Zobrazeno 1 - 10
of 31
pro vyhledávání: '"M.L. Kuravsky"'
Autor:
Aleksandra K. Melnikova, Vladimir I. Muronetz, K V Kulikova, M.L. Kuravsky, Irina A. Sevostyanova
Publikováno v:
Biomeditsinskaya Khimiya. 66:372-377
The somatic isoform of the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH; EC1.2.1.12) is involved in such crucial for cancer cells development pathways as induction of apoptosis and glycolytic regulation. At the same time, sperm-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5cfc8319937b844aff6cda6974c31f
https://doi.org/10.18097/pbmc20206605372
https://doi.org/10.18097/pbmc20206605372
Autor:
M.L. Kuravsky, K.V. Barinova, Alexander M. Arutyunyan, Elena V. Schmalhausen, Vladimir I. Muronetz, Marina V. Serebryakova
Publikováno v:
International Journal of Biological Macromolecules. 96:35-43
Expression of human alpha-synuclein in E. coli cells is known to result in a mixture of the wild type alpha-synuclein and the protein containing Tyr136Cys substitution due to the translational error. The amount of Cys136 alpha-synuclein (Cys136-AS) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::befc1c4db321165a77275c184c018099
https://doi.org/10.1016/j.ijbiomac.2016.12.011
https://doi.org/10.1016/j.ijbiomac.2016.12.011
Autor:
M.L. Kuravsky, K.V. Barinova, Evgeniya Khomyakova, Vladimir I. Muronetz, Elena V. Schmalhausen
Publikováno v:
Biochemical and Biophysical Research Communications. 482:1265-1270
Influence of the immunization procedure on the specificity of the produced antibodies towards different conformations of the antigen was investigated. It was demonstrated that intravenous immunization of a rabbit with an adjuvant-free solution of rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c47c0d4ad31d232fcd996c4c313a20
https://doi.org/10.1016/j.bbrc.2016.12.026
https://doi.org/10.1016/j.bbrc.2016.12.026
Publikováno v:
Biochemistry (Moscow). 80:1672-1689
This review is focused on the mammalian sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDS). GAPDS plays the major role in the production of energy required for sperm cell movement and does not perform non-glycolytic functions that are ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6223bd676321afd9f6f244e67e917ae
https://doi.org/10.1134/s0006297915130040
https://doi.org/10.1134/s0006297915130040
Autor:
Vladimir I. Muronetz, Yuriy F. Zuev, Pavel I. Semenyuk, Elena A. Ermakova, M.L. Kuravsky, Olga Makshakova
Publikováno v:
Journal of Structural Biology. 190:224-235
Tissue specific isoforms of human glyceraldehyde-3-phosphate dehydrogenase, somatic (GAPD) and sperm-specific (GAPDS), have been reported to display different levels of both stability and catalytic activity. Here we apply MD simulations to investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50bcb201fe4da55252d1e28b32875d9b
https://doi.org/10.1016/j.jsb.2015.04.004
https://doi.org/10.1016/j.jsb.2015.04.004
Autor:
Yu. L. Elkina, L. F. Kurilo, S. S. Khayat, E. E. Bragina, Elena V. Schmalhausen, M. Y. Sukhomlinova, M.L. Kuravsky
Publikováno v:
Andrologia. 49(2)
Summary The fibrous sheath is a unique cytoskeletal structure surrounding the axoneme and outer dense fibres of the sperm flagellum. Dysplasia of the fibrous sheath (DFS) is a defect of spermatozoa observed in severe asthenozoospermic patients and ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04152f088334e6b1cef7d23714b67552
https://pubmed.ncbi.nlm.nih.gov/27135296
https://pubmed.ncbi.nlm.nih.gov/27135296
Autor:
Vladimir I. Muronetz, Kseniya V. Kulikova, Elena V. Schmalhausen, Irina A. Sevostyanova, M.L. Kuravsky
Publikováno v:
Biochemical and Biophysical Research Communications. 427:649-653
Sperm-specific glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDS) is normally expressed only in sperms, but not in somatic tissues. Analysis of the expression of GAPDS mRNA in different cancer cell lines shows that the content of GAPD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f92ae7e878ddefa6274ec66b8bf534
https://doi.org/10.1016/j.bbrc.2012.09.115
https://doi.org/10.1016/j.bbrc.2012.09.115
Autor:
M.L. Kuravsky, Yu. L. Elkina, S. V. Stogov, M. A. Eldarov, Vladimir I. Muronetz, Elena V. Schmalhausen
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1804:2207-2212
Sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDS) is bound to the fibrous sheath of the sperm flagellum through the hydrophobic N-terminal domain of the enzyme molecule. Expression of human GAPDS in E.coli cells yields inactive and inso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7864109d419bcd06d5118d148bb1ac3b
https://doi.org/10.1016/j.bbapap.2010.09.002
https://doi.org/10.1016/j.bbapap.2010.09.002
Publikováno v:
Biochemistry (Moscow). 73:185-191
Glyceraldehyde-3-phosphate dehydrogenase (GAPDs) was purified from human sperms and properties of the enzyme were investigated. After sonication of sperms, the most part of GAPDs is associated with the insoluble cell fraction. Trypsin treatment resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d39cbae0ee93c2ff5909aad5ba9d80e9
https://doi.org/10.1134/s0006297908020107
https://doi.org/10.1134/s0006297908020107
Autor:
Vladimir I. Muronetz, M.L. Kuravsky
Publikováno v:
Biochemistry (Moscow). 72:744-749
The elucidation of the interdependence between structural features and functions of somatic and sperm-specific isoenzymes of glyceraldehyde-3-phosphate dehydrogenase (GAPD and GAPDS, respectively) was the goal of comparative analysis of their primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c61d79305920402ff9ec5dbe87857c7
https://doi.org/10.1134/s0006297907070085
https://doi.org/10.1134/s0006297907070085