Zobrazeno 1 - 5
of 5
pro vyhledávání: '"M.Luisa Suárez-Gea"'
Publikováno v:
Tetrahedron Letters. 43:1421-1424
The synthesis of branched peptides from cyanomethylenamino pseudopeptides, via catalytic hydrogenation in the presence of amino acid derivatives, is described. When the inserted amino acid was a glycine derivative, the resulting branched peptide lact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::614734c733fcd8b72e609d03609243ae
https://doi.org/10.1016/s0040-4039(02)00012-6
https://doi.org/10.1016/s0040-4039(02)00012-6
Autor:
M. Teresa García-López, Rosario González-Muñiz, M.Luisa Suárez-Gea, A. Barber, Joaquín Del Río, Santiago Ballaz, Ana Fortuño, Susana Herrero, Rosario Herranz
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:855-860
The synthesis, binding to CCK receptors, and in vitro functional activity of pseudopeptide CCK-4 analogues incorporating the ( R ) or ( S ) Ψ[CH(CN)NH] peptide bond surrogate at the NIe 31 -Asp 32 or or Trp 30 -NIe 13 bonds are described. Z-TrpΨ[(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::571d7054d0b9ab24834086b9707b571b
https://doi.org/10.1016/s0960-894x(97)00107-8
https://doi.org/10.1016/s0960-894x(97)00107-8
Publikováno v:
The Journal of Organic Chemistry. 59:3600-3603
A general procedure for the preparation of (carbamoylmethylene)amino pseudopeptides from the corresponding (cyanonaethylenene)amino analogues, compatible with peptide bonds and with the usual amino and carboxyl protecting groups, is described. This p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5daf25c59f25f851fdb5884f10562fbc
https://doi.org/10.1021/jo00092a019
https://doi.org/10.1021/jo00092a019
Publikováno v:
The Journal of Organic Chemistry. 58:5186-5191
Various cyanomethyleneamino pseudodipeptides were easily prepared in high yield by the Lewis acid catalyzed addition of trimethylsilyl cyanide to unstable aldimine intermediates, obtained from the reaction of N-protected α-amino aldehydes with C-pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::091a79ece1860a2f3e263a857ef7fb77
https://doi.org/10.1021/jo00071a031
https://doi.org/10.1021/jo00071a031
Publikováno v:
Tetrahedron Letters. 32:7579-7582
An easy and versatile general method for the preparation of the new peptide bond surrogate Ψ[CH(CN)NH], by the Lewis acid catalyzed reaction of N-protected α-amino aldehydes with a C-protected amino acid or peptide in the presence of TMSCN, is desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b136b8354dc7e299dc21f8de651ad3a9
https://doi.org/10.1016/0040-4039(91)80539-i
https://doi.org/10.1016/0040-4039(91)80539-i