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pro vyhledávání: '"M.R. Kaazempur-Mofrad"'
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Autor:
Clemens S. Fritsche, Oliver Simsch, Eli J. Weinberg, Jeffrey T. Borenstein, Brian K. Orrick, Joseph P. Vacanti, Roland Hetzer, Christof Stamm, M.R. Kaazempur-Mofrad
Publikováno v:
The International Journal of Artificial Organs. 32:701-710
Objectives The persistent shortage of donor organs for lung transplantation illustrates the need for new strategies in organ replacement therapy. Pulmonary tissue engineering aims at developing viable hybrid tissue for patients with chronic respirato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ed5a8f56d52c42acaaf4d10e9f080c
https://doi.org/10.1177/039139880903201001
https://doi.org/10.1177/039139880903201001
Autor:
M.R. Kaazempur-Mofrad, Jeffrey T. Borenstein, Wen-Ming Hsu, Katherine M. Kulig, Mark L. Miller, Eric F. Swart, Craig M. Neville, Eli J. Weinberg, A. Carraro, Wing Cheung, Joseph P. Vacanti
Publikováno v:
Biomedical Microdevices. 10:795-805
A novel microfluidics-based bilayer device with a discrete parenchymal chamber modeled upon hepatic organ architecture is described. The microfluidics network was designed using computational models to provide appropriate flow behavior based on physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c411ef8485946c5fb60b22f24482ebaa
https://doi.org/10.1007/s10544-008-9194-3
https://doi.org/10.1007/s10544-008-9194-3
Autor:
Joseph P. Vacanti, M.R. Kaazempur-Mofrad, Cathryn A. Sundback, Jeffrey T. Borenstein, Brian K. Orrick, Eli J. Weinberg
Publikováno v:
Tissue Engineering. 13:1837-1844
One of the principal challenges facing the field of tissue engineering over the past 2 decades has been the requirement for large-scale engineered constructs comprising precisely organized cellular microenvironments. For vital organ assist and replac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3482b28eb3daa0e477c1e0a9a916a9
https://doi.org/10.1089/ten.2006.0156
https://doi.org/10.1089/ten.2006.0156
Autor:
M.R. Kaazempur-Mofrad, Eli J. Weinberg
Publikováno v:
Journal of Biomechanics. 39:1557-1561
This paper presents a finite element formulation suitable for large-strain modeling of biological tissues and uses this formulation to implement an accurate finite element model for mitral valve leaflet tissue. First, an experimentally derived strain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576ab9179bec516c6d22998eca6b4218
https://doi.org/10.1016/j.jbiomech.2005.04.020
https://doi.org/10.1016/j.jbiomech.2005.04.020
Publikováno v:
International Journal of Heat and Mass Transfer. 48:4510-4517
Mass transport may play a significant role in the development of atherosclerosis, a progressive disease of the artery wall. In this work, advection-dominated transport of blood-borne components such as oxygen and ATP is considered in two arterial mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ac315f1bac0e53e94013cbd8689d316
https://doi.org/10.1016/j.ijheatmasstransfer.2005.05.004
https://doi.org/10.1016/j.ijheatmasstransfer.2005.05.004
Exploring the molecular basis for mechanosensation, signal transduction, and cytoskeletal remodeling
Publikováno v:
Acta Biomaterialia. 1:281-293
Living cells respond to mechanical stimulation in a variety of ways that affect nearly every aspect of their function. Such responses can range from changes in cell morphology to activation of signaling cascades and changes in cell phenotype. Althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e290e7897138d333334f9b5562736d8
https://doi.org/10.1016/j.actbio.2005.02.008
https://doi.org/10.1016/j.actbio.2005.02.008
Autor:
Eli J. Weinberg, M.R. Kaazempur-Mofrad
Publikováno v:
Cardiovascular Engineering. 5:37-43
Large-strain constitutive modeling of biological tissues has grown enormously as a field in the past decade. This paper investigates the viability of the existing models for describing heart valve leaflet mechanics. The properties of the leaflet tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1909c89249a0a53affb299dafb34703
https://doi.org/10.1007/s10558-005-3072-x
https://doi.org/10.1007/s10558-005-3072-x
Publikováno v:
American Journal of Physiology-Cell Physiology. 287:C954-C962
Vascular endothelial cells rapidly transduce local mechanical forces into biological signals through numerous processes including the activation of focal adhesion sites. To examine the mechanosensing capabilities of these adhesion sites, focal adhesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd746f567427eca4aa83b80879457d7
https://doi.org/10.1152/ajpcell.00567.2003
https://doi.org/10.1152/ajpcell.00567.2003
Autor:
A. G. Isasi, Raymond Chan, D. P. Hinton, M.R. Kaazempur-Mofrad, Glenn M. LaMuraglia, Richard T. Lee, Roger D. Kamm, Galina K. Sukhova, H.F. Younis
Publikováno v:
Annals of Biomedical Engineering. 32:932-946
Atherogenesis is known to be associated with the stresses that act on or within the arterial wall. Still, the uneven distribution of atherosclerotic lesions and the impact of vessel remodeling on disease progression are poorly understood. A methodolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5793f1613eabc87ab482e4ec6313e4
https://doi.org/10.1023/b:abme.0000032456.16097.e0
https://doi.org/10.1023/b:abme.0000032456.16097.e0