Evaluation of biomimetic hyaluronic-based hydrogels with enhanced endogenous cell recruitment and cartilage matrix formation

Autor: Avner Yayon, Sibylle Grad, Nicole Kops, Andrea Lolli, M.L. Vainieri, Domenico D'Atri, G.J.V.M. van Osch, Kavitha Sivasubramaniyan, Mauro Alini, David Eglin

Publikováno v: Acta Biomaterialia, 101, 293-303. Elsevier
Acta Biomater

Biomaterials play a pivotal role in cell-free cartilage repair approaches, where cells must migrate through the scaffold, fill the defect, and then proliferate and differentiate facilitating tissue remodeling. Here we used multiple assays to test the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0394fc67e79f99f9334fcb0da1d02d57
https://pure.eur.nl/en/publications/0ede2bd1-7ed8-4154-92bb-64f7efe67e84

Drug delivery in intervertebral disc degeneration and osteoarthritis: Selecting the optimal platform for the delivery of disease-modifying agents

Autor: Fabio Colella, Jacopo Oieni, Bernardo P. Antunes, Marco Sorbona, Andrea Lolli, Serdar Capar, Luana Zerrillo, Domenico D'Atri, Yunpeng Cai, J. Garcia, Sonja Häckel, Florian P.Y. Barré, M.L. Vainieri, Laura B. Creemers

Publikováno v: Colella, F, Garcia, J P, Sorbona, M, Lolli, A, Antunes, B, D'Atri, D, Barré, F P Y, Oieni, J, Vainieri, M L, Zerrillo, L, Capar, S, Häckel, S, Cai, Y & Creemers, L B 2020, ' Drug delivery in intervertebral disc degeneration and osteoarthritis : Selecting the optimal platform for the delivery of disease-modifying agents ', Journal of Controlled Release, vol. 328, pp. 985-999 . https://doi.org/10.1016/j.jconrel.2020.08.041
Colella, Fabio; Garcia, João Pedro; Sorbona, Marco; Lolli, Andrea; Antunes, Bernardo; D'Atri, Domenico; Barré, Florian P Y; Oieni, Jacopo; Vainieri, Maria Letizia; Zerrillo, Luana; Capar, Serdar; Häckel, Sonja; Cai, Yunpeng; Creemers, Laura B (2020). Drug delivery in intervertebral disc degeneration and osteoarthritis: Selecting the optimal platform for the delivery of disease-modifying agents. Journal of controlled release, 328, pp. 985-999. Elsevier 10.1016/j.jconrel.2020.08.041
Journal of Controlled Release, 328, 985-999. ELSEVIER
Journal of Controlled Release, 328, 985-999. Elsevier
J Control Release

Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) as major cause of chronic low back pain represent the most common degenerative joint pathologies and are leading causes of pain and disability in adults. Articular cartilage (AC) and int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b2b3042e1889bd74d8bfb96e174150

Mechanical Stress Inhibits Early Stages of Endogenous Cell Migration: A Pilot Study in an Ex Vivo Osteochondral Model

Autor: Sibylle Grad, Mauro Alini, Gerjo J.V.M. van Osch, M.L. Vainieri, Avner Yayon

Publikováno v: Polymers, Vol 12, Iss 1754, p 1754 (2020)
Polymers
Volume 12
Issue 8
Polymers, 12 (8)
Polymers, 12(8)
Polymers, 12(8):1754. Multidisciplinary Digital Publishing Institute (MDPI)

Cell migration has a central role in osteochondral defect repair initiation and biomaterial-mediated regeneration. New advancements to reestablish tissue function include biomaterials and factors promoting cell recruitment, differentiation and tissue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5e374d73c6ff66388104f3c82ed189
https://doi.org/10.3390/polym12081754

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