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The combination of calcipotriol and methotrexate compared with methotrexate and vehicle in psoriasis: results of a multicentre placebo-controlled randomized trial

Autor: Bernard Guillot, Pierre Souteyrand, M.R. Klaber, Jean-Jacques Guilhou, Sarah Rogers, L. Barnes, J. Lauharanta, P.C.M. van de Kerkhof, Nils-Jørgen Mørk, Loïc Vaillant, M. De La Brassine, A. Ostrojic, Christer T. Jansén, M.M.B. Seijger, E.M.G.J. de Jong

Publikováno v: British Journal of Dermatology, 148, 2, pp. 318-25
British Journal of Dermatology, 148, 318-25

Item does not contain fulltext BACKGROUND: A multicentre, randomized, double-blind, vehicle-controlled, parallel-group study was carried out to study the effect of the addition of calcipotriol ointment to methotrexate (MTX) therapy in patients with p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98b3adf86dcfa9d777bf60d785941b5b
https://doi.org/10.1046/j.1365-2133.2003.05173.x

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Safety and efficacy of calcipotriol ointment (Dovonex®) in treating children with psoriasis vulgaris

Autor: C.R. Darley, N. Downes, C. Green, Peter E. Hutchinson, W.J. Cunliffe, M.R. Klaber

Publikováno v: British Journal of Dermatology. 135:390-393

Calcipotriol (Dovonex) ointment has been shown to be an effective, well tolerated, and acceptable treatment for psoriasis vulgaris in adults. This open study was conducted in 16 U.K. centres to assess the safety and efficacy of calcipotriol ointment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20861b9f587d70ed15b246be975ad929
https://doi.org/10.1111/j.1365-2133.1996.tb01501.x

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A multicentre 12-week open study of a lipid-soluble folate antagonist, piritrexim in severe psoriasis

Autor: W. Perkins, W.J. Cunliffe, R.E.A. Williams, M.R. Klaber, E.M. Saihan, A.M. Layton, V.K. Manna, M.J. Tidman, J.P. Vestey, H. Baker, R.M. Mackie

Publikováno v: British Journal of Dermatology. 129:584-589

Summary An open, 12-week, multicentre study was conducted to assess the efficacy of piritrexim isethionate in the treatment of severe psoriasis. Piritrexim isethionate is a lipid-soluble dihydrofolate reductase inhibitor which cannot form polyglutama

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38848786b6cf5c575e7f0945a1e441f
https://doi.org/10.1111/j.1365-2133.1993.tb00489.x

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Replacement of routine liver biopsy by procollagen III aminopeptide for monitoring patients with psoriasis receiving long-term methotrexate: a multicentre audit and health economic analysis

Autor: M Horan, M.R. Klaber, Catherine H. Smith, R.J.G. Chalmers, B. Kirby, P Burrows, J M Hextall, Sarah Rogers, A. Smith, R Little

Publikováno v: The British journal of dermatology. 152(3)

Summary Background Patients receiving long-term methotrexate for psoriasis are at risk of developing hepatic fibrosis. Repeated liver biopsy has long been regarded as the only reliable method of detecting this and it is still recommended by the Ameri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efbed8da7e8800d5ab601e9f4343b893
https://pubmed.ncbi.nlm.nih.gov/15787807

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Comparative effects of calcipotriol solution (50 micrograms/ml) and betamethasone 17-valerate solution (1 mg/ml) in the treatment of scalp psoriasis

Autor: N. Downess, M. S. Corbett, P.C.M. van de Kerkhof, M. K. Johnsson, L. Molin, Peter E. Hutchinson, Knud Kragballe, M.R. Klaber, A. Pedvis-Leftick, Timo Reunala

Publikováno v: The British journal of dermatology. 131(5)

The efficacy, tolerability and safety of calcipotriol solution and betamethasone 17-valerate solution were compared in a multicentre, prospective, randomized, double-blind, parallel group study. Four hundred and seventy-four patients with scalp psori

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be47ad798cbec44c335c2e93911d9532
https://pubmed.ncbi.nlm.nih.gov/7999600

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A multicentre, parallel-group comparison of calcipotriol ointment and short-contact dithranol therapy in chronic plaque psoriasis

Autor: M. Ganpule, S.J. Murray, M.R. Klaber, Anthony C. Chu, R.P. Haydey, W.A.H. Dodd, W.A.D. Griffiths, H.J. Jurgensen, S. Rogers, J. Berth-Jones

Publikováno v: The British journal of dermatology. 127(3)

Short-contact treatment with dithranol (anthralin) is a widely used treatment for chronic plaque psoriasis. Although effective, it causes staining and irritation, and is therefore inconvenient. Calcipotriol is a recently developed vitamin D analogue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1918d2ef6e3b6cd8e365a0388bc30242
https://pubmed.ncbi.nlm.nih.gov/1390171

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STRESSED TEMPLATE BLEEDING-TIME AND OTHER PLATELET-FUNCTION TESTS IN MYOCARDIAL INFARCTION

Autor: Sandra Jamieson, J.R. O'Brien, J.F. Ainsworth, M.D. Etherington, M.R. Klaber

Publikováno v: The Lancet. 301:694-696

Twenty-three male patients diagnosed in hospital as having myocardial infarction (M.I.) were examined 3 months to 5 years after discharge. They were compared with thirty-five apparently healthy male controls of the same age and social class. Measurem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53676ea8ed07832aaaee73c8b8c35fd6
https://doi.org/10.1016/s0140-6736(73)91481-5

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