ALTERATION IN MATRIX METALLOPROTEINASES (MMPS) ACTIVITY IN FIBROBLAST CELL LINE BY DEXAMETHASONE: A POSSIBLE MECHANISM IN CORTICOSTEROID-INDUCED GLAUCOMA

Autor: F. Saadat, A. Raji, K. Zomorodian M.B. Eslami, M. Pezeshki, M.R. Khorramizadeh Nastran Aalizadeh

Publikováno v: Iranian Journal of Allergy, Asthma and Immunology, Vol 2, Iss 3 (2003)

Corticosteroids are often used as anti-inflammatory agents in a variety of inflam¬matory diseases. It is well established that long-term administration of corticosteroids predisposed the patients to develop glaucoma. Although the exact pathophysiolo

Externí odkaz: https://doaj.org/article/6d768e476fbc4e75b488f348c6e8c665

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Angiotensin II induces NF-κB, JNK and p38 MAPK activation in monocytic cells and increases matrix metalloproteinase-9 expression in a PKC- andRho kinase-dependent manner

Autor: Mohsen Firoozrai, Soudabeh Fallah, M.R. Khorramizadeh, Hamid Yaghooti

Publikováno v: Brazilian Journal of Medical and Biological Research v.44 n.3 2011
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
Brazilian Journal of Medical and Biological Research, Volume: 44, Issue: 3, Pages: 193-199, Published: MAR 2011
Brazilian Journal of Medical and Biological Research, Vol 44, Iss 3, Pp 193-199 (2011)

Angiotensin II (ANG II), the main effector of the renin-angiotensin system, is implicated in endothelial permeability, recruitment and activation of the immune cells, and also vascular remodeling through induction of inflammatory genes. Matrix metall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad7b5ecaf74a3221fd864794f07d9c2
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000300003

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