Zobrazeno 1 - 10
of 77
pro vyhledávání: '"M.S. Leaning"'
Publikováno v:
IFAC Proceedings Volumes. 18:1613-1618
The nature and origin of clinical time series data are discussed. A number of model-based techniques of estimation and prediction are outlined and evaluated in worked examples. These examples are relevant to the management of disorders involving flui
Publikováno v:
Measurement. 2:187-190
Parameter estimates obtained by identification procedures may or may not be measurements of attributes in the system under study. It is argued that both a valid model and a well-posed identification problem are necessary conditions for such estimates
Publikováno v:
Transactions of the Institute of Measurement and Control. 5:87-98
Model valadity is a multi-faceted concept which is expressed as a set of validity criteria related to different modelling objectives. These criteria form the basis of a validation methodology for biological models - an integral part of the modelling
Autor:
M.S. Leaning, Ludwik Finkelstein
Publikováno v:
Measurement. 2:25-34
The paper surveys the current state of the theory of the fundamental concepts of measurement which is based on the model theory of logic. A brief review is given of the historical development of measurement theory. The model-theoretic definition of m
Publikováno v:
IFAC Proceedings Volumes. 21:583-587
The work to be described forms one part of a research project under the umbrella term of "Artificial Intelligence in Medicine." More specifically the domain of interest is Critical Care Medicine, where the area of concern is the care of patients who
Publikováno v:
IFAC Proceedings Volumes. 21:629-634
The paper presents a novel design for the computer modelling and simulation of the cardiovascular system based upon relational analysis. The advantage of this approach is that the model structure, assumptions and parameters are explicit and easily ch
Autor:
J.A. Summerfield, M.S. Leaning
Publikováno v:
IFAC Proceedings Volumes. 18:1403-1407
Glycoproteins terminated with mannose residues are cleared rapidly from plasma by a process of binding to surface receptors on hepatic sinusoidal cells with subsequent internalisation of the receptor ligand complex. The glycoprotein ligand is deliver
Publikováno v:
IEEE Transactions on Biomedical Engineering. :856-864
In this paper, a number of models which have been developed for studying fluid-electrolyte equilibrium and imbalance is presented. Two levels of dynamics and control are considered corresponding to the physiological processes and the incorporation of
Publikováno v:
IFAC Proceedings Volumes. 15:295-300
A mathematical model of the human renal and related subsystems, part of a systems approach to the management of renal dialysis patients, is described. The results of identifiability and parameter estimation procedures are presented - conducted to det
Autor:
M.S. Leaning, E. Nicolosi
Publikováno v:
IFAC Proceedings Volumes. 21:577-582
Qualitative simulation is an area of artificial intelligence which attempts to model the way humans think about physical systems. The paper presents the results of a reconstruction and critical evaluation of the QSIM algorithm (Kuipers, 1985), as app