Zobrazeno 1 - 10
of 124
pro vyhledávání: '"M.Steven Piver"'
Autor:
Kerry J. Rodabaugh, Carolyn Farrell, Richard A. DiCioccio, S. South, M.Steven Piver, Heidi Vance, Cathy Fahey
Publikováno v:
Cancer. 115:324-333
BACKGROUND: Inherited mutations account for approximately 10% of all epithelial ovarian cancers. Breast cancer (BRCA1 and BRACA2) gene mutations are responsible for up to 85% of inherited breast and/or ovarian cancer. Another condition that has been
Autor:
M.Steven Piver, Cathy Fahey, Jeannine A. Villella, Madhu Parmar, Kathleen A. Donohue, Kerry J. Rodabaugh
Publikováno v:
Gynecologic Oncology. 102:475-479
Background. Current surgical recommendations for ovarian cancer prophylaxis in women at high risk of developing ovarian cancer include bilateral salpingo-oophorectomy (risk-reducing salpingo-oophorectomy (RRSO)). The role of hysterectomy is unclear.
Autor:
M.Steven Piver
Publikováno v:
Gynecologic Oncology. 85:9-17
Autor:
Yoshiaki Tsukada, Kim Garlinghouse-Jones, Bruce A. Werness, Bruce A.J. Ponder, Susan J. Ramus, Richard A. DiCioccio, Alice S. Whittemore, Ingrid Oakley-Girvan, M.Steven Piver
Publikováno v:
Human Pathology. 31:1420-1424
Breast cancers from patients with germline BRCA1 mutations show characteristic histopathologic features. However, similar studies of BRCA1 -associated ovarian cancers have reported inconsistent findings. Interobserver differences in histopathologic c
Autor:
Bruce A.J. Ponder, Alice S. Whittemore, Ingrid Oakley-Girvan, Pankhuri Parvatiyar, Richard A. DiCioccio, Jonathan S. Wiest, Yoshiaki Tsukada, Kim Garlinghouse-Jones, Bruce A. Werness, Susan J. Ramus, M.Steven Piver
Publikováno v:
Journal of the National Cancer Institute. 92:1088-1091
Background The two-hit hypothesis for the genesis of cancer predicts that cancer can develop when the wild-type allele of a tumor suppressor gene is lost in an individual with a germline mutation in that gene. Neither loss of heterozygosity (LOH) for
Publikováno v:
Gynecologic Oncology. 77:377-382
The current study evaluated the effects of Flt-3 ligand (FL) on the growth of human malignant ovarian tumors engrafted in severe combined immunodeficient (SCID) mice with particular attention directed at FL's effect on the host natural killer (NK) ce
Publikováno v:
Gynecologic Oncology. 75:334-337
Objective. The aim of this study was to assess the role of first-line chemotherapy with paclitaxel and platinum in the treatment of advanced or recurrent cervix cancer. Methods. Twenty patients with advanced or recurrent cancer of the cervix with no
Publikováno v:
Obstetrics & Gynecology. 94:704-708
Objective: To assess the feasibility and complications of operative laparoscopy in women with high body mass indices (BMIs). Methods: Forty-seven consecutive patients with BMIs exceeding 30 who underwent operative laparoscopy were compared with 160 c
Autor:
Sharad A. Ghamande, M.Steven Piver
Publikováno v:
Journal of Surgical Oncology. 72:162-169
Background and Objectives We assessed the role of salvage chemotherapy with topotecan and cisplatin in patients with platinum- and paclitaxel-resistant advanced and recurrent ovarian or primary peritoneal cancer, based on the reported in vivo and in
Publikováno v:
Journal of Surgical Oncology. 72:9-13
Background and Objective The safety of laparoscopic surgery in women with a family history of ovarian cancer predicted to have benign disease has not been established. The objective of this study was to evaluate the feasibility and complications of o