Zobrazeno 1 - 10
of 62
pro vyhledávání: '"M.L. Mena"'
Publikováno v:
MethodsX, Vol 1, Iss C, Pp 175-180 (2014)
The analysis of the complexes between metal-based chemotherapeutic drugs and proteins in biological samples, such as cisplatin or oxaliplatin, can be a challenge due to metal strong reactivity towards S-donor molecules such as dithiothreitol (DTT) or
Externí odkaz:
https://doaj.org/article/b3f7fa3e92be47f69f4a604153359c9d
Autor:
M.L. Mena, A. Iglesias-Jiménez, M. Milagros Gómez-Gómez, G. Artiaga, Estefanía Moreno-Gordaliza
Publikováno v:
European Journal of Pharmaceutical Sciences. 132:96-105
Pt-S and Pt-N interactions resulting from the coordination of cisplatin, oxaliplatin and carboplatin to two synthetic peptides that differ from each other in one amino acid (Met or His) have been thoroughly studied in this work. The degree of Pt-bind
Autor:
Norbert Jakubowski, Alberto Tejedor, Boris Neumann, Alberto Lázaro, M.L. Mena, M. Milagros Gómez-Gómez, Irene Moraleja, Diego Esteban-Fernández
Publikováno v:
Talanta. 178:166-171
Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) has been revealed as a convenient technique for trace elemental imaging in tissue sections, providing elemental 2D distribution at a quantitative level. For quantification purpos
Akademický článek
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Akademický článek
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Publikováno v:
Talanta. 116:581-592
In this work, the reactivity of the citostatic drugs such as oxaliplatin, cisplatin and carboplatin towards proteins and the stability of Pt-protein complexes along their storage were evaluated. Neither native-PAGE nor nrSDS-PAGE seems to be suitable
Publikováno v:
Journal of Electroanalytical Chemistry. 615:69-74
A simple and effective amperometric biosensor based on PVC/TTF–TCNQ composite electrode is proposed for glucose determination. Glucose oxidase (GOx) was immobilized by crosslinking with glutaraldehyde. The TTF–TCNQ salt acts as a conducting phase
Publikováno v:
Journal of Electroanalytical Chemistry. 603:1-7
The construction and performance of a novel colloidal gold–carbon nanotubes (CNT) composite electrode using Teflon as the non-conducting binding material, is reported. The resulting Aucoll–CNT–Teflon electrode shows significantly improved respo
Publikováno v:
Biosensors and Bioelectronics. 22:730-736
The design of a new tyrosinase biosensor with improved stability and sensitivity is reported. The biosensor design is based on the construction of a graphite-Teflon composite electrode matrix in which the enzyme and colloidal gold nanoparticles are i
Publikováno v:
Electroanalysis. 17:2147-2155
A laccase biosensor, in which the enzyme was immobilized on N-succinimidyl-3-thiopropionate (NSTP)-modified gold electrodes, is reported. Two different approaches for the preparation of N-succinimidyl-terminated monolayers were evaluated: a) activati