Zobrazeno 1 - 10
of 26
pro vyhledávání: '"M.M. Huckabee"'
Autor:
Carla M. Sevin, Dawn C. Newcomb, R. Stokes Peebles, Wei Han, Kasia Goleniewska, Shinji Toki, M.M. Huckabee, Robert D. Collins, Kelli L. Boyd, Timothy S. Blackwell, Zhou Zhu, Taylor P. Sherrill, Madison G. Boswell
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 49:396-402
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, a multienzyme complex, is the major source for production of reactive oxygen species (ROS). ROS are increased in allergic diseases, such as asthma, but the role of ROS in disease pathogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac805cd4e1f0b4782f1297cb89356d6e
https://doi.org/10.1165/rcmb.2012-0442oc
https://doi.org/10.1165/rcmb.2012-0442oc
Autor:
William Lawson, Garret A. FitzGerald, Dawn C. Newcomb, Weisong Zhou, Shinji Toki, M.M. Huckabee, R. Stokes Peebles, Kasia Goleniewska
Publikováno v:
Journal of Leukocyte Biology. 94:77-88
PGI2 signaling through IP inhibits allergen-induced inflammatory responses in mice. We reported previously that PGI2 analogs decreased proinflammatory cytokine and chemokine production by mature BMDCs. However, whether PGI2 modulates the function of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea788f05d8283f0ec2137cd04957f7e2
https://doi.org/10.1189/jlb.1112559
https://doi.org/10.1189/jlb.1112559
Autor:
Dawn C. Newcomb, R. Stokes Peebles, Daniel E. Dulek, K. Goleniewska, Nicholas W. Lukacs, Sara Reiss, Jay K. Kolls, Madison G. Boswell, M.M. Huckabee
Publikováno v:
The Journal of Immunology. 188:1027-1035
IL-13 is a central mediator of airway hyperresponsiveness and mucus expression, both hallmarks of asthma. IL-13 is found in the sputum of patients with asthma; therefore, IL-13 is an attractive drug target for treating asthma. We have shown previousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab99d0aaae719c12733315ac85e38d66
https://doi.org/10.4049/jimmunol.1102216
https://doi.org/10.4049/jimmunol.1102216
Autor:
Sujin Lee, Carla D. Pretto, Dawn C. Newcomb, John V. Williams, Kate L. Stokes, Anne L. Hotard, Kaori Sakamoto, Kasia Goleniewska, Michael G. Currier, Martin L. Moore, R. Stokes Peebles, Michael H. Chi, M.M. Huckabee, Taylor P. Sherrill
Publikováno v:
Journal of Virology. 85:5782-5793
Airway mucus is a hallmark of respiratory syncytial virus (RSV) lower respiratory tract illness. Laboratory RSV strains differentially induce airway mucus production in mice. Here, we tested the hypothesis that RSV strains differ in pathogenesis by s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb36fd72c0d7a32d4961f5e5383eca7
https://doi.org/10.1128/jvi.01693-10
https://doi.org/10.1128/jvi.01693-10
Autor:
Ursula J. Buchholz, R. Stokes Peebles, Kasia Goleniewska, Peter L. Collins, Dawn C. Newcomb, Nicholas W. Lukacs, James E. Crowe, Cindy Luongo, Martin L. Moore, Vasiliy V. Polosukhin, M.M. Huckabee, John V. Williams, Michael H. Chi
Publikováno v:
Journal of Virology. 83:4185-4194
Respiratory syncytial virus (RSV) is the leading cause of respiratory failure and viral death in infants. Abundant airway mucus contributes to airway obstruction in RSV disease. Interleukin-13 (IL-13) is a mediator of pulmonary mucus secretion. It ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7714bc31b95bf215bcb6698643788270
https://doi.org/10.1128/jvi.01853-08
https://doi.org/10.1128/jvi.01853-08
Autor:
Huiyong Yin, Weisong Zhou, Shinji Toki, Subramaniam Sriram, Dustin R. Dowell, Chandramohan Natarajan, Madison G. Boswell, Richard M. Breyer, Dawn C. Newcomb, Pingsheng Wu, Matthew T. Lotz, M.M. Huckabee, R. Stokes Peebles, Kasia Goleniewska, Song-Yi Yao, Garret A. FitzGerald
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 5, p e33518 (2012)
PLoS ONE, Vol 7, Iss 5, p e33518 (2012)
Background Prostaglandin I2 (PGI2), a lipid mediator currently used in treatment of human disease, is a critical regulator of adaptive immune responses. Although PGI2 signaling suppressed Th1 and Th2 immune responses, the role of PGI2 in Th17 differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9625a5bf484bb5afa93cb8ace57e533a
http://europepmc.org/articles/PMC3349674
http://europepmc.org/articles/PMC3349674
Autor:
M.M. Huckabee, R. Stokes Peebles
Publikováno v:
Clinical and Molecular Allergy
Clinical and Molecular Allergy, Vol 7, Iss 1, p 2 (2009)
Clinical and Molecular Allergy : CMA
Clinical and Molecular Allergy, Vol 7, Iss 1, p 2 (2009)
Clinical and Molecular Allergy : CMA
Viruses are the predominant infectious cause of asthma exacerbations in the developed world. In addition, recent evidence strongly suggests that viral infections may also have a causal role in the development of childhood asthma. In this article, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece114ee54c7523cadc1ff1e29496e87
Autor:
Madison G. Boswell, Tina V. Hartert, John S. Markowitz, R.S. Peebles, M.M. Huckabee, Dawn C. Newcomb
Publikováno v:
Journal of Allergy and Clinical Immunology. 129:AB50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21ded7ad922c4e07562bdefe41f45218
https://doi.org/10.1016/j.jaci.2011.12.850
https://doi.org/10.1016/j.jaci.2011.12.850
Autor:
Jay K. Kolls, Weisong Zhou, Madison G. Boswell, K. Goleniewska, R. Stokes Peebles, Gurjit K. Khurana Hershey, Carla M. Sevin, Dawn C. Newcomb, M.M. Huckabee
Publikováno v:
Journal of Allergy and Clinical Immunology. 127:1006-1013.e4
Background IL-13 is a central mediator of airway responsiveness and mucus expression in patients with allergic airway inflammation, and IL-13 is currently a therapeutic target for asthma. However, little is known about how IL-13 regulates human CD4 +
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1067313b811802cbcd48199f11acbf1
https://doi.org/10.1016/j.jaci.2010.11.043
https://doi.org/10.1016/j.jaci.2010.11.043
Autor:
R.S. Peebles, Carla M. Sevin, Timothy S. Blackwell, Dawn C. Newcomb, M.M. Huckabee, K. Goleniewska
Publikováno v:
Journal of Allergy and Clinical Immunology. 127:AB259-AB259
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4d656dfc7f6e9b26851f80cb10e0e86
https://doi.org/10.1016/j.jaci.2010.12.1033
https://doi.org/10.1016/j.jaci.2010.12.1033