Zobrazeno 1 - 10
of 52
pro vyhledávání: '"M.O. Christen"'
Publikováno v:
Pathologie Biologie. 52:308-313
Les tendinopathies et les ruptures tendineuses sont des effets secondaires rencontres principalement chez des patients âges lors de traitements antibiotiques aux fluoroquinolones. Le but de notre travail a ete d'etudier l'effet de l'anethole dithiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16beaaab0cd8dc9a708ed2f8183cbe34
https://doi.org/10.1016/j.patbio.2003.11.001
https://doi.org/10.1016/j.patbio.2003.11.001
Publikováno v:
Toxicology in Vitro. 13:683-688
The mechanisms leading to tacrine (THA) hepatotoxic effects are not yet fully understood. Reactive oxygen species (ROS) overproduction and intracellular reduced glutathione (GSH) depletion are common mechanisms involved in drug toxicity. The aim of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d80860c7320f67ff891281ea8aee40
https://doi.org/10.1016/s0887-2333(99)00050-8
https://doi.org/10.1016/s0887-2333(99)00050-8
Publikováno v:
International Journal of Pharmaceutics. 129:295-299
First quantitative structure-activity relationships (QSAR) between electrophile detoxication properties of 1,2-dithiole-3-thiones and their log P values were checked. A very significant linear property was found with some disubstituted derivatives. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc1725b8f82974ab08bd6fa45802cb23
https://doi.org/10.1016/0378-5173(95)04260-1
https://doi.org/10.1016/0378-5173(95)04260-1
Publikováno v:
Life Sciences. 54:1947-1954
Gastrointestinal hormones, gastrin, cholecystokinin (CCK), and motilin, are known to induce contraction of digestive smooth muscle cells from various species. In this paper, we studied the effect of calcium channel blockers, diltiazem, nicardipine, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911d9b44ca895c2b09e666400f0f97b1
https://doi.org/10.1016/0024-3205(94)90129-5
https://doi.org/10.1016/0024-3205(94)90129-5
Publikováno v:
British Journal of Pharmacology. 99:374-378
1. Smooth muscle cells of the longitudinal muscle of the rabbit jejunum were dispersed by enzyme treatment and recordings of membrane current were made in the whole-cell mode by patch clamp technique. The action of pinaverium bromide on the voltage-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0829766c51384674ba8110828a87a8e4
https://doi.org/10.1111/j.1476-5381.1990.tb14711.x
https://doi.org/10.1111/j.1476-5381.1990.tb14711.x
Autor:
M.O. Christen
Publikováno v:
General Pharmacology: The Vascular System. 21:821-825
1. 1. The evidence reviewed here indicates that pinaverium bromide (Dicetel ® ) relaxes gastrointestinal (GI) structures primarily by inhibiting Ca 2+ influx through potential-dependent channels of surface membranes of smooth muscle cells. 2. 2. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8778a2717a1d58344851e438f267ea0
https://doi.org/10.1016/0306-3623(90)90439-s
https://doi.org/10.1016/0306-3623(90)90439-s
Publikováno v:
Cell calcium. 29(6)
The effects of L-type calcium channel blockers (CCBs) selective for the gastrointestinal tract (pinaverium) or non-selective (nicardipine and diltiazem), were investigated on CCK-, CCh- or KCl-induced contraction of smooth muscle cells (SMC) isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a76ff666641c3c532cb580280566c58
https://pubmed.ncbi.nlm.nih.gov/11352508
https://pubmed.ncbi.nlm.nih.gov/11352508
Publikováno v:
Fundamental and Clinical Pharmacology
Fundamental and Clinical Pharmacology, Wiley, 1997, 11, pp.231-236
Fundamental and Clinical Pharmacology, Wiley, 1997, 11, pp.231-236
The effects of pinaverium bromide on the stimulation of colonic motility induced by meal and cholecystokinin (CCK) were investigated in rats chronically fitted with intraparietal electrodes on the proximal colon and previously treated or not by capsa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::976bb023f93eb8985c5f5e26c172a5ce
https://pubmed.ncbi.nlm.nih.gov/9243254
https://pubmed.ncbi.nlm.nih.gov/9243254
Publikováno v:
Journal of pharmaceutical sciences. 84(9)
Water/n‐octanol partition coefficients (log P) for 33 1,2‐dithiole‐3‐thiones and for 18 1,2‐dithiol‐3‐ones were determined by RP‐HPLC measurement of the concentration of the solute in aqueous solution after equilibrium. Depending on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16613614e91d7ea73cb5c345cb4acfd7
https://pubmed.ncbi.nlm.nih.gov/8537890
https://pubmed.ncbi.nlm.nih.gov/8537890
Publikováno v:
Toxicology Letters. 144:s116-s117
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37029bd1cc6f9379cad0e6157b7bc0d1
https://doi.org/10.1016/s0378-4274(03)90431-0
https://doi.org/10.1016/s0378-4274(03)90431-0