41385-022-00548-1
Publikováno v:
Genetics in Medicine. 24:1545-1555
The study aimed to evaluate whether polygenic risk scores could be helpful in addition to family history for triaging individuals to undergo deep-depth diagnostic sequencing for identifying monogenic causes of complex diseases.Among 44,550 exome-sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a55b3190edb0428278f1f5dc199cff6
https://doi.org/10.1016/j.gim.2022.03.022
https://doi.org/10.1016/j.gim.2022.03.022
Publikováno v:
Journal of Bone and Mineral Research. 37:1592-1602
New therapies may help to prevent osteoporotic fractures other than through increasing bone mineral density (BMD). Because fracture risk has an important genetic component, we aim to identify loci increasing fracture risk that do not decrease BMD, us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be953ff6759c79576753ff0f3817c10e
https://doi.org/10.1002/jbmr.4632
https://doi.org/10.1002/jbmr.4632
Autor:
Walter H. Gotlieb, Amber Yasmeen, Patricia N. Tonin, Susie Lau, Shannon Salvador, Leon C. Van Kempen, Celia M.T. Greenwood, Alex Ferenczy, Manuella Pelmus, Liron Kogan, Kathleen Klein, Roy Kessous, David Octeau
Gene expression values
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cce35281ce4a6ebc1a8d544128928ae
https://doi.org/10.1158/1541-7786.22513510.v1
https://doi.org/10.1158/1541-7786.22513510.v1
Autor:
Walter H. Gotlieb, Amber Yasmeen, Patricia N. Tonin, Susie Lau, Shannon Salvador, Leon C. Van Kempen, Celia M.T. Greenwood, Alex Ferenczy, Manuella Pelmus, Liron Kogan, Kathleen Klein, Roy Kessous, David Octeau
Differential expression results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f1b72862d33cd14ba6850472709c5c
https://doi.org/10.1158/1541-7786.22513507
https://doi.org/10.1158/1541-7786.22513507
Autor:
Walter H. Gotlieb, Amber Yasmeen, Patricia N. Tonin, Susie Lau, Shannon Salvador, Leon C. Van Kempen, Celia M.T. Greenwood, Alex Ferenczy, Manuella Pelmus, Liron Kogan, Kathleen Klein, Roy Kessous, David Octeau
Supplementary Figure 1: Log-transformed Quantile-Quantile plots of the Univariate Survival Analysis p-values. P-values derived from the univariate survival analysis of the effects of each individual gene was plotted for each fold in which the analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce03c59ffa6559d0419d103b832c905
https://doi.org/10.1158/1541-7786.22513522
https://doi.org/10.1158/1541-7786.22513522